Human PTP1B / PTPN1 Protein (His Tag) | Sino Biological 10304-H07E product information

product summary

company name :

Sino Biological

product type :

protein

product name :

Human PTP1B / PTPN1 Protein (His Tag)

catalog :

10304-H07E

quantity :

100 µg

price :

358 USD

more info or order :

Sino Biological product webpage

citations: 15

Reference
Wang Y, Li X, Wu S, Gongpan P, Yang Y, Huang M, et al. Antidiabetic diarylheptanoids from the leaves of Amomum tsao-ko and their inhibition mechanism against α-glucosidase. Fitoterapia. 2025;183:106566 pubmed publisher
Dong G, Gong L, Zhang Q, Yao W, Shi Y, Gu Z, et al. Glycosylation Modification Balances the Aqueous Solubility of Lipidated Peptides and Facilitates Their Biostability. Bioconjug Chem. 2025;36:1004-1012 pubmed publisher
Li X, Wang T, Wu S, Huang X, Ma Y, Geng C. New C-linked diarylheptanoid dimers as potential α-glucosidase inhibitors evidenced by biological, spectral and theoretical approaches. Int J Biol Macromol. 2025;295:139496 pubmed publisher
Cui C, Wu S, Chen J, Gongpan P, Guan M, Geng C. Sesquiterpenoids from Alpinia oxyphylla with GLP-1 Stimulative Effects through Ca2+/CaMKII and PKA Pathways and Multiple-Enzyme Inhibition. J Agric Food Chem. 2023;71:16148-16159 pubmed publisher
Wang T, Wu S, Liu P, Chen J, Zhang X, Geng C. Diarylheptanoids with hypoglycemic potency from the rhizomes of Kaempferia galanga. Fitoterapia. 2023;167:105502 pubmed publisher
Zhang C, Yang X, Meng X, Wu L, Liu X, Gao J, et al. Discovery of Novel PTP1B Inhibitors with Once-Weekly Therapeutic Potential for Type 2 Diabetes: Design, Synthesis, and In Vitro and In Vivo Investigations of BimBH3 Peptide Analogues. J Med Chem. 2023;66:3030-3044 pubmed publisher
Zhang Z, Shang Z, Jiang Y, Qu Z, Yang R, Zhang J, et al. Selective Inhibition of PTP1B by New Anthraquinone Glycosides from Knoxia valerianoides. J Nat Prod. 2022;85:2836-2844 pubmed publisher
Zhang H, Liu J, Yang Z, Zeng L, Wei K, Zhu L, et al. TCR activation directly stimulates PYGB-dependent glycogenolysis to fuel the early recall response in CD8+ memory T cells. Mol Cell. 2022;82:3077-3088.e6 pubmed publisher
He X, Chen J, Li T, Zhang X, Guo Y, Zhang X, et al. Nineteen New Flavanol-Fatty Alcohol Hybrids with α-Glucosidase and PTP1B Dual Inhibition: One Unusual Type of Antidiabetic Constituent from Amomum tsao-ko. J Agric Food Chem. 2020;68:11434-11448 pubmed publisher
Zhang C, Geng C, Huang X, Zhang X, Chen J. Antidiabetic Stilbenes from Peony Seeds with PTP1B, α-Glucosidase, and DPPIV Inhibitory Activities. J Agric Food Chem. 2019;67:6765-6772 pubmed publisher
Chen X, Gan Q, Feng C, Liu X, Zhang Q. Virtual Screening of Novel and Selective Inhibitors of Protein Tyrosine Phosphatase 1B over T-Cell Protein Tyrosine Phosphatase Using a Bidentate Inhibition Strategy. J Chem Inf Model. 2018;58:837-847 pubmed publisher
Wang Q, Zhang S, Zhong Y, Yang X, Li Z, Li H. Preparation of Yellow-Green-Emissive Carbon Dots and Their Application in Constructing a Fluorescent Turn-On Nanoprobe for Imaging of Selenol in Living Cells. Anal Chem. 2017;89:1734-1741 pubmed publisher
Papp D, KovÃ¡cs T, Billes V, Varga M, TarnÃ³ci A, Hackler L, et al. AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects. Autophagy. 2016;12:273-86 pubmed publisher
Ong J, Yap C, Ang W. Rational design of selective organoruthenium inhibitors of protein tyrosine phosphatase 1B. Inorg Chem. 2012;51:12483-92 pubmed publisher
Fuchs V. The contribution of health services to the American economy. Milbank Mem Fund Q. 1966;44:65-103 pubmed

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product information

Catalog Number :

10304-H07E

Product Name :

Human PTP1B / PTPN1 Protein (His Tag)

Product Type :

Protein

Host Species :

E. coli

Conjugation :

N-His

Size :

100 µg

List Price :

358 USD

Gene ID :

NP_002818.1

Product Description :

A DNA sequence encoding the human PTPN1 (NP_002818.1) (Glu 2-Asn 321) was expressed, with a polyhistide tag at the N-terminus.

SpeciesSummary :

Human

ALTnames :

PTP1B

Purity :

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Buffer :

Supplied as sterile 10mM Hepes, 150mM NaCl, 1mM DTT, pH 7.5.

Packaging :

Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.

Storage :

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

more info or order :

Sino Biological product webpage