product summary
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company name :
Sino Biological
product type :
protein
product name :
Human HER3 / ErbB3 Protein (ECD, Fc Tag)
catalog :
10201-H02H
quantity :
1 mg
price :
1938 USD
more info or order :
Sino Biological product webpage
citations: 5
Reference
Zong H, Li X, Han L, Wang L, Liu J, Yue Y, et al. A novel bispecific antibody drug conjugate targeting HER2 and HER3 with potent therapeutic efficacy against breast cancer. Acta Pharmacol Sin. 2024;: pubmed publisher
Ding X, Gu W, Zhong Y, Hao X, Liu J, Xia S, et al. A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity. EBioMedicine. 2020;60:102996 pubmed publisher
Dahlsson Leitao C, Rinne S, Mitran B, Vorobyeva A, Andersson K, Tolmachev V, et al. Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of 68Ga-Labeled Tracers. Int J Mol Sci. 2019;20: pubmed publisher
Malm M, Kronqvist N, Lindberg H, Gudmundsdotter L, Bass T, Frejd F, et al. Inhibiting HER3-mediated tumor cell growth with affibody molecules engineered to low picomolar affinity by position-directed error-prone PCR-like diversification. PLoS ONE. 2013;8:e62791 pubmed publisher
Vicente Alique E, Núñez Ramírez R, Vega J, Hu P, Martinez Salazar J. Size and conformational features of ErbB2 and ErbB3 receptors: a TEM and DLS comparative study. Eur Biophys J. 2011;40:835-42 pubmed publisher
image
image 1 :
Sino Biological 10201-H02H image 1
product information
Catalog Number :
10201-H02H
Product Name :
Human HER3 / ErbB3 Protein (ECD, Fc Tag)
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-human IgG1-Fc
Size :
1 mg
List Price :
1938 USD
Gene ID :
NP_001973.2
Product Description :
A DNA sequence encoding the extracellular domain (Met 1-Thr 643) of human ErbB3 (NP_001973.2) precursor was expressed with the C-terminal fused Fc region of human IgG1.
SpeciesSummary :
Human
ALTnames :
c-erbB3,c-erbB-3,ErbB-3,erbB3-S,FERLK,HER3,LCCS2,MDA-BF-1,p180-ErbB3,p45-sErbB3,p85-sErbB3,VSCN1
Purity :
≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.