Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; 1:100; loading ...; fig 1b
| Strazic Geljic I, Kucan Brlic P, Angulo G, Brizic I, Lisnić B, Jenus T, et al. Cytomegalovirus protein m154 perturbs the adaptor protein-1 compartment mediating broad-spectrum immune evasion. elife. 2020;9: pubmed publisher
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- immunocytochemistry; chicken; 1:500; fig 4b
| Wang J, Ba G, Han Y, Ming S, Wang M, Fu P, et al. Cyclic GMP-AMP synthase is essential for cytosolic double-stranded DNA and fowl adenovirus serotype 4 triggered innate immune responses in chickens. Int J Biol Macromol. 2020;146:497-507 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig ev1c
| Ehinger Y, Bruyère J, Panayotis N, Abada Y, Borloz E, Matagne V, et al. Huntingtin phosphorylation governs BDNF homeostasis and improves the phenotype of Mecp2 knockout mice. EMBO Mol Med. 2020;12:e10889 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 4c
| Gao G, Zhu C, Liu E, Nabi I. Reticulon and CLIMP-63 regulate nanodomain organization of peripheral ER tubules. PLoS Biol. 2019;17:e3000355 pubmed publisher
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- western blot; rat; loading ...; fig 2b
| Sophie B, Jacob H, Jordan V, Yungki P, Laura F, Yannick P. YAP and TAZ Regulate Cc2d1b and Purβ in Schwann Cells. Front Mol Neurosci. 2019;12:177 pubmed publisher
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- western blot; human; 1:5000; loading ...; fig 1g
| Zeitler B, Froelich S, Marlen K, Shivak D, Yu Q, Li D, et al. Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease. Nat Med. 2019;25:1131-1142 pubmed publisher
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- immunohistochemistry; mouse; 1:200; loading ...; fig 1f
| Le Vasseur M, Chen V, Huang K, Vogl W, Naus C. Pannexin 2 Localizes at ER-Mitochondria Contact Sites. Cancers (Basel). 2019;11: pubmed publisher
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- western blot; mouse; fig 3a
| Su L, Zhou L, Chen F, Wang H, Qian H, Sheng Y, et al. Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites. EMBO J. 2019;38: pubmed publisher
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- western blot; mouse; 1:2000; loading ...; fig 4c
| Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, et al. Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin. EMBO J. 2019;38: pubmed publisher
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- western blot; mouse; fig 7e
| Xu D, Li Y, Wu L, Li Y, Zhao D, Yu J, et al. Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions. J Cell Biol. 2018;217:975-995 pubmed publisher
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- western blot; human; loading ...; fig 4b
| Sasaki Y, Hidaka T, Ueno T, Akiba Takagi M, Oliva Trejo J, Seki T, et al. Sorting Nexin 9 facilitates podocin endocytosis in the injured podocyte. Sci Rep. 2017;7:43921 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:600; loading ...; fig 2e
- immunohistochemistry - frozen section; rat; 1:600; loading ...; fig 6c
| Athanasiou D, Aguilà M, Opefi C, South K, Bellingham J, Bevilacqua D, et al. Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration. Hum Mol Genet. 2017;26:305-319 pubmed publisher
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- western blot; human; loading ...; fig 4d
| Li C, Luo X, Zhao S, Siu G, Liang Y, Chan H, et al. COPI-TRAPPII activates Rab18 and regulates its lipid droplet association. EMBO J. 2017;36:441-457 pubmed publisher
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- western blot; mouse; 1:1000; fig 3
| Liu S, Hossinger A, Hofmann J, Denner P, Vorberg I. Horizontal Transmission of Cytosolic Sup35 Prions by Extracellular Vesicles. MBio. 2016;7: pubmed publisher
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- immunocytochemistry; human; fig 2
| Siu G, Zhou F, Yu M, Zhang L, Wang T, Liang Y, et al. Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation. Sci Rep. 2016;6:23464 pubmed publisher
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- immunohistochemistry - frozen section; mouse; fig s1
- western blot; mouse; fig 4
| Sharoar M, Shi Q, Ge Y, He W, Hu X, Perry G, et al. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016;21:1263-71 pubmed publisher
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- western blot; pigs ; fig 3
| Du J, Ge X, Liu Y, Jiang P, Wang Z, Zhang R, et al. Targeting Swine Leukocyte Antigen Class I Molecules for Proteasomal Degradation by the nsp1α Replicase Protein of the Chinese Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Strain JXwn06. J Virol. 2016;90:682-93 pubmed publisher
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| Radulescu C, Garcia Miralles M, Sidik H, Bardile C, Yusof N, Lee H, et al. Reprint of: Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease. Neurobiol Dis. 2020;135:104744 pubmed publisher
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| Tao S, Tao R, Busch D, Widera M, Schaal H, Drexler I. Sequestration of Late Antigens Within Viral Factories Impairs MVA Vector-Induced Protective Memory CTL Responses. Front Immunol. 2019;10:2850 pubmed publisher
