product summary
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company name :
Sino Biological
product type :
protein
product name :
Human CD32a / FCGR2A Protein (167 Arg, His Tag)
catalog :
10374-H08H
quantity :
1 mg
price :
1926 USD
more info or order :
Sino Biological product webpage
citations: 5
Reference
Knorr D, Blanchard L, Leidner R, Jensen S, Meng R, Jones A, et al. FcγRIIB is an immune checkpoint limiting the activity of Treg-targeting antibodies in the tumor microenvironment. Cancer Immunol Res. 2023;: pubmed publisher
Park J, Choi H, Jung K, Lee K, Shim J, Park K, et al. Production of recombinant human IgG1 Fc with beneficial N-glycosylation pattern for anti-inflammatory activity using genome-edited chickens. Commun Biol. 2023;6:589 pubmed publisher
HUBBARD J, Pyzik M, Rath T, Kozicky L, Sand K, Gandhi A, et al. FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity. J Exp Med. 2020;217: pubmed publisher
Hayes J, Frostell A, Cosgrave E, Struwe W, Potter O, Davey G, et al. Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions. J Proteome Res. 2014;13:5471-85 pubmed publisher
Schmitz H, Gabriel M, Emmerich P. Specific detection of antibodies to different flaviviruses using a new immune complex ELISA. Med Microbiol Immunol. 2011;200:233-9 pubmed publisher
image
image 1 :
Sino Biological 10374-H08H image 1
product information
Catalog Number :
10374-H08H
Product Name :
Human CD32a / FCGR2A Protein (167 Arg, His Tag)
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-His
Size :
1 mg
List Price :
1926 USD
Gene ID :
P12318-1
Product Description :
A DNA sequence encoding the extracellular domain (Met1-Ile218) of human FCGR2A (P12318-1, with Natural variant R167) was expressed with a C-terminal polyhistidine tag.
SpeciesSummary :
Human
ALTnames :
FCGR2,CD32,CD32A,CDw32,FCG2,FcgammaRIIa,FcGR,FCGR2A1,IGFR2,Fc-gamma-RIIa
Purity :
≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC. ≥ 90 % as determined by SEC-MALS(Routinely tested).
Buffer :
Lyophilized from sterile PBS, pH 7.5
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.