product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-CD8 antibody produced in mouse
catalog :
C7423
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UCHT-4
reactivity :
African green monkey, human
application :
western blot, ELISA, immunocytochemistry, flow cytometry, blocking or activating experiments
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig s1h
Matsumoto A, Pasut A, Matsumoto M, Yamashita R, Fung J, Monteleone E, et al. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide. Nature. 2017;541:228-232 pubmed publisher
  • immunocytochemistry; human; fig s5a
  • western blot; human; fig s5b
Kadlecova Z, Spielman S, Loerke D, Mohanakrishnan A, Reed D, Schmid S. Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2. J Cell Biol. 2017;216:167-179 pubmed publisher
  • blocking or activating experiments; human; loading ...
Elkin S, Oswald N, Reed D, Mettlen M, Macmillan J, Schmid S. Ikarugamycin: A Natural Product Inhibitor of Clathrin-Mediated Endocytosis. Traffic. 2016;17:1139-49 pubmed publisher
  • ELISA; human; fig s5f
Pal K, Hwang S, Somatilaka B, Badgandi H, Jackson P, DeFea K, et al. Smoothened determines ?-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. J Cell Biol. 2016;212:861-75 pubmed publisher
  • immunocytochemistry; human; fig 2
Dieckmann N, Hackmann Y, Aricò M, Griffiths G. Munc18-2 is required for Syntaxin 11 Localization on the Plasma Membrane in Cytotoxic T-Lymphocytes. Traffic. 2015;16:1330-41 pubmed publisher
  • flow cytometry; African green monkey
  • immunocytochemistry; African green monkey; 1:50
Kilisch M, Lytovchenko O, Arakel E, Bertinetti D, Schwappach B. A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1. J Cell Sci. 2016;129:831-42 pubmed publisher
  • immunocytochemistry; human; fig 9a
Billcliff P, Noakes C, Mehta Z, Yan G, Mak L, Woscholski R, et al. OCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates. Mol Biol Cell. 2016;27:90-107 pubmed publisher
Randzavola L, Strege K, Juzans M, Asano Y, Stinchcombe J, Gawden Bone C, et al. Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity. J Clin Invest. 2019;129:5600-5614 pubmed publisher
Simonetti B, Danson C, Heesom K, Cullen P. Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR. J Cell Biol. 2017;216:3695-3712 pubmed publisher
Rosa Garrido M, Ceballos L, Alonso Lecue P, Abraira C, Delgado M, Gandarillas A. A cell cycle role for the epigenetic factor CTCF-L/BORIS. PLoS ONE. 2012;7:e39371 pubmed publisher
Dieli F, Poccia F, Lipp M, Sireci G, Caccamo N, Di Sano C, et al. Differentiation of effector/memory Vdelta2 T cells and migratory routes in lymph nodes or inflammatory sites. J Exp Med. 2003;198:391-7 pubmed
product information
Product No. :
C7423
Product Name :
Monoclonal Anti-CD8 antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
UCHT-4
Applications/Description :
Suitable for flow cytometry: 5 μL using 1 × 10 6 cells
Species Reactivity :
human
Isotype :
IgG2a
Storage :
Store at 2-8°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA