This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Benzamil hydrochloride hydrate
catalog :
B2417
citations: 14
Reference
Komarynets O, Chassot A, Bernabeu E, Czogalla J, Roth I, Liaudet N, et al. Aldosterone controls primary cilium length and cell size in renal collecting duct principal cells. FASEB J. 2020;34:2625-2640 pubmed publisher
Jia Y, Zhao Y, Kusakizako T, Wang Y, Pan C, Zhang Y, et al. TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels. Neuron. 2020;105:310-321.e3 pubmed publisher
Ng R, Salem S, Wu S, Wu M, Lin H, Shepherd A, et al. Amplification of Drosophila Olfactory Responses by a DEG/ENaC Channel. Neuron. 2019;104:947-959.e5 pubmed publisher
Mann S, Heide J, Knott T, Airini R, Epureanu F, Deftu A, et al. Recording of multiple ion current components and action potentials in human induced pluripotent stem cell-derived cardiomyocytes via automated patch-clamp. J Pharmacol Toxicol Methods. 2019;:106599 pubmed publisher
Tsujimura T, Ueha R, Yoshihara M, Takei E, Nagoya K, Shiraishi N, et al. Involvement of the epithelial sodium channel in initiation of mechanically evoked swallows in anaesthetized rats. J Physiol. 2019;597:2949-2963 pubmed publisher
Sachs N, Papaspyropoulos A, Zomer van Ommen D, Heo I, Böttinger L, Klay D, et al. Long-term expanding human airway organoids for disease modeling. EMBO J. 2019;38: pubmed publisher
Ydegaard R, Andersen H, Oxlund C, Jacobsen I, Hansen P, Jürgensen J, et al. The acute blood pressure-lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice. Acta Physiol (Oxf). 2019;225:e13189 pubmed publisher
Ballesteros A, Fenollar Ferrer C, Swartz K. Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins. elife. 2018;7: pubmed publisher
Vélez Ortega A, Freeman M, Indzhykulian A, Grossheim J, Frolenkov G. Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells. elife. 2017;6: pubmed publisher
Tosoni K, Cassidy D, Kerr B, Land S, Mehta A. Using Drugs to Probe the Variability of Trans-Epithelial Airway Resistance. PLoS ONE. 2016;11:e0149550 pubmed publisher
Mattes C, Laube M, Thome U. Rapid elevation of sodium transport through insulin is mediated by AKT in alveolar cells. Physiol Rep. 2014;2:e00269 pubmed publisher
Yamazaki M, Kim K, Marcus D. Sodium selectivity of Reissner's membrane epithelial cells. BMC Physiol. 2011;11:4 pubmed publisher
Pierce G, Cole W, Liu K, Massaeli H, Maddaford T, Chen Y, et al. Modulation of cardiac performance by amiloride and several selected derivatives of amiloride. J Pharmacol Exp Ther. 1993;265:1280-91 pubmed
Lane J, McBride D, Hamill O. Structure-activity relations of amiloride and its analogues in blocking the mechanosensitive channel in Xenopus oocytes. Br J Pharmacol. 1992;106:283-6 pubmed
product information
Catalog Number :
B2417
Product Name :
Benzamil hydrochloride hydrate
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA