product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-β-Tubulin antibody produced in mouse
catalog :
T0198
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D66
reactivity :
great pond snail, human, mouse, rat, dogs, chicken, bovine
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
citations: 174
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 1c
Getz A, Xu F, Visser F, Persson R, Syed N. Tumor suppressor menin is required for subunit-specific nAChR α5 transcription and nAChR-dependent presynaptic facilitation in cultured mouse hippocampal neurons. Sci Rep. 2017;7:1768 pubmed publisher
  • western blot; great pond snail; 1:2000; fig 2
Getz A, Visser F, Bell E, Xu F, Flynn N, Zaidi W, et al. Two proteolytic fragments of menin coordinate the nuclear transcription and postsynaptic clustering of neurotransmitter receptors during synaptogenesis between Lymnaea neurons. Sci Rep. 2016;6:31779 pubmed publisher
  • western blot; mouse; fig 1
Li S, Qu Z, Haas M, Ngo L, Heo Y, Kang H, et al. The HSA21 gene EURL/C21ORF91 controls neurogenesis within the cerebral cortex and is implicated in the pathogenesis of Down Syndrome. Sci Rep. 2016;6:29514 pubmed publisher
  • western blot; mouse; fig 1
Wahl S, Magupalli V, Dembla M, Katiyar R, Schwarz K, Köblitz L, et al. The Disease Protein Tulp1 Is Essential for Periactive Zone Endocytosis in Photoreceptor Ribbon Synapses. J Neurosci. 2016;36:2473-93 pubmed publisher
  • western blot; human; fig 1
Le Pen J, Maillet L, Sarosiek K, Vuillier C, Gautier F, Montessuit S, et al. Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL. Cell Death Dis. 2016;7:e2083 pubmed publisher
  • western blot; rat; 1:5000; fig 2
Torres G, Morales P, García Miguel M, Norambuena Soto I, Cartes Saavedra B, Vidal Peña G, et al. Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation. Biochem Pharmacol. 2016;104:52-61 pubmed publisher
  • western blot; rat; fig s2
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed publisher
  • immunoprecipitation; human
Jamieson C, Lui C, Brocardo M, Martino Echarri E, Henderson B. Rac1 augments Wnt signaling by stimulating β-catenin-lymphoid enhancer factor-1 complex assembly independent of β-catenin nuclear import. J Cell Sci. 2015;128:3933-46 pubmed publisher
  • immunocytochemistry; rat; 1:1000
Zajkowski T, Nieznanska H, Nieznanski K. Stabilization of microtubular cytoskeleton protects neurons from toxicity of N-terminal fragment of cytosolic prion protein. Biochim Biophys Acta. 2015;1853:2228-39 pubmed publisher
  • western blot; rat; 1:10000
Tang N, Lyu D, Liu T, Chen F, Jing S, Hao T, et al. Different Effects of p52SHC1 and p52SHC3 on the Cell Cycle of Neurons and Neural Stem Cells. J Cell Physiol. 2016;231:172-80 pubmed publisher
  • western blot; human
Duvall Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed publisher
  • western blot; human; fig 7
Giehl K, Keller C, Muehlich S, Goppelt Struebe M. Actin-mediated gene expression depends on RhoA and Rac1 signaling in proximal tubular epithelial cells. PLoS ONE. 2015;10:e0121589 pubmed publisher
  • western blot; human; fig  3
Bi Q, Ranjan A, Fan R, Agarwal N, Welch D, Weinman S, et al. MTBP inhibits migration and metastasis of hepatocellular carcinoma. Clin Exp Metastasis. 2015;32:301-11 pubmed publisher
  • western blot; mouse; 1:4000
Tanti G, Goswami S. SG2NA recruits DJ-1 and Akt into the mitochondria and membrane to protect cells from oxidative damage. Free Radic Biol Med. 2014;75:1-13 pubmed publisher
