product summary
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company name :
Sino Biological
product type :
protein
product name :
Human CD155 / PVR / NECL5 Protein (Fc Tag)
catalog :
10109-H02H
quantity :
1 mg
price :
1926 USD
more info or order :
Sino Biological product webpage
citations: 5
Reference
Hansen K, Kumar S, Logronio K, Whelan S, Qurashi S, Cheng H, et al. COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade. Cancer Immunol Immunother. 2021;70:3525-3540 pubmed publisher
Zhang C, Wang Y, Xun X, Wang S, Xiang X, Hu S, et al. TIGIT Can Exert Immunosuppressive Effects on CD8+ T Cells by the CD155/TIGIT Signaling Pathway for Hepatocellular Carcinoma In Vitro. J Immunother. 2020;43:236-243 pubmed publisher
Wang F, Wang Y, Wang L, Wang T, Bai Y. TIGIT expression levels on CD4+ T cells are correlated with disease severity in patients with psoriasis. Clin Exp Dermatol. 2018;43:675-682 pubmed publisher
Chan C, Martinet L, Gilfillan S, Souza Fonseca Guimaraes F, Chow M, Town L, et al. The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions. Nat Immunol. 2014;15:431-8 pubmed publisher
Hou S, Ge K, Zheng X, Wei H, Sun R, Tian Z. CD226 protein is involved in immune synapse formation and triggers Natural Killer (NK) cell activation via its first extracellular domain. J Biol Chem. 2014;289:6969-77 pubmed publisher
image
image 1 :
Sino Biological 10109-H02H image 1
product information
Catalog Number :
10109-H02H
Product Name :
Human CD155 / PVR / NECL5 Protein (Fc Tag)
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-human IgG1-Fc
Size :
1 mg
List Price :
1926 USD
Gene ID :
P15151-1
Product Description :
A DNA sequence encoding the extracellular domain (Met1-Asn343) of human CD155 (P15151-1) was expressed with the C-terminal fused Fc region of human IgG1.
SpeciesSummary :
Human
ALTnames :
CD155,HVED,NECL5,Necl-5,PVS,TAGE4
Purity :
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Buffer :
Lyophilized from sterile 50mM Tris, 100mM NaCl, 100mM Arg, pH 7.5.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.