product summary
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company name :
Sino Biological
product type :
protein
product name :
Human PD1 / PDCD1 / CD279 Protein (Fc Tag)
catalog :
10377-H02H
quantity :
50 µg
price :
178 USD
more info or order :
Sino Biological product webpage
citations: 6
Reference
Zhang H, Zhang Y, Geng Y, Zhen X, Wang X, Yin Q, et al. The Exploration of Indole-Based LSD1-Targeted Inhibitors for Enhanced Immune Response in Gastric Cancer via the PD-L1/PD-1 Axis. J Med Chem. 2025;68:9260-9278 pubmed publisher
Zheng R, Gao F, Mao Z, Xiao Y, Yuan L, Huang Z, et al. LncRNA BCCE4 Genetically Enhances the PD-L1/PD-1 Interaction in Smoking-Related Bladder Cancer by Modulating miR-328-3p-USP18 Signaling. Adv Sci (Weinh). 2023;10:e2303473 pubmed publisher
Liu H, Xiong X, Wu J, Chen H, Zhou Y, Ji S, et al. Discovery of acridine-based LSD1 inhibitors as immune activators targeting LSD1 in gastric cancer. Eur J Med Chem. 2023;251:115255 pubmed publisher
Yi M, Wu Y, Niu M, Zhu S, Zhang J, Yan Y, et al. Anti-TGF-β/PD-L1 bispecific antibody promotes T cell infiltration and exhibits enhanced antitumor activity in triple-negative breast cancer. J Immunother Cancer. 2022;10: pubmed publisher
Yin H, Zhou X, Huang Y, King G, Collins B, Gao Y, et al. Rational Design of Potent Peptide Inhibitors of the PD-1:PD-L1 Interaction for Cancer Immunotherapy. J Am Chem Soc. 2021;143:18536-18547 pubmed publisher
Wu X, Li F, Li Y, Yu Y, Liang C, Zhang B, et al. A PD-L1 Aptamer Selected by Loss-Gain Cell-SELEX Conjugated with Paclitaxel for Treating Triple-Negative Breast Cancer. Med Sci Monit. 2020;26:e925583 pubmed publisher
image
image 1 :
Sino Biological 10377-H02H image 1
product information
Catalog Number :
10377-H02H
Product Name :
Human PD1 / PDCD1 / CD279 Protein (Fc Tag)
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-human IgG1-Fc
Size :
50 µg
List Price :
178 USD
Gene ID :
NP_005009.2
Product Description :
A DNA sequence encoding the human PDCD1 (NP_005009.2) (Met1-Gln167) was expressed with the Fc region of human IgG1 at the C-terminus.
SpeciesSummary :
Human
ALTnames :
CD279,hPD-1,hPD-l,hSLE1,PD1,PD-1,SLEB2
Purity :
> 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC.
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.