  • immunocytochemistry; mouse
  • western blot; mouse
Asano S, Nemoto T, Kitayama T, Harada K, Zhang J, Harada K, et al. Phospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretion. Biol Open. 2014;3:463-74 pubmed publisher
  • western blot; rat
Heydendael W, Sengupta A, Beck S, Bhatnagar S. Optogenetic examination identifies a context-specific role for orexins/hypocretins in anxiety-related behavior. Physiol Behav. 2014;130:182-90 pubmed publisher
Sridharan S, Robeson M, Bastihalli Tukaramrao D, Howard C, Subramaniyan B, Tilley A, et al. Targeting of the Eukaryotic Translation Initiation Factor 4A Against Breast Cancer Stemness. Front Oncol. 2019;9:1311 pubmed publisher
Zivanović J, Kouroussis E, Kohl J, Adhikari B, Bursać B, Schott Roux S, et al. Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration. Cell Metab. 2019;30:1152-1170.e13 pubmed publisher
Tarumoto Y, Lin S, Wang J, Milazzo J, Xu Y, Lu B, et al. Salt-Inducible Kinase inhibition suppresses acute myeloid leukemia progression in vivo. Blood. 2019;: pubmed publisher
Roy A, Ghosh A, Kumar B, Chandran B. IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP. elife. 2019;8: pubmed publisher
Kolba M, Dudka W, Zareba Kozioł M, Kominek A, Ronchi P, Turos L, et al. Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells. Cell Death Dis. 2019;10:817 pubmed publisher
Ito C, Akutsu H, Yao R, Yoshida K, Yamatoya K, Mutoh T, et al. Odf2 haploinsufficiency causes a new type of decapitated and decaudated spermatozoa, Odf2-DDS, in mice. Sci Rep. 2019;9:14249 pubmed publisher
Asano S, Ikura Y, Nishimoto M, Yamawaki Y, Hamao K, Kamijo K, et al. Phospholipase C-related catalytically inactive protein regulates cytokinesis by protecting phosphatidylinositol 4,5-bisphosphate from metabolism in the cleavage furrow. Sci Rep. 2019;9:12729 pubmed publisher
Cockman E, Narayan V, Willard B, Shetty S, Copeland P, Driscoll D. Identification of the Selenoprotein S Positive UGA Recoding (SPUR) element and its position-dependent activity. RNA Biol. 2019;16:1682-1696 pubmed publisher
Rajah A, Boudreau C, Ilie A, Wee T, Tang K, Borisov A, et al. Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX. Sci Rep. 2019;9:11430 pubmed publisher
Poletto Bonetto J, Fernandes R, Dartora D, Flahault A, Sonea A, He Y, et al. Impact of early life AT1 blockade on adult cardiac morpho-functional changes and the renin-angiotensin system in a model of neonatal high oxygen-induced cardiomyopathy. Eur J Pharmacol. 2019;860:172585 pubmed publisher
Diao H, Cheng N, Zhao Y, Xu H, Dong H, Thamm D, et al. Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling. BMC Vet Res. 2019;15:276 pubmed publisher
Staicu F, López Úbeda R, Romero Aguirregomezcorta J, Martinez Soto J, Matás Parra C. Regulation of boar sperm functionality by the nitric oxide synthase/nitric oxide system. J Assist Reprod Genet. 2019;36:1721-1736 pubmed publisher
Bonadeo N, Becu Villalobos D, Cristina C, Lacau Mengido I. The Notch system during pubertal development of the bovine mammary gland. Sci Rep. 2019;9:8899 pubmed publisher
Howard C, Bearss N, Subramaniyan B, Tilley A, Sridharan S, Villa N, et al. The CXCR4-LASP1-eIF4F Axis Promotes Translation of Oncogenic Proteins in Triple-Negative Breast Cancer Cells. Front Oncol. 2019;9:284 pubmed publisher
Moon J, Oh S, Lee C, Chi S, Kim H. TGF-β1 protects colon tumor cells from apoptosis through XAF1 suppression. Int J Oncol. 2019;54:2117-2126 pubmed publisher
