Hung C, Lombardo P, Malik N, Brun S, Hellberg K, Van Nostrand J, et al. AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy. Sci Adv. 2021;7: pubmed publisher

Iwama H, Mehanna S, Imasaka M, Hashidume S, Nishiura H, Yamamura K, et al. Cathepsin B and D deficiency in the mouse pancreas induces impaired autophagy and chronic pancreatitis. Sci Rep. 2021;11:6596 pubmed publisher

Shin H, Kim H, Oh S, Lee J, Kee M, Ko H, et al. AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy. Nature. 2016;534:553-7 pubmed publisher

Park J, Jung C, Seo M, Otto N, Grunwald D, Kim K, et al. The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14. Autophagy. 2016;12:547-64 pubmed publisher

Toyama E, Herzig S, Courchet J, Lewis T, Losón O, Hellberg K, et al. Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress. Science. 2016;351:275-281 pubmed publisher

Puente C, Hendrickson R, Jiang X. Nutrient-regulated Phosphorylation of ATG13 Inhibits Starvation-induced Autophagy. J Biol Chem. 2016;291:6026-35 pubmed publisher

Kaizuka T, Mizushima N. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol Cell Biol. 2016;36:585-95 pubmed publisher

Park J, Lee D, Kim D. Redefining the role of AMPK in autophagy and the energy stress response. Nat Commun. 2023;14:2994 pubmed publisher

Jacobs K, André Grégoire G, Maghe C, Thys A, Li Y, Harford Wright E, et al. Paracaspase MALT1 regulates glioma cell survival by controlling endo-lysosome homeostasis. EMBO J. 2020;39:e102030 pubmed publisher

Wang L, Xu X, Jiang C, Ma G, Huang Y, Zhang H, et al. mTORC1-PGC1 axis regulates mitochondrial remodeling during reprogramming. FEBS J. 2020;287:108-121 pubmed publisher

Nagata M, Arakawa S, Yamaguchi H, Torii S, Endo H, Tsujioka M, et al. Dram1 regulates DNA damage-induced alternative autophagy. Cell Stress. 2018;2:55-65 pubmed publisher

Lee D, Ahn J, Jang Y, Ha T, Jung C. Oleic acid-induced defective autolysosome shows impaired lipid degradation. Biochem Biophys Res Commun. 2019;513:553-559 pubmed publisher

Wang B, Maxwell B, Joo J, Gwon Y, Messing J, Mishra A, et al. ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97. Mol Cell. 2019;74:742-757.e8 pubmed publisher

Zong Y, Zhang C, Li M, Wang W, Wang Z, Hawley S, et al. Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress. Cell Res. 2019;29:460-473 pubmed publisher

Park J, Lee D, Lee Y, Oh E, Bae K, Oh K, et al. Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity. Autophagy. 2019;:1-20 pubmed publisher

Guha P, Tyagi R, Chowdhury S, Reilly L, Fu C, Xu R, et al. IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration. Cell Rep. 2019;26:2692-2703.e7 pubmed publisher

Kumar S, Gu Y, Abudu Y, Bruun J, Jain A, Farzam F, et al. Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation. Dev Cell. 2019;: pubmed publisher

Pyo K, Kim C, Lee M, Kim J, Kim K, Baek S. ULK1 O-GlcNAcylation Is Crucial for Activating VPS34 via ATG14L during Autophagy Initiation. Cell Rep. 2018;25:2878-2890.e4 pubmed publisher

Fu Y, Hong L, Xu J, Zhong G, Gu Q, Gu Q, et al. Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo. Autophagy. 2018;:1-17 pubmed publisher

Back M, Ha H, Fu Z, Choi J, Piao Y, Won J, et al. Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide. Cell Death Dis. 2018;9:670 pubmed publisher

Zhao Y, Liu N, Miao G, Chen Y, Zhao H, Zhang H. The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis. Curr Biol. 2018;28:1234-1245.e4 pubmed publisher

Chen J, Zhang L, Zhou H, Wang W, Luo Y, Yang H, et al. Inhibition of autophagy promotes cisplatin-induced apoptotic cell death through Atg5 and Beclin 1 in A549 human lung cancer cells. Mol Med Rep. 2018;17:6859-6865 pubmed publisher

Sulli G, Rommel A, Wang X, Kolar M, Puca F, Saghatelian A, et al. Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence. Nature. 2018;553:351-355 pubmed publisher

Li W, Yang Y, Ba Z, Li S, Chen H, Hou X, et al. MicroRNA-93 Regulates Hypoxia-Induced Autophagy by Targeting ULK1. Oxid Med Cell Longev. 2017;2017:2709053 pubmed publisher

Wang B, Iyengar R, Li Harms X, Joo J, Wright C, Lavado A, et al. The Autophagy-Inducing Kinases, ULK1 and ULK2, Regulate Axon Guidance in the Developing Mouse Forebrain via a Noncanonical Pathway. Autophagy. 2017;: pubmed publisher

Laker R, Drake J, Wilson R, Lira V, Lewellen B, Ryall K, et al. Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy. Nat Commun. 2017;8:548 pubmed publisher

McGinnis G, Tang Y, Brewer R, Brahma M, Stanley H, Shanmugam G, et al. Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart. J Mol Cell Cardiol. 2017;110:80-95 pubmed publisher

Liu P, Liu K, Gu H, Wang W, Gong J, Zhu Y, et al. High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1. Cell Death Differ. 2017;24:1672-1680 pubmed publisher

Nishimura T, Tamura N, Kono N, Shimanaka Y, Arai H, Yamamoto H, et al. Autophagosome formation is initiated at phosphatidylinositol synthase-enriched ER subdomains. EMBO J. 2017;36:1719-1735 pubmed publisher

Goldberg A, Nkengfac B, Sanchez A, Moroz N, Qureshi S, Koromilas A, et al. Regulation of ULK1 Expression and Autophagy by STAT1. J Biol Chem. 2017;292:1899-1909 pubmed publisher

Wold M, Lim J, Lachance V, Deng Z, Yue Z. ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models. Mol Neurodegener. 2016;11:76 pubmed

Watanabe Y, Honda S, Konishi A, Arakawa S, Murohashi M, Yamaguchi H, et al. Autophagy controls centrosome number by degrading Cep63. Nat Commun. 2016;7:13508 pubmed publisher

Chen J, David J, Cook Spaeth D, Casey S, Cohen D, Selvendiran K, et al. Autophagy Induction Results in Enhanced Anoikis Resistance in Models of Peritoneal Disease. Mol Cancer Res. 2017;15:26-34 pubmed publisher

Cao Q, Liu F, Yang Z, Fu X, Yang Z, Liu Q, et al. Prognostic value of autophagy related proteins ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12, LC3B and p62/SQSTM1 in gastric cancer. Am J Transl Res. 2016;8:3831-3847 pubmed

Qi X, Man S, Malireddi R, Karki R, Lupfer C, Gurung P, et al. Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection. J Exp Med. 2016;213:2081-97 pubmed publisher

Kim M, Bae S, Ryu J, Kwon Y, Oh J, Kwon J, et al. SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages. Autophagy. 2016;12:1272-91 pubmed publisher

Gammoh N, Fraser J, Puente C, Syred H, Kang H, Ozawa T, et al. Suppression of autophagy impedes glioblastoma development and induces senescence. Autophagy. 2016;12:1431-9 pubmed publisher

Fritzen A, Madsen A, Kleinert M, Treebak J, Lundsgaard A, Jensen T, et al. Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation. J Physiol. 2016;594:745-61 pubmed publisher

Wong P, Feng Y, Wang J, Shi R, Jiang X. Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. Nat Commun. 2015;6:8048 pubmed publisher

Hieke N, Löffler A, Kaizuka T, Berleth N, Böhler P, Drießen S, et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy. 2015;11:1471-83 pubmed publisher

Munson M, Allen G, Toth R, Campbell D, Lucocq J, Ganley I. mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J. 2015;34:2272-90 pubmed publisher

Joshi A, Iyengar R, Joo J, Li Harms X, Wright C, Marino R, et al. Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1. Cell Death Differ. 2016;23:216-30 pubmed publisher

Egan D, Chun M, Vamos M, Zou H, Rong J, Miller C, et al. Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates. Mol Cell. 2015;59:285-97 pubmed publisher

Dey S, Sayers C, Verginadis I, Lehman S, Cheng Y, Cerniglia G, et al. ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis. J Clin Invest. 2015;125:2592-608 pubmed publisher

Tian W, Li W, Chen Y, Yan Z, Huang X, Zhuang H, et al. Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy. FEBS Lett. 2015;589:1847-54 pubmed publisher

Jiao H, Su G, Dong W, Zhang L, Xie W, Yao L, et al. Chaperone-like protein p32 regulates ULK1 stability and autophagy. Cell Death Differ. 2015;22:1812-23 pubmed publisher

Rosenberg L, Lafitte M, Grant W, Chen W, Cleveland J, Duckett D. Development of an HTS-Compatible Assay for the Discovery of Ulk1 Inhibitors. J Biomol Screen. 2015;20:913-20 pubmed publisher

Sharifi M, Mowers E, Drake L, Macleod K. Measuring autophagy in stressed cells. Methods Mol Biol. 2015;1292:129-50 pubmed publisher

Strohecker A, Joshi S, Possemato R, Abraham R, Sabatini D, White E. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening. Oncogene. 2015;34:5662-76 pubmed publisher

Lim J, Lachenmayer M, Wu S, Liu W, Kundu M, Wang R, et al. Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates. PLoS Genet. 2015;11:e1004987 pubmed publisher

Medina D, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, et al. Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB. Nat Cell Biol. 2015;17:288-99 pubmed

Jensen T, Ross F, Kleinert M, Sylow L, Knudsen J, Gowans G, et al. PT-1 selectively activates AMPK-?1 complexes in mouse skeletal muscle, but activates all three ? subunit complexes in cultured human cells by inhibiting the respiratory chain. Biochem J. 2015;467:461-72 pubmed publisher