DNA Binding Protein-7 (DBP-7), recombinant | MilliporeSigma SRP7603 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MilliporeSigma

other brands :

FLUKA, Sigma-Aldrich, Roche Applied Science

product type :

chemical

product name :

DNA Binding Protein-7 (DBP-7), recombinant

catalog :

SRP7603

product information

name :

DNA Binding Protein-7 (DBP-7), recombinant

cat no :

SRP7603

brand :

SIGMA

prod type :

Chemical

name suffix :

recombinant, expressed in E. coli, >=99% (SDS-PAGE)

storage temp :

-20C

storage :

-20C

physical form :

Sterile filtered and Lyophilized without additives.

shipped in :

wet ice

general description :

DNA Binding Protein-7 (DBP-7) is a N-terminal His-tagged recombinant protein and a member of the Sso7d family of small, abundant, non-specific DNA-binding proteins from the hyperthermophilic Archea Sulfolobus. The 7-kDa protein from Sulfolobus spp. consists of a five stranded, incomplete beta-barrel capped at the opening by a C-terminal alpha-helix; they bind to the minor groove of a DNA duplex via the triple-stranded beta-sheet. The topology of the Sulfolobus 7-kDa proteins was found to be similar to that of chromatin organization modifier (chromo) domains and eukaryotic SH3 domains, which are involved in protein-protein interactions. In vitro studies have shown that DBP-7 promotes the annealing of complementary DNA strands, induces negative supercoiling and chaperones the disassembly and renaturation of protein aggregates in an ATP hydrolysis-dependent manner.

ncbi accession no :

P39476

form :

lyophilized

syns :

DNA Binding Protein 7

mol wt :

mol wt ~9.4 kDa