Ramis G, Villalonga Planells R, Serra Sitjar M, Brell M, Fernandez De Mattos S, Villalonga P. The tumor suppressor FOXO3a mediates the response to EGFR inhibition in glioblastoma cells. Cell Oncol (Dordr). 2019;: pubmed publisher
Soriano Úbeda C, Romero Aguirregomezcorta J, Matas C, Visconti P, García Vázquez F. Manipulation of bicarbonate concentration in sperm capacitation media improvesin vitro fertilisation output in porcine species. J Anim Sci Biotechnol. 2019;10:19 pubmed publisher
Owa M, Uchihashi T, Yanagisawa H, Yamano T, Iguchi H, Fukuzawa H, et al. Inner lumen proteins stabilize doublet microtubules in cilia and flagella. Nat Commun. 2019;10:1143 pubmed publisher
Zhang B, Wu X, Liu J, Song L, Song Q, Wang L, et al. β-Actin: Not a Suitable Internal Control of Hepatic Fibrosis Caused by Schistosoma japonicum. Front Microbiol. 2019;10:66 pubmed publisher
Theka I, Sottile F, Cammisa M, Bonnin S, Sánchez Delgado M, Di Vicino U, et al. Wnt/β-catenin signaling pathway safeguards epigenetic stability and homeostasis of mouse embryonic stem cells. Sci Rep. 2019;9:948 pubmed publisher
Goyama S, Schibler J, Mulloy J. Alternative translation initiation generates the N-terminal truncated form of RUNX1 that retains hematopoietic activity. Exp Hematol. 2019;72:27-35 pubmed publisher
Natarajan A, Smith A, Berry B, Lambert S, Molnar P, Hickman J. Temporal Characterization of Neuronal Migration Behavior on Chemically Patterned Neuronal Circuits in a Defined in Vitro Environment. ACS Biomater Sci Eng. 2018;4:3460-3470 pubmed publisher
Mondaca Ruff D, Riquelme J, Quiroga C, Norambuena Soto I, Sanhueza Olivares F, Villar Fincheira P, et al. Angiotensin II-Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy. Front Pharmacol. 2018;9:1553 pubmed publisher
Twomey J, Zhao L, Luo S, Xu Q, Zhang B. Tubulin couples death receptor 5 to regulate apoptosis. Oncotarget. 2018;9:36804-36815 pubmed publisher
Platnich J, Chung H, Lau A, Sandall C, Bondzi Simpson A, Chen H, et al. Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome. Cell Rep. 2018;25:1525-1536.e7 pubmed publisher
Swearman H, Koustas G, Knight E, Liperis G, Grupen C, Sjoblom C. pH: the silent variable significantly impacting meiotic spindle assembly in mouse oocytes. Reprod Biomed Online. 2018;37:279-290 pubmed publisher
Yamaguchi K, Shioda N, Yabuki Y, Zhang C, Han F, Fukunaga K. SA4503, A Potent Sigma-1 Receptor Ligand, Ameliorates Synaptic Abnormalities and Cognitive Dysfunction in a Mouse Model of ATR-X Syndrome. Int J Mol Sci. 2018;19: pubmed publisher
Saha A, Tiwari S, Dharmarajan S, Otteson D, Belecky Adams T. Class I histone deacetylases in retinal progenitors and differentiating ganglion cells. Gene Expr Patterns. 2018;30:37-48 pubmed publisher
Ogiwara I, Miyamoto H, Tatsukawa T, Yamagata T, Nakayama T, Atapour N, et al. Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice. Commun Biol. 2018;1: pubmed publisher
Zubeldia Brenner L, De Winne C, Perrone S, Rodriguez Segui S, Willems C, Ornstein A, et al. Inhibition of Notch signaling attenuates pituitary adenoma growth in nude mice. Endocr Relat Cancer. 2018;: pubmed publisher
Wei C, Yang L, Cheng J, Imani S, Fu S, Lv H, et al. A novel homozygous variant of GPR98 causes usher syndrome type IIC in a consanguineous Chinese family by next generation sequencing. BMC Med Genet. 2018;19:99 pubmed publisher
