Human PD1 / PDCD1 Protein (His Tag) | Sino Biological 10377-H08H product information

product summary

company name :

Sino Biological

product type :

protein

product name :

Human PD1 / PDCD1 Protein (His Tag)

catalog :

10377-H08H

quantity :

1 mg

price :

2268 USD

more info or order :

Sino Biological product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
FACS; human ELISA; human	Khedri M, Abnous K, Rafatpanah H, Nabavinia M, Taghdisi S, Ramezani M. Development and Evaluation of Novel Aptamers Specific for Human PD1 Using Hybrid Systematic Evolution of Ligands by Exponential Enrichment Approach. Immunol Invest. 2020;49:535-554 pubmed publisher
ELISA; human	Fan Z, Tian Y, Chen Z, Liu L, Zhou Q, He J, et al. Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors. EMBO Mol Med. 2020;12:e11571 pubmed publisher
ELISA; human	Pluim D, Ros W, van Bussel M, Brandsma D, Beijnen J, Schellens J. Enzyme linked immunosorbent assay for the quantification of nivolumab and pembrolizumab in human serum and cerebrospinal fluid. J Pharm Biomed Anal. 2019;164:128-134 pubmed publisher
	Feng Y, Deyanat Yazdi G, Newburn K, Potter S, Wortinger M, Ramirez M, et al. PD-1 antibody interactions with Fc gamma receptors enable PD-1 agonism to inhibit T cell activation - therapeutic implications for autoimmunity. J Autoimmun. 2024;149:103339 pubmed publisher
	Gu T, Tian X, Wang Y, Yang W, Li W, Song M, et al. Repurposing pentamidine for cancer immunotherapy by targeting the PD1/PD-L1 immune checkpoint. Front Immunol. 2023;14:1145028 pubmed publisher
	Williams D, Cassel J, Zhu J, Yang J, de Voogd N, Matainaho T, et al. Thorectidiol A Isolated from the Marine Sponge Dactylospongia elegans Disrupts Interactions of the SARS-CoV-2 Spike Receptor Binding Domain with the Host ACE2 Receptor. J Nat Prod. 2023;86:582-588 pubmed publisher
	Wang Y, Gu T, Tian X, Li W, Zhao R, Yang W, et al. A Small Molecule Antagonist of PD-1/PD-L1 Interactions Acts as an Immune Checkpoint Inhibitor for NSCLC and Melanoma Immunotherapy. Front Immunol. 2021;12:654463 pubmed publisher
	Zhu Y, Hu X, Feng L, Yang Z, Zhou L, Duan X, et al. Enhanced Therapeutic Efficacy of a Novel Oncolytic Herpes Simplex Virus Type 2 Encoding an Antibody Against Programmed Cell Death 1. Mol Ther Oncolytics. 2019;15:201-213 pubmed publisher
	Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
	Mitchell L, Yagiz K, Hofacre A, Viaud S, Munday A, Espinoza F, et al. PD-L1 checkpoint blockade delivered by retroviral replicating vector confers anti-tumor efficacy in murine tumor models. Oncotarget. 2019;10:2252-2269 pubmed publisher
	Zhao M, Wang J, Luo M, Luo H, Zhao M, Han L, et al. Rapid development of stable transgene CHO cell lines by CRISPR/Cas9-mediated site-specific integration into C12orf35. Appl Microbiol Biotechnol. 2018;102:6105-6117 pubmed publisher
	Shahdordizadeh M, Taghdisi S, Sankian M, Ramezani M, Abnous K. Design, isolation and evaluation of the binding efficiency of a DNA aptamer against interleukin 2 receptor alpha, in vitro. Int Immunopharmacol. 2017;53:96-104 pubmed publisher
	Li D, Xu J, Wang Z, Gong Z, Liu J, Zheng Y, et al. Epitope mapping reveals the binding mechanism of a functional antibody cross-reactive to both human and murine programmed death 1. MAbs. 2017;9:628-637 pubmed publisher
	Wang F, Ma J, Liu J, Jin H, Huang D. Synthetic small peptides acting on B7H1 enhance apoptosis in pancreatic cancer cells. Mol Med Rep. 2012;6:553-7 pubmed publisher

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product information

Catalog Number :

10377-H08H

Product Name :

Human PD1 / PDCD1 Protein (His Tag)

Product Type :

Protein

Host Species :

HEK293 Cells

Conjugation :

C-His

Size :

1 mg

List Price :

2268 USD

Gene ID :

NP_005009.2

Product Description :

A DNA sequence encoding the extracellular domain (Met 1-Gln 167) of human PD1 (NP_005009.2) was expressed with a C-terminal polyhistidine tag.

SpeciesSummary :

Human

ALTnames :

CD279,hPD-1,hPD-l,hSLE1,PD1,PD-1,SLEB2

Purity :

> 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC.

Buffer :

Lyophilized from sterile 50mM MOPS, 500mM NaCl, pH 7.0

Packaging :

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Storage :

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

more info or order :

Sino Biological product webpage