product summary
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company name :
Sino Biological
product type :
protein
product name :
Human IL-1 beta / IL1B (E6K) Protein (pro form, His Tag)
catalog :
10139-H07E
quantity :
1 mg
price :
2918 USD
more info or order :
Sino Biological product webpage
citations: 8
Reference
Chen Z, Zhang W, Wang D, Luo R, Yao Y, Tao X, et al. CD44 is a macrophage receptor for TcdB from Clostridioides difficile that via its lysine-158 succinylation contributes to inflammation. Gut Microbes. 2025;17:2506192 pubmed publisher
Kim S, Seo S. Caspase-3 targets pro-interleukin-1β (IL-1β) to restrict inflammation. FEBS Lett. 2024;598:1366-1374 pubmed publisher
Esnault S, Kelly E, Johnson S, Delain L, Haedt M, Noll A, et al. Matrix Metalloproteinase-9-Dependent Release of IL-1β by Human Eosinophils. Mediators Inflamm. 2019;2019:7479107 pubmed publisher
Tang S, Deng S, Guo J, Chen X, Zhang W, Cui Y, et al. Deep Coverage Tissue and Cellular Proteomics Revealed IL-1? Can Independently Induce the Secretion of TNF-Associated Proteins from Human Synoviocytes. J Immunol. 2018;200:821-833 pubmed publisher
Ainscough J, MacLeod T, McGonagle D, Brakefield R, Baron J, Alase A, et al. Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36?. Proc Natl Acad Sci U S A. 2017;114:E2748-E2757 pubmed publisher
Edye M, Brough D, Allan S. Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 Cleavage. J Biol Chem. 2015;290:25374-81 pubmed publisher
Lamont E, O Grady S, Davis W, Eckstein T, Sreevatsan S. Infection with Mycobacterium avium subsp. paratuberculosis results in rapid interleukin-1? release and macrophage transepithelial migration. Infect Immun. 2012;80:3225-35 pubmed publisher
Azad N, Iyer A, Wang L, Liu Y, Lu Y, Rojanasakul Y. Reactive oxygen species-mediated p38 MAPK regulates carbon nanotube-induced fibrogenic and angiogenic responses. Nanotoxicology. 2013;7:157-68 pubmed publisher
image
image 1 :
Sino Biological 10139-H07E image 1
product information
Catalog Number :
10139-H07E
Product Name :
Human IL-1 beta / IL1B (E6K) Protein (pro form, His Tag)
Product Type :
Protein
Host Species :
E. coli
Conjugation :
N-His
Size :
1 mg
List Price :
2918 USD
Gene ID :
NP_000567.1
Product Description :
A DNA sequence encoding the pro form of human IL1β (NP_000567.1, with mutation Glu 6 Lys) (Met 1-Ser 269) was fused with a polyhistidine tag at the N-terminus.
SpeciesSummary :
Human
ALTnames :
IL-1,IL1beta,IL1-BETA,IL1F2,IL-1B
Purity :
≥ 90 % as determined by SDS-PAGE
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.