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| Gillet L, Guichard S, Essers M, Rougier J, Abriel H. Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter. Sci Rep. 2019;9:19422 pubmed publisher
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| Gupta S, Biswas J, Gupta P, Singh A, Tiwari S, Mishra A, et al. Salubrinal attenuates nitric oxide mediated PERK:IRE1α: ATF-6 signaling and DNA damage in neuronal cells. Neurochem Int. 2019;131:104581 pubmed publisher
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| Moriyama M, Koshiba T, Ichinohe T. Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses. Nat Commun. 2019;10:4624 pubmed publisher
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| Kosior N, Petkau T, Connolly C, Lu G, Leavitt B. Isolating cells from adult murine brain for validation of cell-type specific cre-mediated deletion. J Neurosci Methods. 2019;328:108422 pubmed publisher
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| Zhu W, Li J, Zhang R, Cai Y, Wang C, Qi S, et al. TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity. EMBO J. 2019;:e102075 pubmed publisher
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| Villalon E, Kline R, Smith C, Lorson Z, Osman E, O Day S, et al. AAV9-Stathmin1 gene delivery improves disease phenotype in an intermediate mouse model of spinal muscular atrophy. Hum Mol Genet. 2019;28:3742-3754 pubmed publisher
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| Düchler M, Czernek L, Peczek L, Cypryk W, Sztiller Sikorska M, Czyz M. Melanoma-Derived Extracellular Vesicles Bear the Potential for the Induction of Antigen-Specific Tolerance. Cells. 2019;8: pubmed publisher
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| Cheng L, Baboo S, Lindsay C, Brusman L, Martinez Bartolome S, Tapia O, et al. Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells. Nucleus. 2019;10:126-143 pubmed publisher
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| Hayashishita M, Kawahara H, Yokota N. BAG6 deficiency induces mis-distribution of mitochondrial clusters under depolarization. FEBS Open Bio. 2019;9:1281-1291 pubmed publisher
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| Birkl D, Quirós M, García Hernández V, Zhou D, Brazil J, Hilgarth R, et al. TNFα promotes mucosal wound repair through enhanced platelet activating factor receptor signaling in the epithelium. Mucosal Immunol. 2019;: pubmed publisher
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| Hasegawa H. Simultaneous induction of distinct protein phase separation events in multiple subcellular compartments of a single cell. Exp Cell Res. 2019;379:92-109 pubmed publisher
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| Ooi J, Langley S, Xu X, Utami K, Sim B, Huang Y, et al. Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects. Cell Rep. 2019;26:2494-2508.e7 pubmed publisher
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| Radulescu C, Garcia Miralles M, Sidik H, Bardile C, Yusof N, Lee H, et al. Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease. Neurobiol Dis. 2019;127:65-75 pubmed publisher
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| Woeste M, Stern S, Raju D, Grahn E, Dittmann D, Gutbrod K, et al. Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations. J Biol Chem. 2019;294:3853-3871 pubmed publisher
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| Murayama T, Ogawa H, Kurebayashi N, Ohno S, Horie M, Sakurai T. A tryptophan residue in the caffeine-binding site of the ryanodine receptor regulates Ca2+ sensitivity. Commun Biol. 2018;1:98 pubmed publisher
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| Pujia A, Russo C, Maurotti S, Pujia R, Mollace V, Romeo S, et al. Bergamot Polyphenol Fraction Exerts Effects on Bone Biology by Activating ERK 1/2 and Wnt/β-Catenin Pathway and Regulating Bone Biomarkers in Bone Cell Cultures. Nutrients. 2018;10: pubmed publisher
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| Arii J, Watanabe M, Maeda F, Tokai Nishizumi N, Chihara T, Miura M, et al. ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity. Nat Commun. 2018;9:3379 pubmed publisher
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| Tanton H, Voronina S, Evans A, Armstrong J, Sutton R, Criddle D, et al. F1F0-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation. Front Physiol. 2018;9:833 pubmed publisher
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| Sachdev R, Kappes Horn K, Paulsen L, Duernberger Y, Pleschka C, Denner P, et al. Endoplasmic Reticulum Stress Induces Myostatin High Molecular Weight Aggregates and Impairs Mature Myostatin Secretion. Mol Neurobiol. 2018;55:8355-8373 pubmed publisher
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| Ehrnhoefer D, Martin D, Schmidt M, Qiu X, Ladha S, Caron N, et al. Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease. Acta Neuropathol Commun. 2018;6:16 pubmed publisher
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| Festa B, Chen Z, Berquez M, Debaix H, Tokonami N, Prange J, et al. Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney. Nat Commun. 2018;9:161 pubmed publisher
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| Poitelon Y, Matafora V, Silvestri N, Zambroni D, McGarry C, Serghany N, et al. A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies. J Neurochem. 2018;145:245-257 pubmed publisher
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| Liu Y, Guo X, Hirata T, Rong Y, Motooka D, Kitajima T, et al. N-Glycan-dependent protein folding and endoplasmic reticulum retention regulate GPI-anchor processing. J Cell Biol. 2018;217:585-599 pubmed publisher
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| Guescini M, Maggio S, Ceccaroli P, Battistelli M, Annibalini G, Piccoli G, et al. Extracellular Vesicles Released by Oxidatively Injured or Intact C2C12 Myotubes Promote Distinct Responses Converging toward Myogenesis. Int J Mol Sci. 2017;18: pubmed publisher
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| Wang T, Wang B, Huang H, Zhang C, Zhu Y, Pei B, et al. Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication. PLoS Pathog. 2017;13:e1006674 pubmed publisher
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| Morabito G, Giannelli S, Ordazzo G, Bido S, Castoldi V, Indrigo M, et al. AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy. Mol Ther. 2017;25:2727-2742 pubmed publisher
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| Gouveia Z, Carlos A, Yuan X, Aires da Silva F, Stocker R, Maghzal G, et al. Characterization of plasma labile heme in hemolytic conditions. FEBS J. 2017;284:3278-3301 pubmed publisher
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| Lirussi D, Ebensen T, Schulze K, Trittel S, Durán V, Liebich I, et al. Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway. EBioMedicine. 2017;22:100-111 pubmed publisher
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| Shi Q, Ge Y, He W, Hu X, Yan R. RTN1 and RTN3 protein are differentially associated with senile plaques in Alzheimer's brains. Sci Rep. 2017;7:6145 pubmed publisher
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| Della Flora Nunes G, Mueller L, Silvestri N, Patel M, Wrabetz L, Feltri M, et al. Acetyl-CoA production from pyruvate is not necessary for preservation of myelin. Glia. 2017;65:1626-1639 pubmed publisher
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| Ghidinelli M, Poitelon Y, Shin Y, Ameroso D, Williamson C, Ferri C, et al. Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination. PLoS Biol. 2017;15:e2001408 pubmed publisher
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| Chan B, Gonçalves Magalhães V, Lemmermann N, Juranic Lisnic V, Stempel M, Bussey K, et al. The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription. PLoS Pathog. 2017;13:e1006382 pubmed publisher
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| Gan W, Zhang C, Siu K, Satoh A, Tanner J, Yu S. ULK1 phosphorylates Sec23A and mediates autophagy-induced inhibition of ER-to-Golgi traffic. BMC Cell Biol. 2017;18:22 pubmed publisher
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| Gursoy Yuzugullu O, Carman C, Serafim R, Myronakis M, Valente V, Price B. Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity. Oncotarget. 2017;8:24518-24532 pubmed publisher
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| Pène V, Lemasson M, Harper F, Pierron G, Rosenberg A. Role of cleavage at the core-E1 junction of hepatitis C virus polyprotein in viral morphogenesis. PLoS ONE. 2017;12:e0175810 pubmed publisher
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| Schaeffer C, Merella S, Pasqualetto E, Lazarevic D, Rampoldi L. Mutant uromodulin expression leads to altered homeostasis of the endoplasmic reticulum and activates the unfolded protein response. PLoS ONE. 2017;12:e0175970 pubmed publisher
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| Salinas R, Pearring J, Ding J, Spencer W, Hao Y, Arshavsky V. Photoreceptor discs form through peripherin-dependent suppression of ciliary ectosome release. J Cell Biol. 2017;216:1489-1499 pubmed publisher
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| Hasegawa H, Hsu A, Tinberg C, Siegler K, Nazarian A, Tsai M. Single amino acid substitution in LC-CDR1 induces Russell body phenotype that attenuates cellular protein synthesis through eIF2? phosphorylation and thereby downregulates IgG secretion despite operational secretory pathway traffic. MAbs. 2017;9:854-873 pubmed publisher
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| Gelmetti V, De Rosa P, Torosantucci L, Marini E, Romagnoli A, Di Rienzo M, et al. PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation. Autophagy. 2017;13:654-669 pubmed publisher
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| Maeda F, Arii J, Hirohata Y, Maruzuru Y, Koyanagi N, Kato A, et al. Herpes Simplex Virus 1 UL34 Protein Regulates the Global Architecture of the Endoplasmic Reticulum in Infected Cells. J Virol. 2017;91: pubmed publisher
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| Uehara A, Murayama T, Yasukochi M, Fill M, Horie M, Okamoto T, et al. Extensive Ca2+ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca2+ hypersensitivity. J Gen Physiol. 2017;149:199-218 pubmed publisher
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| Yan Y, He Y, Boson B, Wang X, Cosset F, Zhong J. A Point Mutation in the N-Terminal Amphipathic Helix α0 in NS3 Promotes Hepatitis C Virus Assembly by Altering Core Localization to the Endoplasmic Reticulum and Facilitating Virus Budding. J Virol. 2017;91: pubmed publisher
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| Chin S, Yang D, Miles A, Eckford P, Molinski S, Wallace B, et al. Attenuation of Phosphorylation-dependent Activation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by Disease-causing Mutations at the Transmission Interface. J Biol Chem. 2017;292:1988-1999 pubmed publisher
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| Rubio A, Luoni M, Giannelli S, Radice I, Iannielli A, Cancellieri C, et al. Rapid and efficient CRISPR/Cas9 gene inactivation in human neurons during human pluripotent stem cell differentiation and direct reprogramming. Sci Rep. 2016;6:37540 pubmed publisher
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| Bolino A, Piguet F, Alberizzi V, Pellegatta M, Rivellini C, Guerrero Valero M, et al. Niacin-mediated Tace activation ameliorates CMT neuropathies with focal hypermyelination. EMBO Mol Med. 2016;8:1438-1454 pubmed publisher
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| Pingitore P, Dongiovanni P, Motta B, Meroni M, Lepore S, Mancina R, et al. PNPLA3 overexpression results in reduction of proteins predisposing to fibrosis. Hum Mol Genet. 2016;25:5212-5222 pubmed publisher
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| Zhang W, Vreeland A, Noy N. RNA-binding protein HuR regulates nuclear import of protein. J Cell Sci. 2016;129:4025-4033 pubmed
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| Poitelon Y, Lopez Anido C, Catignas K, Berti C, Palmisano M, Williamson C, et al. YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells. Nat Neurosci. 2016;19:879-87 pubmed publisher
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| Weber J, Ortiz Rios M, Riess O, Clemens L, Nguyen H. The calpain-suppressing effects of olesoxime in Huntington's disease. Rare Dis. 2016;4:e1153778 pubmed publisher
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| Garofalo T, Matarrese P, Manganelli V, Marconi M, Tinari A, Gambardella L, et al. Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation. Autophagy. 2016;12:917-35 pubmed publisher
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| Pereira M, Martynhak B, Andreatini R, Svenningsson P. 5-HT6 receptor agonism facilitates emotional learning. Front Pharmacol. 2015;6:200 pubmed publisher
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| Poitelon Y, Bogni S, Matafora V, Della Flora Nunes G, Hurley E, Ghidinelli M, et al. Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination. Nat Commun. 2015;6:8303 pubmed publisher
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| Domi T, Porrello E, Velardo D, Capotondo A, Biffi A, Tonlorenzi R, et al. Mesoangioblast delivery of miniagrin ameliorates murine model of merosin-deficient congenital muscular dystrophy type 1A. Skelet Muscle. 2015;5:30 pubmed publisher
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| Xu D, Wang Z, Zhang Y, Jiang W, Pan Y, Song B, et al. PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus. Nat Commun. 2015;6:8100 pubmed publisher
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| Murayama T, Kurebayashi N, Yamazawa T, Oyamada H, Suzuki J, Kanemaru K, et al. Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region. PLoS ONE. 2015;10:e0130606 pubmed publisher
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| Wang Y, Lian Q, Yang B, Yan S, Zhou H, He L, et al. TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING. PLoS Pathog. 2015;11:e1005012 pubmed publisher
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| Milkereit R, Persaud A, Vanoaica L, Guetg A, Verrey F, Rotin D. LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation. Nat Commun. 2015;6:7250 pubmed publisher
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| Raju D, Schonauer S, Hamzeh H, FLYNN K, Bradke F, Vom Dorp K, et al. Accumulation of glucosylceramide in the absence of the beta-glucosidase GBA2 alters cytoskeletal dynamics. PLoS Genet. 2015;11:e1005063 pubmed publisher
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| Michiels C, Fransen P, De Munck D, De Meyer G, Martinet W. Defective autophagy in vascular smooth muscle cells alters contractility and Ca²⺠homeostasis in mice. Am J Physiol Heart Circ Physiol. 2015;308:H557-67 pubmed publisher
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| Torkko J, Primo M, Dirkx R, Friedrich A, Viehrig A, Vergari E, et al. Stability of proICA512/IA-2 and its targeting to insulin secretory granules require β4-sheet-mediated dimerization of its ectodomain in the endoplasmic reticulum. Mol Cell Biol. 2015;35:914-27 pubmed publisher
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| Ooi J, Hayden M, Pouladi M. Inhibition of Excessive Monoamine Oxidase A/B Activity Protects Against Stress-induced Neuronal Death in Huntington Disease. Mol Neurobiol. 2015;52:1850-1861 pubmed publisher
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