Human IL6 / Interleukin-6 Protein | Sino Biological 10395-HNAE product information

product summary

company name :

Sino Biological

product type :

protein

product name :

Human IL6 / Interleukin-6 Protein

catalog :

10395-HNAE

quantity :

1 mg

price :

2268 USD

more info or order :

Sino Biological product webpage

citations: 15

Reference
Chen Z, Zhang W, Wang D, Luo R, Yao Y, Tao X, et al. CD44 is a macrophage receptor for TcdB from Clostridioides difficile that via its lysine-158 succinylation contributes to inflammation. Gut Microbes. 2025;17:2506192 pubmed publisher
Moritz C, Tholance Y, Borowczyk C, Jospin F, Paul S, Antoine J, et al. Cytokine Signature Unveils Subgroups of Patients With Immune-Mediated Sensory Neuronopathies. J Peripher Nerv Syst. 2025;30:e70008 pubmed publisher
Lian P, Li L, Lu R, Zhang B, Wazir J, Gu C, et al. S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis. Cell Death Dis. 2025;16:31 pubmed publisher
Hung C, Wu S, Yao C, Yeh H, Lin C, Chu C, et al. Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer. Nat Commun. 2024;15:7885 pubmed publisher
Yuan L, Wang Y, Xie R, Lin D, Wang X. Generation and characterization of iPS cell line (SYSUSHi002-A) from PBMCs of an AML patient with TP53 mutation. Stem Cell Res. 2023;73:103230 pubmed publisher
Zhang Z, Ju C, Wu L, Yan H, Hong W, Chen H, et al. Therapeutic potency of compound RMY-205 for pulmonary fibrosis induced by SARS-CoV-2 nucleocapsid protein. Cell Chem Biol. 2023;30:261-277.e8 pubmed publisher
Dobson D, Holle L, Lin F, Huffman J, Luyendyk J, Flick M, et al. Novel genetic regulators of fibrinogen synthesis identified by an in vitro experimental platform. J Thromb Haemost. 2023;21:522-533 pubmed publisher
Zheng Z, Chu M, Lin W, Zheng Y, Xu X, Chen Y, et al. Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma. Cell Death Dis. 2022;13:496 pubmed publisher
Cao W, Zhang Y, Li A, Yu P, Song L, Liang J, et al. Curcumin reverses hepatic epithelial mesenchymal transition induced by trichloroethylene by inhibiting IL-6R/STAT3. Toxicol Mech Methods. 2021;31:589-599 pubmed publisher
Deng R, Zhang H, Huang J, Cai R, Wang Y, Chen Y, et al. MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis. Autophagy. 2020;:1-19 pubmed publisher
Hou P, Luo L, Chen H, Chen Q, Bian X, Wu S, et al. Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment. Mol Cell. 2020;78:1192-1206.e10 pubmed publisher
Te Winkel J, Drucker N, Morocho B, Shelley W, Markel T. Interleukin-6 Therapy Improves Intestinal Recovery Following Ischemia. J Surg Res. 2019;239:142-148 pubmed publisher
Lu X, Wo G, Li B, Xu C, Wu J, Jiang C, et al. The anti-inflammatory NHE-06 restores antitumor immunity by targeting NF-κB/IL-6/STAT3 signaling in hepatocellular carcinoma. Biomed Pharmacother. 2018;102:420-427 pubmed publisher
Liu L, Leung K, Chan D, Wang Y, Ma D, Leung C. Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening. Cell Death Dis. 2014;5:e1293 pubmed publisher
Takeichi C, Okazaki H. [Genetic method of study of fungi. 1. Isolation of mutants]. Tanpakushitsu Kakusan Koso. 1966;11:1271-3 pubmed

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product information

Catalog Number :

10395-HNAE

Product Name :

Human IL6 / Interleukin-6 Protein

Product Type :

Protein

Host Species :

E. coli

Conjugation :

Native

Size :

1 mg

List Price :

2268 USD

Gene ID :

NP_000591.1

Product Description :

A DNA sequence encoding the mature form of human IL6 (NP_000591.1) (Val30-Met212) was expressed with an initial Met at the N-terminus.

SpeciesSummary :

Human

ALTnames :

BSF2,BSF-2,CDF,HGF,HSF,IFNB2,IFN-beta-2,IL-6

Purity :

≥ 95 % as determined by SDS-PAGE

Buffer :

Lyophilized from sterile PBS, pH 7.4.

Packaging :

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Storage :

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

more info or order :

Sino Biological product webpage