| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; fig 3
- immunohistochemistry - frozen section; mouse; fig 6
- western blot; human; fig 2
| Vanderperre B, Cermakova K, Escoffier J, Kaba M, Bender T, Nef S, et al. MPC1-like Is a Placental Mammal-specific Mitochondrial Pyruvate Carrier Subunit Expressed in Postmeiotic Male Germ Cells. J Biol Chem. 2016;291:16448-61 pubmed publisher |
- western blot knockout validation; mouse; loading ...; fig 1e
| Vanderperre B, Herzig S, Krznar P, Hörl M, Ammar Z, Montessuit S, et al. Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet. PLoS Genet. 2016;12:e1006056 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig e2d
| Choi J, Sebastian C, Ferrer C, Lewis C, Sade Feldman M, LaSalle T, et al. A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma. Nat Metab. 2021;3:182-195 pubmed publisher |
- immunocytochemistry; human; 1:500; loading ...; fig 1a
- western blot; human; 1:1000; loading ...; fig 1b
| Li Y, Li X, Kan Q, Zhang M, Li X, Xu R, et al. Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas. Oncotarget. 2017;8:1058-1073 pubmed publisher |
- western blot; mouse; loading ...; fig 3e
| Lacroix M, Rodier G, Kirsh O, Houles T, Delpech H, Seyran B, et al. E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity. Proc Natl Acad Sci U S A. 2016;113:10998-1003 pubmed publisher |
| Zhu H, Wan H, Wu L, Li Q, Liu S, Duan S, et al. Mitochondrial pyruvate carrier: a potential target for diabetic nephropathy. BMC Nephrol. 2020;21:274 pubmed publisher |
| Rossi A, Rigotto G, Valente G, Giorgio V, Basso E, Filadi R, et al. Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer's Disease-Related Models. Cell Rep. 2020;30:2332-2348.e10 pubmed publisher |
| Burrell J, Richard A, King W, Stephens J. Mitochondrial Pyruvate Carriers are not Required for Adipogenesis but are Regulated by High-Fat Feeding in Brown Adipose Tissue. Obesity (Silver Spring). 2020;28:293-302 pubmed publisher |
| Varuzhanyan G, Rojansky R, Sweredoski M, Graham R, Hess S, Ladinsky M, et al. Mitochondrial fusion is required for spermatogonial differentiation and meiosis. elife. 2019;8: pubmed publisher |
| Zou H, Chen Q, Zhang A, Wang S, Wu H, Yuan Y, et al. MPC1 deficiency accelerates lung adenocarcinoma progression through the STAT3 pathway. Cell Death Dis. 2019;10:148 pubmed publisher |
| Flores A, Sandoval Gonzalez S, Takahashi R, Krall A, Sathe L, Wei L, et al. Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin. Nat Commun. 2019;10:91 pubmed publisher |
| Tang X, Chen Q, Li Y, Wang Y, Zou H, Fu W, et al. Mitochondrial pyruvate carrier 1 functions as a tumor suppressor and predicts the prognosis of human renal cell carcinoma. Lab Invest. 2019;99:191-199 pubmed publisher |
| Liu X, Cooper D, Cluntun A, Warmoes M, Zhao S, Reid M, et al. Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals. Cell. 2018;175:502-513.e13 pubmed publisher |
| Ma X, Cui Y, Zhou H, Li Q. Function of mitochondrial pyruvate carriers in hepatocellular carcinoma patients. Oncol Lett. 2018;15:9110-9116 pubmed publisher |
| Xie H, Zhu S, Zhang J, Wen J, Yuan H, Pan L, et al. Glucose metabolism during in vitro maturation of mouse oocytes: An study using RNA interference. J Cell Physiol. 2018;233:6952-6964 pubmed publisher |
| Ohashi T, Eguchi H, Kawamoto K, Konno M, Asai A, Colvin H, et al. Mitochondrial pyruvate carrier modulates the epithelial-mesenchymal transition in cholangiocarcinoma. Oncol Rep. 2018;39:1276-1282 pubmed publisher |
| Chen Y, McCommis K, Ferguson D, Hall A, Harris C, Finck B. Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid. Endocrinology. 2017;: pubmed publisher |
| Zhou X, Xiong Z, Xiao S, Zhou J, Ding Z, Tang L, et al. Overexpression of MPC1 inhibits the proliferation, migration, invasion, and stem cell-like properties of gastric cancer cells. Onco Targets Ther. 2017;10:5151-5163 pubmed publisher |
| Yang X, Wang H, Huang C, He X, Xu W, Luo Y, et al. Zinc enhances the cellular energy supply to improve cell motility and restore impaired energetic metabolism in a toxic environment induced by OTA. Sci Rep. 2017;7:14669 pubmed publisher |
| Schell J, Wisidagama D, Bensard C, Zhao H, Wei P, Tanner J, et al. Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. Nat Cell Biol. 2017;19:1027-1036 pubmed publisher |
| Flores A, Schell J, Krall A, Jelinek D, Miranda M, Grigorian M, et al. Lactate dehydrogenase activity drives hair follicle stem cell activation. Nat Cell Biol. 2017;19:1017-1026 pubmed publisher |
| Shannon C, Daniele G, Galindo C, Abdul Ghani M, DeFronzo R, Norton L. Pioglitazone inhibits mitochondrial pyruvate metabolism and glucose production in hepatocytes. FEBS J. 2017;284:451-465 pubmed publisher |
| Compan V, Pierredon S, Vanderperre B, Krznar P, Marchiq I, Zamboni N, et al. Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect. Mol Cell. 2015;59:491-501 pubmed publisher |
