product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Ryanodine Receptor antibody produced in mouse
catalog :
R129
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
34C
reactivity :
human, mouse, rat, dogs, chicken, bovine
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 3f
Hostrup M, Kalsen A, Onslev J, Jessen S, Haase C, Habib S, et al. Mechanisms underlying enhancements in muscle force and power output during maximal cycle ergometer exercise induced by chronic β2-adrenergic stimulation in men. J Appl Physiol (1985). 2015;119:475-86 pubmed publisher
Kelu J, Webb S, Galione A, Miller A. TPC2-mediated Ca2+ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons. Dev Biol. 2018;438:57-68 pubmed publisher
Bennett A, O Donohue M, Gundry S, Chan A, Widrick J, Draper I, et al. RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes. PLoS Genet. 2018;14:e1007226 pubmed publisher
Stephens J, Schiemann A, Roesl C, Miller D, Massey S, Pollock N, et al. Functional analysis of RYR1 variants linked to malignant hyperthermia. Temperature (Austin). 2016;3:328-339 pubmed
Murayama T, Kurebayashi N, Yamazawa T, Oyamada H, Suzuki J, Kanemaru K, et al. Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region. PLoS ONE. 2015;10:e0130606 pubmed publisher
Kerr J, Ziman A, Mueller A, Muriel J, Kleinhans Welte E, Gumerson J, et al. Dysferlin stabilizes stress-induced Ca2+ signaling in the transverse tubule membrane. Proc Natl Acad Sci U S A. 2013;110:20831-6 pubmed publisher
Scorzeto M, Giacomello M, Toniolo L, Canato M, Blaauw B, Paolini C, et al. Mitochondrial Ca2+-handling in fast skeletal muscle fibers from wild type and calsequestrin-null mice. PLoS ONE. 2013;8:e74919 pubmed publisher
Amoasii L, Hnia K, Chicanne G, Brech A, Cowling B, Müller M, et al. Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo. J Cell Sci. 2013;126:1806-19 pubmed publisher
Pierson C, Dulin Smith A, Durban A, Marshall M, Marshall J, Snyder A, et al. Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotype. Hum Mol Genet. 2012;21:811-25 pubmed publisher
Durieux A, Vignaud A, Prudhon B, Viou M, Beuvin M, Vassilopoulos S, et al. A centronuclear myopathy-dynamin 2 mutation impairs skeletal muscle structure and function in mice. Hum Mol Genet. 2010;19:4820-36 pubmed publisher
Iketani M, Imaizumi C, Nakamura F, Jeromin A, Mikoshiba K, Goshima Y, et al. Regulation of neurite outgrowth mediated by neuronal calcium sensor-1 and inositol 1,4,5-trisphosphate receptor in nerve growth cones. Neuroscience. 2009;161:743-52 pubmed publisher
Jeffrey J, Aspden R. Cyclooxygenase inhibition lowers prostaglandin E2 release from articular cartilage and reduces apoptosis but not proteoglycan degradation following an impact load in vitro. Arthritis Res Ther. 2007;9:R129 pubmed
Airey J, Beck C, Murakami K, Tanksley S, Deerinck T, Ellisman M, et al. Identification and localization of two triad junctional foot protein isoforms in mature avian fast twitch skeletal muscle. J Biol Chem. 1990;265:14187-94 pubmed
product information
Product No. :
R129
Product Name :
Monoclonal Anti-Ryanodine Receptor antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
34C
Applications/Description :
Suitable for direct immunofluorescence; western blot: 1:5,000; immunoprecipitation (IP); immunohistochemistry (frozen sections): 1:1,000
Species Reactivity :
sheep, human, rat, primate, mouse, chicken, rabbit, canine, mink, fish, frog, bovine
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA