This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-MYO10 antibody produced in rabbit
catalog :
HPA024223
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot knockout validation
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 1c
Heimsath E, Yim Y, Mustapha M, Hammer J, Cheney R. Myosin-X knockout is semi-lethal and demonstrates that myosin-X functions in neural tube closure, pigmentation, hyaloid vasculature regression, and filopodia formation. Sci Rep. 2017;7:17354 pubmed publisher
Balta E, Hardt R, Liang J, Kirchgessner H, Orlik C, Jahraus B, et al. Spatial oxidation of L-plastin downmodulates actin-based functions of tumor cells. Nat Commun. 2019;10:4073 pubmed publisher
So C, Seres K, Steyer A, Mönnich E, Clift D, Pejkovska A, et al. A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes. Science. 2019;364: pubmed publisher
Sun Y, Yang Y, Keller K. Myosin-X Silencing in the Trabecular Meshwork Suggests a Role for Tunneling Nanotubes in Outflow Regulation. Invest Ophthalmol Vis Sci. 2019;60:843-851 pubmed publisher
Bachg A, Horsthemke M, Skryabin B, Klasen T, Nagelmann N, Faber C, et al. Phenotypic analysis of Myo10 knockout (Myo10tm2/tm2) mice lacking full-length (motorized) but not brain-specific headless myosin X. Sci Rep. 2019;9:597 pubmed publisher
Wang B, Pan J, Yu H, Xiong L, Zhao K, Xiong S, et al. Lack of Myosin X Enhances Osteoclastogenesis and Increases Cell Surface Unc5b in Osteoclast-Lineage Cells. J Bone Miner Res. 2019;34:939-954 pubmed publisher
Uhl J, Gujarathi S, Waheed A, Gordon A, Freed E, Gousset K. Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes. J Cell Commun Signal. 2019;13:209-224 pubmed publisher
Robinson McCarthy L, McCarthy K, Raaben M, Piccinotti S, Nieuwenhuis J, Stubbs S, et al. Reconstruction of the cell entry pathway of an extinct virus. PLoS Pathog. 2018;14:e1007123 pubmed publisher
Tokuo H, Bhawan J, Coluccio L. Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis. Sci Rep. 2018;8:10449 pubmed publisher
Santhana Kumar K, Neve A, Guerreiro Stucklin A, Kuzan Fischer C, Rushing E, Taylor M, et al. TGF-? Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma. Cell Rep. 2018;23:3798-3812.e8 pubmed publisher
Wang X, Li J, Xu X, Zheng J, Li Q. miR-129 inhibits tumor growth and potentiates chemosensitivity of neuroblastoma by targeting MYO10. Biomed Pharmacother. 2018;103:1312-1318 pubmed publisher
El Hayek S, Yang Q, Abbassi L, FitzHarris G, Clarke H. Mammalian Oocytes Locally Remodel Follicular Architecture to Provide the Foundation for Germline-Soma Communication. Curr Biol. 2018;28:1124-1131.e3 pubmed publisher
Kroon J, Schaefer A, van Rijssel J, Hoogenboezem M, van Alphen F, Hordijk P, et al. Inflammation-Sensitive Myosin-X Functionally Supports Leukocyte Extravasation by Cdc42-Mediated ICAM-1-Rich Endothelial Filopodia Formation. J Immunol. 2018;200:1790-1801 pubmed publisher
Lehtimäki J, Fenix A, Kotila T, Balistreri G, Paavolainen L, Varjosalo M, et al. UNC-45a promotes myosin folding and stress fiber assembly. J Cell Biol. 2017;216:4053-4072 pubmed publisher
Tasca A, Astleford K, Lederman A, Jensen E, Lee B, Gopalakrishnan R, et al. Regulation of Osteoclast Differentiation by Myosin X. Sci Rep. 2017;7:7603 pubmed publisher
Buccitelli C, Salgueiro L, Rowald K, Sotillo R, Mardin B, Korbel J. Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation. Genome Res. 2017;27:501-511 pubmed publisher
Makowska K, Hughes R, White K, Wells C, Peckham M. Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells. Cell Rep. 2015;13:2118-25 pubmed publisher
Caltagarone J, Ma S, Sorkin A. Dopamine transporter is enriched in filopodia and induces filopodia formation. Mol Cell Neurosci. 2015;68:120-30 pubmed publisher
Snyder J, Rochelle L, Marion S, Lyerly H, Barak L, Caron M. Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions. J Cell Sci. 2015;128:1230-40 pubmed publisher
product information
Catalog Number :
HPA024223
Product Name :
Anti-MYO10 antibody produced in rabbit
Product Type :
ANTIBODIES - SIAL
Product Group :
Protein & Pathway Technologies
Host Species :
rabbit
Clonality :
polyclonal
Conjugation :
unconjugated
Product Description :
Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA