product summary
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company name :
Sino Biological
product type :
protein
product name :
Human GSK3B Protein (His Tag)
catalog :
10044-H07B
quantity :
50 µg
price :
258 USD
more info or order :
Sino Biological product webpage
citations: 6
Reference
He D, Zhang X, Su J, Zhang Q, Zhao L, Wu T, et al. Identification of AS1842856 as a novel small-molecule GSK3α/β inhibitor against Tauopathy by accelerating GSK3α/β exocytosis. Aging Cell. 2024;:e14336 pubmed publisher
Zhu S, Al Mathkour M, Cao L, Khalafi S, Chen Z, Poveda J, et al. CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis. Cell Rep. 2023;42:112005 pubmed publisher
Yue S, Wang L, Demartino G, Zhao F, Liu Y, Sieber M. Highly conserved shifts in ubiquitin-proteasome system (UPS) activity drive mitochondrial remodeling during quiescence. Nat Commun. 2022;13:4462 pubmed publisher
Li M, Fan L, Han D, Yu Z, Ma J, Liu Y, et al. Ribosomal S6 protein kinase 4 promotes radioresistance in esophageal squamous cell carcinoma. J Clin Invest. 2020;130:4301-4319 pubmed publisher
Gao J, Long L, Xu F, Feng L, Liu Y, Shi J, et al. Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischemia/reperfusion injury by inhibiting GSK-3β-mediated activation of autophagy. Br J Pharmacol. 2019;: pubmed publisher
Dunning C, McGauran G, Willén K, Gouras G, O Connell D, Linse S. Direct High Affinity Interaction between Aβ42 and GSK3α Stimulates Hyperphosphorylation of Tau. A New Molecular Link in Alzheimer's Disease?. ACS Chem Neurosci. 2016;7:161-70 pubmed publisher
image
image 1 :
Sino Biological 10044-H07B image 1
product information
Catalog Number :
10044-H07B
Product Name :
Human GSK3B Protein (His Tag)
Product Type :
Protein
Host Species :
Baculovirus-Insect Cells
Conjugation :
N-His
Size :
50 µg
List Price :
258 USD
Gene ID :
NP_002084.2
Product Description :
The amino acids corresponding to the full length of human GSK3B isoform 1 (NP_002084.2) (Met 1-Thr 433) was fused with a polyhistidine tag at the N-terminus.
SpeciesSummary :
Human
ALTnames :
GSK-3 beta/GSK3B
Purity :
≥ 90 % as determined by SDS-PAGE.
Buffer :
Supplied as sterile 20 mM PB, 500 mM NaCl, 10% Glycerol, 0.4 mM PMSF, 1 mM GSSG, 5 mM GSH, pH 7.0.
Packaging :
Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.