product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-KDM5B antibody produced in rabbit
catalog :
HPA027179
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot knockout validation
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig 1
  • western blot knockout validation; human; fig 1
Cao J, Wu L, Zhang S, Lu M, Cheung W, Cai W, et al. An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting. Nucleic Acids Res. 2016;44:e149 pubmed
Liu X, Zhang S, McGeary M, Krykbaeva I, Lai L, Jansen D, et al. KDM5B Promotes Drug Resistance by Regulating Melanoma-Propagating Cell Subpopulations. Mol Cancer Ther. 2019;18:706-717 pubmed publisher
Wu L, Cao J, Cai W, Lang S, Horton J, Jansen D, et al. KDM5 histone demethylases repress immune response via suppression of STING. PLoS Biol. 2018;16:e2006134 pubmed publisher
Szarc vel Szic K, Declerck K, Crans R, Diddens J, Scherf D, Gerhäuser C, et al. Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A. Oncotarget. 2017;8:40434-40453 pubmed publisher
Gale M, Sayegh J, Cao J, Norcia M, Gareiss P, Hoyer D, et al. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance. Oncotarget. 2016;7:39931-39944 pubmed publisher
Fork C, Gu L, Hitzel J, Josipovic I, Hu J, SzeKa Wong M, et al. Epigenetic Regulation of Angiogenesis by JARID1B-Induced Repression of HOXA5. Arterioscler Thromb Vasc Biol. 2015;35:1645-52 pubmed publisher
Wang L, Mao Y, Du G, He C, Han S. Overexpression of JARID1B is associated with poor prognosis and chemotherapy resistance in epithelial ovarian cancer. Tumour Biol. 2015;36:2465-72 pubmed publisher
product information
Product No. :
HPA027179
Product Name :
Anti-KDM5B antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for immunohistochemistry: 1:200- 1:500
Species Reactivity :
human
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA