Human HER2 / ErbB2 Protein (Fc Tag) | Sino Biological 10004-H02H product information

product summary

company name :

Sino Biological

product type :

protein

product name :

Human HER2 / ErbB2 Protein (Fc Tag)

catalog :

10004-H02H

quantity :

1 mg

price :

1926 USD

more info or order :

Sino Biological product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
ELISA; human	Harth S, Ten Haaf A, Loew C, Frisch C, Knappik A. Generation by phage display and characterization of drug-target complex-specific antibodies for pharmacokinetic analysis of biotherapeutics. MAbs. 2019;11:178-190 pubmed publisher
ELISA; human	Longatti A, Schindler C, Collinson A, Jenkinson L, Matthews C, Fitzpatrick L, et al. High affinity single-chain variable fragments are specific and versatile targeting motifs for extracellular vesicles. Nanoscale. 2018;10:14230-14244 pubmed publisher
ELISA; human	Mizukami M, Onishi H, Hanagata H, Miyauchi A, Ito Y, Tokunaga H, et al. Efficient production of Trastuzumab Fab antibody fragments in Brevibacillus choshinensis expression system. Protein Expr Purif. 2018;150:109-118 pubmed publisher
	Wang Y, Zhang J, Han B, Tan L, Cai W, Li Y, et al. Noncanonical amino acids as doubly bio-orthogonal handles for one-pot preparation of protein multiconjugates. Nat Commun. 2023;14:974 pubmed publisher
	Ding X, Gu W, Zhong Y, Hao X, Liu J, Xia S, et al. A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity. EBioMedicine. 2020;60:102996 pubmed publisher
	Westerlund K, Vorobyeva A, Mitran B, Orlova A, Tolmachev V, Karlström A, et al. Site-specific conjugation of recognition tags to trastuzumab for peptide nucleic acid-mediated radionuclide HER2 pretargeting. Biomaterials. 2019;203:73-85 pubmed publisher
	SandersjÃ¶Ã¶ L, Jonsson A, LÃ¶fblom J. A new prodrug form of Affibody molecules (pro-Affibody) is selectively activated by cancer-associated proteases. Cell Mol Life Sci. 2015;72:1405-15 pubmed publisher
	Khalili H, Godwin A, Choi J, Lever R, Brocchini S. Comparative binding of disulfide-bridged PEG-Fabs. Bioconjug Chem. 2012;23:2262-77 pubmed publisher
	Liu Z, Duan J, Song Y, Ma J, Wang F, Lu X, et al. Novel HER2 aptamer selectively delivers cytotoxic drug to HER2-positive breast cancer cells in vitro. J Transl Med. 2012;10:148 pubmed publisher
	Vicente Alique E, Núñez Ramírez R, Vega J, Hu P, Martinez Salazar J. Size and conformational features of ErbB2 and ErbB3 receptors: a TEM and DLS comparative study. Eur Biophys J. 2011;40:835-42 pubmed publisher

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product information

Catalog Number :

10004-H02H

Product Name :

Human HER2 / ErbB2 Protein (Fc Tag)

Product Type :

Protein

Host Species :

HEK293 Cells

Conjugation :

C-human IgG1-Fc

Size :

1 mg

List Price :

1926 USD

Gene ID :

NP_004439.2

Product Description :

A DNA sequence encoding the extracellular domain (Met 1-Thr 652) of human ErbB2 (NP_004439.2) was fused with the Fc region of human IgG1 at the C-terminus.

SpeciesSummary :

Human

ALTnames :

CD340,c-ERB2,c-ERB-2,HER2,HER-2,HER-2/neu,MLN 19,MLN-19,NEU,NGL,p185(erbB2),TKR1,VSCN2,MLN19

Purity :

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC. ≥ 90 % as determined by SEC-MALS(Routinely tested).

Buffer :

Lyophilized from sterile PBS, pH 7.4.

Packaging :

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Storage :

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

more info or order :

Sino Biological product webpage