This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Sino Biological
product type :
protein
product name :
Human CD32b / FCGR2B Protein (ECD, His & AVI Tag)
catalog :
10259-H27H
quantity :
100 µg
price :
298 USD
citations: 2
Reference
de Taeye S, Bentlage A, Mebius M, Meesters J, Lissenberg Thunnissen S, Falck D, et al. FcγR Binding and ADCC Activity of Human IgG Allotypes. Front Immunol. 2020;11:740 pubmed publisher
Bruggeman C, Dekkers G, Bentlage A, Treffers L, Nagelkerke S, Lissenberg Thunnissen S, et al. Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fc? Receptor Profile. J Immunol. 2017;199:204-211 pubmed publisher
product information
Note :
Online
Catalog Number :
10259-H27H
Product Name :
Human CD32b / FCGR2B Protein (ECD, His & AVI Tag)
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-AVI & His
Size :
100 µg
List Price :
298 USD
Gene ID :
NP_001002274.1
Product Description :
A DNA sequence encoding the extracellular domain (Ala 46-Ile 224) of mature human CD32b (NP_001002274.1) protein was fused with a signal peptide at the N-terminus and a c-terminal polyhistidine tagged AVI tag at the C-terminus.
SpeciesSummary :
Human
ALTnames :
FCGR2B
Specificity :
1. Immobilized human CD32b-AVI-His (Cat:10259-H27H) at 10 μg/ml (100 μl/well) can bind biotinylated Human IgG1, The EC50 of biotinylated Human IgG1 is 0.20-0.48 μg/ml. 2. Using the Octet RED System, the affinity constant (Kd) of CD32B / Fcgr2b Protein, Human, Recombinant (His & AVI Tag)(Cat: 10259-H27H) bound to Herceptin was 1.5 nM.
Purity :
> 95 % as determined by SDS-PAGE
Buffer :
Lyophilized from sterile PBS, pH 7.4
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.