Lau A, Chung H, Komada T, Platnich J, Sandall C, Choudhury S, et al. Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury. J Clin Invest. 2018;128:2894-2913 pubmed publisher
Kumar D, New J, Vishwakarma V, Joshi R, Enders J, Lin F, et al. Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression. Cancer Res. 2018;78:3769-3782 pubmed publisher
Zirkel A, Nikolic M, Sofiadis K, Mallm J, Brackley C, Gothe H, et al. HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types. Mol Cell. 2018;70:730-744.e6 pubmed publisher
Li H, Zhao H, Hao S, Shang L, Wu J, Song C, et al. Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts. Sci Rep. 2018;8:5118 pubmed publisher
Brooks C, Murphy J, Belcastro M, Heller D, Kolandaivelu S, KISSELEV O, et al. Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors. Front Mol Neurosci. 2018;11:16 pubmed publisher
Xu D, Li Y, Wu L, Li Y, Zhao D, Yu J, et al. Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions. J Cell Biol. 2018;217:975-995 pubmed publisher
Beltramo E, Arroba A, Mazzeo A, Valverde A, Porta M. Imbalance between pro-apoptotic and pro-survival factors in human retinal pericytes in diabetic-like conditions. Acta Ophthalmol. 2018;96:e19-e26 pubmed publisher
Lee A, Rayner S, De Luca A, Gwee S, Morsch M, Sundaramoorthy V, et al. Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex. Open Biol. 2017;7: pubmed publisher
Sheng Y, Chen X, Hou X, Yuan X, Yuan B, Yuan Y, et al. Urate promotes SNCA/α-synuclein clearance via regulating mTOR-dependent macroautophagy. Exp Neurol. 2017;297:138-147 pubmed publisher
Osuru H, Pramoonjago P, Abhyankar M, Swanson E, Roker L, Cathro H, et al. Immunolocalization of TAR DNA-binding protein of 43?kDa (TDP-43) in mouse seminiferous epithelium. Mol Reprod Dev. 2017;84:675-685 pubmed publisher
Belayachi L, Aceves Luquero C, Merghoub N, de Mattos S, Amzazi S, Villalonga P, et al. INDUCTION OF CELL CYCLE ARREST AND APOPTOSIS BY ORMENIS ERIOLEPIS A MORROCAN ENDEMIC PLANT IN VARIOUS HUMAN CANCER CELL LINES. Afr J Tradit Complement Altern Med. 2017;14:356-373 pubmed publisher
van Andel H, Ren Z, Koopmans I, Joosten S, Kocemba K, de Lau W, et al. Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins. Proc Natl Acad Sci U S A. 2017;114:376-381 pubmed publisher
Yang K, Wang M, Zhao Y, Sun X, Yang Y, Li X, et al. A redox mechanism underlying nucleolar stress sensing by nucleophosmin. Nat Commun. 2016;7:13599 pubmed publisher
Alecu I, Tedeschi A, Behler N, Wunderling K, Lamberz C, Lauterbach M, et al. Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction. J Lipid Res. 2017;58:42-59 pubmed publisher
Musinova Y, Lisitsyna O, Sorokin D, Arifulin E, Smirnova T, Zinovkin R, et al. RNA-dependent disassembly of nuclear bodies. J Cell Sci. 2016;129:4509-4520 pubmed
Goyama S, Shrestha M, Schibler J, Rosenfeldt L, Miller W, O BRIEN E, et al. Protease-activated receptor-1 inhibits proliferation but enhances leukemia stem cell activity in acute myeloid leukemia. Oncogene. 2017;36:2589-2598 pubmed publisher
Samson A, Ho B, Au A, Schoenwaelder S, Smyth M, Bottomley S, et al. Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells. Open Biol. 2016;6: pubmed
Kumar B, Dutta D, Iqbal J, Ansari M, Roy A, Chikoti L, et al. ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus. PLoS Pathog. 2016;12:e1005960 pubmed publisher
Gutiérrez Franco A, Eixarch H, Costa C, Gil V, Castillo M, Calvo Barreiro L, et al. Semaphorin 7A as a Potential Therapeutic Target for Multiple Sclerosis. Mol Neurobiol. 2017;54:4820-4831 pubmed publisher
Barquilla A, Lamberto I, Noberini R, Heynen Genel S, Brill L, Pasquale E. Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylation. Mol Biol Cell. 2016;27:2757-70 pubmed publisher
Bullova P, Cougnoux A, Abunimer L, Kopacek J, Pastorekova S, Pacak K. Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models. Oncotarget. 2016;7:40531-40545 pubmed publisher
Yen B, Basler C. Effects of Filovirus Interferon Antagonists on Responses of Human Monocyte-Derived Dendritic Cells to RNA Virus Infection. J Virol. 2016;90:5108-5118 pubmed publisher
Bertagnolli M, Dios A, Béland Bonenfant S, Gascon G, Sutherland M, Lukaszewski M, et al. Activation of the Cardiac Renin-Angiotensin System in High Oxygen-Exposed Newborn Rats: Angiotensin Receptor Blockade Prevents the Developmental Programming of Cardiac Dysfunction. Hypertension. 2016;67:774-82 pubmed publisher
Lee M, Jeong S, Ko K, Park S, Ryu B, Kim I, et al. RASSF1A Directly Antagonizes RhoA Activity through the Assembly of a Smurf1-Mediated Destruction Complex to Suppress Tumorigenesis. Cancer Res. 2016;76:1847-59 pubmed publisher
Rinschen M, Bharill P, Wu X, Kohli P, Reinert M, Kretz O, et al. The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes. Hum Mol Genet. 2016;25:1328-44 pubmed publisher
Bartram M, Habbig S, Pahmeyer C, Höhne M, Weber L, Thiele H, et al. Three-layered proteomic characterization of a novel ACTN4 mutation unravels its pathogenic potential in FSGS. Hum Mol Genet. 2016;25:1152-64 pubmed publisher
Sin T, Yung B, Yip S, Chan L, Wong C, Tam E, et al. SIRT1-dependent myoprotective effects of resveratrol on muscle injury induced by compression. Front Physiol. 2015;6:293 pubmed publisher
Kopecki Z, Yang G, Jackson J, Melville E, Calley M, Murrell D, et al. Cytoskeletal protein Flightless I inhibits apoptosis, enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progression. Oncotarget. 2015;6:36426-40 pubmed publisher
Sin T, Tam B, Yu A, Yip S, Yung B, Chan L, et al. Acute Treatment of Resveratrol Alleviates Doxorubicin-Induced Myotoxicity in Aged Skeletal Muscle Through SIRT1-Dependent Mechanisms. J Gerontol A Biol Sci Med Sci. 2016;71:730-9 pubmed publisher
Huang Z, Kataoka M, Chen J, Wu G, Ding J, Nie M, et al. Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis. J Clin Invest. 2015;125:4122-34 pubmed publisher
Axelsen L, Calloe K, Braunstein T, Riemann M, Hofgaard J, Liang B, et al. Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis. Cardiovasc Diabetol. 2015;14:87 pubmed publisher
Choi H, Gillespie D, Berg S, Rice C, Couldwell S, Gu J, et al. Intermittent induction of HIF-1α produces lasting effects on malignant progression independent of its continued expression. PLoS ONE. 2015;10:e0125125 pubmed publisher
Uribe Lewis S, Stark R, Carroll T, Dunning M, Bachman M, Ito Y, et al. 5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer. Genome Biol. 2015;16:69 pubmed publisher
Sin T, Tam B, Yung B, Yip S, Chan L, Wong C, et al. Resveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis. J Physiol. 2015;593:1887-99 pubmed publisher
Izzo F, Mercogliano F, Venturutti L, Tkach M, Inurrigarro G, Schillaci R, et al. Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. Breast Cancer Res. 2014;16:491 pubmed publisher
Goyal U, Renvoisé B, Chang J, Blackstone C. Spastin-interacting protein NA14/SSNA1 functions in cytokinesis and axon development. PLoS ONE. 2014;9:e112428 pubmed publisher
Yen B, Mulder L, Martinez O, Basler C. Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation. J Virol. 2014;88:12500-10 pubmed publisher
Tiwari S, Dharmarajan S, Shivanna M, Otteson D, Belecky Adams T. Histone deacetylase expression patterns in developing murine optic nerve. BMC Dev Biol. 2014;14:30 pubmed publisher
De Joussineau C, Sahut Barnola I, Tissier F, Dumontet T, Drelon C, Batisse Lignier M, et al. mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD). Hum Mol Genet. 2014;23:5418-28 pubmed publisher
Farazi T, Leonhardt C, Mukherjee N, Mihailovic A, Li S, Max K, et al. Identification of the RNA recognition element of the RBPMS family of RNA-binding proteins and their transcriptome-wide mRNA targets. RNA. 2014;20:1090-102 pubmed publisher
Sinha S, Belcastro M, Datta P, Seo S, Sokolov M. Essential role of the chaperonin CCT in rod outer segment biogenesis. Invest Ophthalmol Vis Sci. 2014;55:3775-85 pubmed publisher
Gratas C, Séry Q, Rabé M, Oliver L, Vallette F. Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma. Oncotarget. 2014;5:2428-35 pubmed
Rojas Fernandez A, Plechanovová A, Hattersley N, Jaffray E, Tatham M, Hay R. SUMO chain-induced dimerization activates RNF4. Mol Cell. 2014;53:880-92 pubmed publisher
Sin T, Yu A, Yung B, Yip S, Chan L, Wong C, et al. Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart. J Physiol. 2014;592:2535-48 pubmed publisher
Belayachi L, Aceves Luquero C, Merghoub N, Bakri Y, Fernandez De Mattos S, Amzazi S, et al. Retama monosperma n-hexane extract induces cell cycle arrest and extrinsic pathway-dependent apoptosis in Jurkat cells. BMC Complement Altern Med. 2014;14:38 pubmed publisher
Ogiwara I, Iwasato T, Miyamoto H, Iwata R, Yamagata T, Mazaki E, et al. Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome. Hum Mol Genet. 2013;22:4784-804 pubmed publisher
Karagianni F, Prakoura N, Kaltsa G, Politis P, Arvaniti E, Kaltezioti V, et al. Transgelin Up-Regulation in Obstructive Nephropathy. PLoS ONE. 2013;8:e66887 pubmed publisher
Xu F, Piett C, Farkas S, Qazzaz M, Syed N. Silver nanoparticles (AgNPs) cause degeneration of cytoskeleton and disrupt synaptic machinery of cultured cortical neurons. Mol Brain. 2013;6:29 pubmed publisher
Johnson M, Sharma M, Mok M, Henderson B. Stimulation of in vivo nuclear transport dynamics of actin and its co-factors IQGAP1 and Rac1 in response to DNA replication stress. Biochim Biophys Acta. 2013;1833:2334-47 pubmed publisher
Morrison J, Laurent Rolle M, Maestre A, Rajsbaum R, Pisanelli G, Simon V, et al. Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling. PLoS Pathog. 2013;9:e1003265 pubmed publisher
Incontro S, Ciruela F, ZIFF E, Hofmann F, Sánchez Prieto J, Torres M. The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma membrane of developing cerebellar granule cells. Biochim Biophys Acta. 2013;1833:1820-31 pubmed publisher
Hsu C, Hu C. Transcriptional activity of c-Jun is critical for the suppression of AR function. Mol Cell Endocrinol. 2013;372:12-22 pubmed publisher
Bertin Ciftci J, Barre B, Le Pen J, Maillet L, Couriaud C, Juin P, et al. pRb/E2F-1-mediated caspase-dependent induction of Noxa amplifies the apoptotic effects of the Bcl-2/Bcl-xL inhibitor ABT-737. Cell Death Differ. 2013;20:755-64 pubmed publisher
Bett J, Ibrahim A, Garg A, Kelly V, Pedrioli P, Rocha S, et al. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. Biochem J. 2013;451:185-94 pubmed publisher
