product summary
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company name :
Sino Biological
product type :
protein
product name :
Human HER2 / ErbB2 Protein
catalog :
10004-HCCH
quantity :
1 mg
price :
2316 USD
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • ELISA; human
Agnolon V, Contato A, Meneghello A, Tagliabue E, Toffoli G, Gion M, et al. ELISA assay employing epitope-specific monoclonal antibodies to quantify circulating HER2 with potential application in monitoring cancer patients undergoing therapy with trastuzumab. Sci Rep. 2020;10:3016 pubmed publisher
Kohnehrouz B, Ehsasatvatan M. Redesigning amino/carboxyl ends of DARPin G3 for high thermostability and production in tobacco transplastomic plants. Plant Cell Rep. 2024;43:210 pubmed publisher
Franco Mateos E, Souza Egipsy V, Garc xed a Est xe9 vez L, P xe9 rez Garc xed a J, Gion M, Garrig xf3 s L, et al. Exploring the Combined Action of Adding Pertuzumab to Branded Trastuzumab versus Trastuzumab Biosimilars for Treating HER2+ Breast Cancer. Int J Mol Sci. 2024;25: pubmed publisher
Go E, Lee J, Cho J, Kwon N, Choi J, Kwon I. Enhanced therapeutic potential of antibody fragment via IEDDA-mediated site-specific albumin conjugation. J Biol Eng. 2024;18:23 pubmed publisher
Anderson T, McCormick A, Smith S, Lowe D. Modeling antibody drug conjugate potential using a granzyme B antibody fusion protein. BMC Biol. 2024;22:66 pubmed publisher
Erol K, Hasabnis G, Altintas Z. A Novel NanoMIP-SPR Sensor for the Point-of-Care Diagnosis of Breast Cancer. Micromachines (Basel). 2023;14: pubmed publisher
Zhou J, Ge Q, Wang D, Guo Q, Tao Y. Engineering a modular double-transmembrane synthetic receptor system for customizing cellular programs. Cell Rep. 2023;42:112385 pubmed publisher
Ehsasatvatan M, Kohnehrouz B, Gholizadeh A, Ofoghi H, Shanehbandi D. The production of the first functional antibody mimetic in higher plants: the chloroplast makes the DARPin G3 for HER2 imaging in oncology. Biol Res. 2022;55:32 pubmed publisher
Li M, Zheng X, Shanker S, Jaroentomeechai T, Moeller T, Hulbert S, et al. Shotgun scanning glycomutagenesis: A simple and efficient strategy for constructing and characterizing neoglycoproteins. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Mester S, Evers M, Meyer S, Nilsen J, Greiff V, Sandlie I, et al. Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo. MAbs. 2021;13:1893888 pubmed publisher
Ding X, Gu W, Zhong Y, Hao X, Liu J, Xia S, et al. A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity. EBioMedicine. 2020;60:102996 pubmed publisher
Farràs M, Román R, Camps M, Miret J, Martinez O, Pujol X, et al. Heavy chain dimers stabilized by disulfide bonds are required to promote in vitro assembly of trastuzumab. BMC Mol Cell Biol. 2020;21:2 pubmed publisher
Wang X, Du D, Dong H, Song S, Koh K, Chen H. para-Sulfonatocalix[4]arene stabilized gold nanoparticles multilayers interfaced to electrodes through host-guest interaction for sensitive ErbB2 detection. Biosens Bioelectron. 2018;99:375-381 pubmed publisher
Vega J, Ramos J, Cruz V, Vicente Alique E, Sánchez Sánchez E, Sánchez Fernández A, et al. Molecular and hydrodynamic properties of human epidermal growth factor receptor HER2 extracellular domain and its homodimer: Experiments and multi-scale simulations. Biochim Biophys Acta Gen Subj. 2017;1861:2406-2416 pubmed publisher
Egan T, Diem D, Weldon R, Neumann T, Meyer S, Urech D. Novel multispecific heterodimeric antibody format allowing modular assembly of variable domain fragments. MAbs. 2017;9:68-84 pubmed publisher
Eletxigerra U, Martinez Perdiguero J, Barderas R, Pingarrón J, Campuzano S, Merino S. Surface plasmon resonance immunosensor for ErbB2 breast cancer biomarker determination in human serum and raw cancer cell lysates. Anal Chim Acta. 2016;905:156-62 pubmed publisher
Mayer W. Corneal transplants. Med Trial Tech Q. 1967;13:45-51 pubmed
image
image 1 :
Sino Biological 10004-HCCH image 1
product information
Catalog Number :
10004-HCCH
Product Name :
Human HER2 / ErbB2 Protein
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-cleavage
Size :
1 mg
List Price :
2316 USD
Gene ID :
NP_004439.2
Product Description :
A DNA sequence encoding the human ERBB2 (NP_004439.2) (Met1-Thr652) was expressed with five amino acids (DDDDK) at the C-terminus.
SpeciesSummary :
Human
ALTnames :
CD340,c-ERB2,c-ERB-2,HER2,HER-2,HER-2/neu,MLN 19,MLN-19,NEU,NGL,p185(erbB2),TKR1,VSCN2,MLN19
Purity :
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.