Kim K, Lee K, Rhee K. CEP90 is required for the assembly and centrosomal accumulation of centriolar satellites, which is essential for primary cilia formation. PLoS ONE. 2012;7:e48196 pubmed publisher
Sinha S, Majumder A, Belcastro M, Sokolov M, Artemyev N. Expression and subcellular distribution of UNC119a, a protein partner of transducin ? subunit in rod photoreceptors. Cell Signal. 2013;25:341-8 pubmed publisher
Paschou M, Doxakis E. Neurofibromin 1 is a miRNA target in neurons. PLoS ONE. 2012;7:e46773 pubmed publisher
Samson A, Knaupp A, Sashindranath M, Borg R, Au A, Cops E, et al. Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin. Cell Rep. 2012;2:889-901 pubmed publisher
Habbig S, Bartram M, Sägmüller J, Griessmann A, Franke M, Muller R, et al. The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. Hum Mol Genet. 2012;21:5528-38 pubmed publisher
Lee S, Chang J, Renvoisé B, Tipirneni A, Yang S, Blackstone C. MITD1 is recruited to midbodies by ESCRT-III and participates in cytokinesis. Mol Biol Cell. 2012;23:4347-61 pubmed publisher
Xu F, Farkas S, Kortbeek S, Zhang F, Chen L, Zamponi G, et al. Mercury-induced toxicity of rat cortical neurons is mediated through N-Methyl-D-Aspartate receptors. Mol Brain. 2012;5:30 pubmed publisher
Johnson M, Henderson B. The scaffolding protein IQGAP1 co-localizes with actin at the cytoplasmic face of the nuclear envelope: implications for cytoskeletal regulation. Bioarchitecture. 2012;2:138-42 pubmed publisher
Seibenhener M, Wooten M. Isolation and culture of hippocampal neurons from prenatal mice. J Vis Exp. 2012;: pubmed publisher
Ramis G, Thomàs Moyà E, Fernandez De Mattos S, Rodriguez J, Villalonga P. EGFR inhibition in glioma cells modulates Rho signaling to inhibit cell motility and invasion and cooperates with temozolomide to reduce cell growth. PLoS ONE. 2012;7:e38770 pubmed publisher
Renvoisé B, Stadler J, Singh R, Bakowska J, Blackstone C. Spg20-/- mice reveal multimodal functions for Troyer syndrome protein spartin in lipid droplet maintenance, cytokinesis and BMP signaling. Hum Mol Genet. 2012;21:3604-18 pubmed publisher
Belcastro M, Song H, Sinha S, Song C, Mathers P, Sokolov M. Phosphorylation of phosducin accelerates rod recovery from transducin translocation. Invest Ophthalmol Vis Sci. 2012;53:3084-91 pubmed publisher
Mok M, Henderson B. The in vivo dynamic organization of BRCA1-A complex proteins at DNA damage-induced nuclear foci. Traffic. 2012;13:800-14 pubmed publisher
Agarwal N, Adhikari A, Iyer S, Hekmatdoost K, Welch D, Iwakuma T. MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4. Oncogene. 2013;32:462-70 pubmed publisher
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product information
Product No. :
T0198
Product Name :
Monoclonal Anti-β-Tubulin antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
D66
Applications/Description :
Suitable for immunocytochemistry (3% paraformaldehyde-0.5% Triton X-100 and methanol-acetone); western blot: 0.5-1.0 μg/mL using whole extract of cultured rat adrenal pheochromocytoma (PC-12) cells; indirect ELISA; immunoprecipitation (IP)
Species Reactivity :
monkey, Oxyrrhis marina (dinoflagellate), rat, mouse, chicken, sea urchin (Lytechinus pictus and Paracentrotus lividus), rabbit, canine, Chlamydomonas reinhardtii, human, bovine, hamster
Isotype :
IgG1
Concentration :
~1 mg/mL
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA