Published Application/Species/Sample/Dilution | Reference |
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- western blot knockout validation; mouse; 1:1000; loading ...; fig s10f
| Valussi M, Besser J, Wystub Lis K, Zukunft S, Richter M, Kubin T, et al. Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart. Sci Adv. 2021;7:eabi6648 pubmed publisher
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- western blot; rat; loading ...; fig 2b
- western blot; mouse; loading ...; fig 5e
| Huang H, Liu Q, Zhang T, Zhang J, Zhou J, Jing X, et al. Farnesylthiosalicylic Acid-Loaded Albumin Nanoparticle Alleviates Renal Fibrosis by Inhibiting Ras/Raf1/p38 Signaling Pathway. Int J Nanomedicine. 2021;16:6441-6453 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 6c
| Srivastava S, Zhou H, Setia O, Dardik A, Fernandez Hernando C, GOODWIN J. Podocyte Glucocorticoid Receptors Are Essential for Glomerular Endothelial Cell Homeostasis in Diabetes Mellitus. J Am Heart Assoc. 2021;10:e019437 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 1a
- immunocytochemistry; human; 1:1000; loading ...; fig 7b
| Zehender A, Li Y, Lin N, Stefanica A, Nüchel J, Chen C, et al. TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy. Nat Commun. 2021;12:4404 pubmed publisher
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- immunocytochemistry; human; 1:100; loading ...; fig s1g
| Yoo J, Lee D, Park S, Shin H, Lee K, Kim D, et al. Trophoblast glycoprotein is a marker for efficient sorting of ventral mesencephalic dopaminergic precursors derived from human pluripotent stem cells. NPJ Parkinsons Dis. 2021;7:61 pubmed publisher
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- western blot; rat; 1:1000; loading ...; fig 2
| Zhang Y, Hu M, Yang F, Zhang Y, Ma S, Zhang D, et al. Increased uterine androgen receptor protein abundance results in implantation and mitochondrial defects in pregnant rats with hyperandrogenism and insulin resistance. J Mol Med (Berl). 2021;99:1427-1446 pubmed publisher
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- western blot; human; 1:2000; loading ...; fig s1b
| Nam J, Kim A, Choi S, Kim J, Choi K, Cho S, et al. An antibody against L1 cell adhesion molecule inhibits cardiotoxicity by regulating persistent DNA damage. Nat Commun. 2021;12:3279 pubmed publisher
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- immunocytochemistry; human; 1:1000; fig 7b
| Palau V, Nugraha B, Benito D, Pascual J, Emmert M, Hoerstrup S, et al. Both Specific Endothelial and Proximal Tubular Adam17 Deletion Protect against Diabetic Nephropathy. Int J Mol Sci. 2021;22: pubmed publisher
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- immunocytochemistry; human; 1:200; loading ...; fig 1d
| Seol B, Kim Y, Cho Y. Modeling Sialidosis with Neural Precursor Cells Derived from Patient-Derived Induced Pluripotent Stem Cells. Int J Mol Sci. 2021;22: pubmed publisher
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- immunohistochemistry; mouse; loading ...; fig 4c
| Srivastava S, Zhou H, Setia O, Liu B, Kanasaki K, Koya D, et al. Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy. Nat Commun. 2021;12:2368 pubmed publisher
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- immunocytochemistry; human; 1:500; loading ...; fig 5e
| Hemanthakumar K, Fang S, Anisimov A, Mäyränpää M, Mervaala E, Kivela R. Cardiovascular disease risk factors induce mesenchymal features and senescence in mouse cardiac endothelial cells. elife. 2021;10: pubmed publisher
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| Yamamoto A, Morioki H, Nakae T, Miyake Y, Harada T, Noda S, et al. Transcription factor old astrocyte specifically induced substance is a novel regulator of kidney fibrosis. FASEB J. 2021;35:e21158 pubmed publisher
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- western blot; human; 1:5000; loading ...; fig 3h
| Liu Y, Li L, Liu X, Wang Y, Liu L, Peng L, et al. Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling. elife. 2020;9: pubmed publisher
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- immunohistochemistry; human; 1:200; loading ...; fig 1b
| Bennett R, Hu M, Fernandes A, Pérez Rando M, Robbins A, Kamath T, et al. Tau reduction in aged mice does not impact Microangiopathy. Acta Neuropathol Commun. 2020;8:137 pubmed publisher
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- immunocytochemistry; human; 1:50; loading ...; fig 2c
| Pseftogas A, Xanthopoulos K, Poutahidis T, Ainali C, Dafou D, Panteris E, et al. The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGF Signaling. Cancers (Basel). 2020;12: pubmed publisher
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- immunocytochemistry; human; loading ...; fig s1d
| Hu H, Ji Q, Song M, Ren J, Liu Z, Wang Z, et al. ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin. Nucleic Acids Res. 2020;48:6001-6018 pubmed publisher
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- western blot; human; 1:24,000; loading ...; fig 1b
| Bozic M, Caus M, Rodrigues Díez R, Pedraza N, Ruiz Ortega M, Garí E, et al. Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis. Nat Commun. 2020;11:1943 pubmed publisher
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- immunocytochemistry; rat; loading ...; fig s10
- western blot; rat; loading ...; fig 7a
| Guo X, Kolpakov M, Hooshdaran B, Schappell W, Wang T, Eguchi S, et al. Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload. JACC Basic Transl Sci. 2020;5:69-83 pubmed publisher
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- immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 5b
- immunocytochemistry; human; 1:200; loading ...; fig 2a
| Li L, Du Z, Rong B, Zhao D, Wang A, Xu Y, et al. Foam cells promote atherosclerosis progression by releasing CXCL12. Biosci Rep. 2020;40: pubmed publisher
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- immunocytochemistry; human; loading ...; fig 1b, 1c
- western blot; human; fig s3a
| Vijayaraj P, Minasyan A, Durra A, Karumbayaram S, Mehrabi M, Aros C, et al. Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule. Cell Rep. 2019;29:3488-3505.e9 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 5b
| Welk V, Meul T, Lukas C, Kammerl I, Mulay S, Schamberger A, et al. Proteasome activator PA200 regulates myofibroblast differentiation. Sci Rep. 2019;9:15224 pubmed publisher
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- immunohistochemistry - frozen section; chicken; 1:500; loading ...; fig 2a
| Tang W, Martik M, Li Y, Bronner M. Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish. elife. 2019;8: pubmed publisher
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- immunohistochemistry - paraffin section; mouse; loading ...; fig s8c
- western blot; mouse; 1:1000; loading ...; fig 7d
- immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 8a
- western blot; human; 1:500; loading ...; fig 4d
| Rubio K, Singh I, Dobersch S, Sarvari P, Günther S, Cordero J, et al. Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis. Nat Commun. 2019;10:2229 pubmed publisher
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- western blot; human; loading ...; fig 6h
| Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed publisher
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- western blot; human; loading ...; fig s1b
| Niu F, Liao K, Hu G, Sil S, Callen S, Guo M, et al. Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS. J Cell Biol. 2019;218:700-721 pubmed publisher
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- immunohistochemistry - frozen section; mouse; loading ...; fig 7e
- western blot; mouse; loading ...; fig 1c
- western blot; human; loading ...; fig 1a
| Liu Z, Li C, Kang N, Malhi H, Shah V, Maiers J. Transforming growth factor β (TGFβ) cross-talk with the unfolded protein response is critical for hepatic stellate cell activation. J Biol Chem. 2019;294:3137-3151 pubmed publisher
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- western blot; human; loading ...; fig 1c
| Zhang J, Wang D, Wang L, Wang S, Roden A, Zhao H, et al. Profibrotic effect of IL-17A and elevated IL-17RA in idiopathic pulmonary fibrosis and rheumatoid arthritis-associated lung disease support a direct role for IL-17A/IL-17RA in human fibrotic interstitial lung disease. Am J Physiol Lung Cell Mol Physiol. 2019;316:L487-L497 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4a
- western blot; human; 1:1000; loading ...; fig 1b
| He S, Nian F, Chen W, Yin L, Auchoybur M, Tao Z, et al. I-κB kinase-ε knockout protects against angiotensin II induced aortic valve thickening in apolipoprotein E deficient mice. Biomed Pharmacother. 2019;109:1287-1295 pubmed publisher
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- immunocytochemistry; mouse; 1:200; loading ...; fig 3c
| Kim A, Lee E, Lee E, Kim J, Suk K, Lee E, et al. SIRT2 is required for efficient reprogramming of mouse embryonic fibroblasts toward pluripotency. Cell Death Dis. 2018;9:893 pubmed publisher
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- immunocytochemistry; human; 1:500; loading ...; fig 1b
| Karow M, Camp J, Falk S, Gerber T, Pataskar A, Gac Santel M, et al. Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program. Nat Neurosci. 2018;21:932-940 pubmed publisher
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- western blot; mouse; fig 1i
| Zhu F, Zhu Q, Ye D, Zhang Q, Yang Y, Guo X, et al. Sin3a-Tet1 interaction activates gene transcription and is required for embryonic stem cell pluripotency. Nucleic Acids Res. 2018;46:6026-6040 pubmed publisher
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- immunohistochemistry - frozen section; mouse; loading ...; fig 1e
| Wen G, An W, Chen J, Maguire E, Chen Q, Yang F, et al. Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis. J Am Heart Assoc. 2018;7: pubmed publisher
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- western blot; human; loading ...; fig s4b
| Niell N, Larriba M, Ferrer Mayorga G, Sanchez Perez I, Cantero R, Real F, et al. The human PKP2/plakophilin-2 gene is induced by Wnt/?-catenin in normal and colon cancer-associated fibroblasts. Int J Cancer. 2018;142:792-804 pubmed publisher
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- immunocytochemistry; human; 1:400; fig 1j
| Alonso Barroso E, Brasil S, Briso Montiano Á, Navarrete R, Perez Cerda C, Ugarte M, et al. Generation and characterization of a human iPSC line from a patient with propionic acidemia due to defects in the PCCA gene. Stem Cell Res. 2017;23:173-177 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:250; fig 1i
| Bohnenpoll T, Wittern A, Mamo T, Weiss A, Rudat C, Kleppa M, et al. A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017;13:e1006951 pubmed publisher
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- immunohistochemistry; mouse; 1:250; loading ...; fig 5
| Mamo T, Wittern A, Kleppa M, Bohnenpoll T, Weiss A, Kispert A. BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017;26:3553-3563 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3b
- western blot; mouse; 1:500; loading ...; fig 3a
| Cho H, Kim J, Jang H, Lee T, Jung M, Kim T, et al. Alpha-lipoic acid ameliorates the epithelial mesenchymal transition induced by unilateral ureteral obstruction in mice. Sci Rep. 2017;7:46065 pubmed publisher
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- immunocytochemistry; human; fig 3b
- western blot; human; fig 3c
| Al Maqtari T, Hong K, Vajravelu B, Moktar A, Cao P, Moore J, et al. Transcription factor-induced activation of cardiac gene expression in human c-kit+ cardiac progenitor cells. PLoS ONE. 2017;12:e0174242 pubmed publisher
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- immunohistochemistry; mouse; loading ...; fig 4b
| Li N, Xue W, Yuan H, Dong B, Ding Y, Liu Y, et al. AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis. J Clin Invest. 2017;127:1284-1302 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; loading ...; fig 5q
| Dahan J, Levillayer F, Xia T, Nouet Y, Werts C, Fanton d Andon M, et al. LIM-Only Protein FHL2 Is a Negative Regulator of Transforming Growth Factor ?1 Expression. Mol Cell Biol. 2017;37: pubmed publisher
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- western blot; human; 1:1000; fig 1e
| Xu W, Li B, Guan X, Chung S, Wang Y, Yip Y, et al. Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression. Nat Commun. 2017;8:14399 pubmed publisher
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- immunohistochemistry; mouse; 1:200; loading ...; fig s1
| Lim E, Nakanishi S, Hoghooghi V, Eaton S, Palmer A, Frederick A, et al. AlphaB-crystallin regulates remyelination after peripheral nerve injury. Proc Natl Acad Sci U S A. 2017;114:E1707-E1716 pubmed publisher
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- immunohistochemistry - frozen section; human; 1:200; loading ...; fig 6b
| Wu J, Platero Luengo A, Sakurai M, Sugawara A, Gil M, Yamauchi T, et al. Interspecies Chimerism with Mammalian Pluripotent Stem Cells. Cell. 2017;168:473-486.e15 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5d
| Tang J, Shen D, Caranasos T, Wang Z, Vandergriff A, Allen T, et al. Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome. Nat Commun. 2017;8:13724 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:4000; fig 4
| Hesler R, Huang J, Starr M, Treboschi V, Bernanke A, Nixon A, et al. TGF-?-induced stromal CYR61 promotes resistance to gemcitabine in pancreatic ductal adenocarcinoma through downregulation of the nucleoside transporters hENT1 and hCNT3. Carcinogenesis. 2016;37:1041-1051 pubmed publisher
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- immunohistochemistry - paraffin section; human; fig 7
- western blot; human; fig 4
| Masola V, Zaza G, Gambaro G, Onisto M, Bellin G, Vischini G, et al. Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury. PLoS ONE. 2016;11:e0160074 pubmed publisher
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- immunocytochemistry; mouse; 1:200; fig 2c
| Thomsen M, Birkelund S, Burkhart A, Stensballe A, Moos T. Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier. J Neurochem. 2017;140:741-754 pubmed publisher
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- immunocytochemistry; mouse; loading ...; fig 2d
| Lopez R, Byrne S, Vukcevic M, Sekulic Jablanovic M, Xu L, Brink M, et al. An RYR1 mutation associated with malignant hyperthermia is also associated with bleeding abnormalities. Sci Signal. 2016;9:ra68 pubmed publisher
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- immunohistochemistry - paraffin section; rat; 1:100; fig 3
| Zaglia T, Di Bona A, Chioato T, Basso C, Ausoni S, Mongillo M. Optimized protocol for immunostaining of experimental GFP-expressing and human hearts. Histochem Cell Biol. 2016;146:407-19 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 3b
- western blot; human; loading ...; fig 3a
| Zheng X, Xu M, Yao B, Wang C, Jia Y, Liu Q. IL-6/STAT3 axis initiated CAFs via up-regulating TIMP-1 which was attenuated by acetylation of STAT3 induced by PCAF in HCC microenvironment. Cell Signal. 2016;28:1314-24 pubmed publisher
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- immunohistochemistry; human; 1:250; loading ...; fig s9d
| Hyslop L, Blakeley P, Craven L, Richardson J, Fogarty N, Fragouli E, et al. Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease. Nature. 2016;534:383-6 pubmed publisher
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- western blot; rat; 1:1000; fig 1
| Puchert M, Adams V, Linke A, Engele J. Evidence for the involvement of the CXCL12 system in the adaptation of skeletal muscles to physical exercise. Cell Signal. 2016;28:1205-15 pubmed publisher
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- immunocytochemistry; human; 4 ug/ml; loading ...; fig 8
- western blot; human; loading ...; fig 7a
| Kelly J, Esseltine J, Shao Q, Jabs E, SAMPSON J, Auranen M, et al. Specific functional pathologies of Cx43 mutations associated with oculodentodigital dysplasia. Mol Biol Cell. 2016;27:2172-85 pubmed publisher
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- immunocytochemistry; human; 1:400; fig 3
| Son M, Lee M, Jeon H, Seol B, Kim J, Chang J, et al. Generation and characterization of integration-free induced pluripotent stem cells from patients with autoimmune disease. Exp Mol Med. 2016;48:e232 pubmed publisher
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- western blot; human; fig 3B
| Kwon O, Kim K, Lee E, Kim M, Choi S, Li H, et al. Induction of MiR-21 by Stereotactic Body Radiotherapy Contributes to the Pulmonary Fibrotic Response. PLoS ONE. 2016;11:e0154942 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig s6d
- immunocytochemistry; mouse; 1:1000; loading ...; fig 1g
| Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, et al. Tumour resistance in induced pluripotent stem cells derived from naked mole-rats. Nat Commun. 2016;7:11471 pubmed publisher
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- immunocytochemistry; human; 1:1000; loading ...; fig 1d
| Choudhary P, Gutteridge A, Impey E, Storer R, Owen R, Whiting P, et al. Targeting the cAMP and Transforming Growth Factor-? Pathway Increases Proliferation to Promote Re-Epithelialization of Human Stem Cell-Derived Retinal Pigment Epithelium. Stem Cells Transl Med. 2016;5:925-37 pubmed publisher
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- immunohistochemistry - frozen section; human; 1:1000; fig 3
| Krawiec J, Weinbaum J, Liao H, Ramaswamy A, Pezzone D, Josowitz A, et al. In Vivo Functional Evaluation of Tissue-Engineered Vascular Grafts Fabricated Using Human Adipose-Derived Stem Cells from High Cardiovascular Risk Populations. Tissue Eng Part A. 2016;22:765-75 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; fig 1
| Wezel A, De Vries M, Maassen J, Kip P, Peters E, Karper J, et al. Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response. Sci Rep. 2016;6:24248 pubmed publisher
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- immunocytochemistry; human; 1:1000; loading ...; fig 1b
- western blot; human; 1:5000; loading ...; fig 1c
| Choi S, Kim M, Lee H, Kim E, Kim C, Lee Y. Effects of NOX1 on fibroblastic changes of endothelial cells in radiation?induced pulmonary fibrosis. Mol Med Rep. 2016;13:4135-42 pubmed publisher
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- western blot; mouse; fig 2
| Ren J, Li J, Liu X, Feng Y, Gui Y, Yang J, et al. Quercetin Inhibits Fibroblast Activation and Kidney Fibrosis Involving the Suppression of Mammalian Target of Rapamycin and β-catenin Signaling. Sci Rep. 2016;6:23968 pubmed publisher
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- western blot; human; fig 1
| Dey A, Mustafi S, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy. 2016;12:659-70 pubmed publisher
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- immunohistochemistry; human; 1:200; fig 3b
| Meng G, Poon A, Liu S, Rancourt D. An Effective and Reliable Xeno-free Cryopreservation Protocol for Single Human Pluripotent Stem Cells. Methods Mol Biol. 2016;1516:47-56 pubmed publisher
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- immunohistochemistry; mouse; fig 8
| Marneros A. Increased VEGF-A promotes multiple distinct aging diseases of the eye through shared pathomechanisms. EMBO Mol Med. 2016;8:208-31 pubmed publisher
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- immunocytochemistry; human; 1:1000; fig s5
| Fattahi F, Steinbeck J, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, et al. Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. Nature. 2016;531:105-9 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; fig 7
| Jean Charles P, Zhang L, Wu J, Han S, Brian L, Freedman N, et al. Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation. J Biol Chem. 2016;291:7450-64 pubmed publisher
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- western blot; human; 1:3000; fig 1
| Gao Y, Zhao Y, Zhang J, Lu Y, Liu X, Geng P, et al. The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1. Sci Rep. 2016;6:19874 pubmed publisher
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- immunohistochemistry; human; 1:500; fig 8a
| Avgustinova A, Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, et al. Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness. Nat Commun. 2016;7:10305 pubmed publisher
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| Smith K, Zhou B, Avdulov S, Benyumov A, Peterson M, Liu Y, et al. Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is blocked by a chemical antagonist of translation factor eIF4E. Sci Rep. 2015;5:18233 pubmed publisher
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- immunocytochemistry; mouse; 1:400
| Mallol A, Piqué L, Santaló J, Ibáñez E. Morphokinetics of cloned mouse embryos treated with epigenetic drugs and blastocyst prediction. Reproduction. 2016;151:203-14 pubmed publisher
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- western blot; human; 1:2000; loading ...; fig 4b
| Leclercq A, Veillat V, Loriot S, Spuul P, Madonna F, Roques X, et al. A Methodology for Concomitant Isolation of Intimal and Adventitial Endothelial Cells from the Human Thoracic Aorta. PLoS ONE. 2015;10:e0143144 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; fig s4
| Dimitrova N, Gocheva V, Bhutkar A, Resnick R, Jong R, Miller K, et al. Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development. Cancer Discov. 2016;6:188-201 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:500; fig 2
| Jung M, Ryu Y, Kang G. Investigation of the origin of stromal and endothelial cells at the desmoplastic interface in xenograft tumor in mice. Pathol Res Pract. 2015;211:925-30 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2g, h
| Sultana N, Zhang L, Yan J, Chen J, Cai W, Razzaque S, et al. Resident c-kit(+) cells in the heart are not cardiac stem cells. Nat Commun. 2015;6:8701 pubmed publisher
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- western blot; human; fig 3
- immunohistochemistry - frozen section; mouse; fig 7
- western blot; mouse; fig 7
- western blot; rat; fig 3
| Yu D, Makkar G, Strickland D, Blanpied T, Stumpo D, Blackshear P, et al. Myristoylated Alanine-Rich Protein Kinase Substrate (MARCKS) Regulates Small GTPase Rac1 and Cdc42 Activity and Is a Critical Mediator of Vascular Smooth Muscle Cell Migration in Intimal Hyperplasia Formation. J Am Heart Assoc. 2015;4:e002255 pubmed publisher
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- western blot; mouse; fig 4B
| Guan S, Sheu M, Wu C, Chiang C, Liu S. ATP synthase subunit-β down-regulation aggravates diabetic nephropathy. Sci Rep. 2015;5:14561 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:400; fig 5
| Stewart M, Bechberger J, Welch I, Naus C, Laird D. Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer. Oncotarget. 2015;6:37185-99 pubmed publisher
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- immunohistochemistry; mouse; 1:100-1:200
| Gamat M, Malinowski R, Parkhurst L, Steinke L, Marker P. Ornithine Decarboxylase Activity Is Required for Prostatic Budding in the Developing Mouse Prostate. PLoS ONE. 2015;10:e0139522 pubmed publisher
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- immunohistochemistry - frozen section; domestic rabbit; loading ...; fig 3d
| Seidel T, Edelmann J, Sachse F. Analyzing Remodeling of Cardiac Tissue: A Comprehensive Approach Based on Confocal Microscopy and 3D Reconstructions. Ann Biomed Eng. 2016;44:1436-1448 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:1000; fig 4a
| Vandersmissen I, Craps S, Depypere M, Coppiello G, van Gastel N, Maes F, et al. Endothelial Msx1 transduces hemodynamic changes into an arteriogenic remodeling response. J Cell Biol. 2015;210:1239-56 pubmed publisher
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- western blot; rat; 1:1000; fig 4
| Yan G, Wang Q, Hu S, Wang D, Qiao Y, Ma G, et al. Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury. Int J Mol Med. 2015;36:1001-11 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 1c
| Manieri N, Mack M, Himmelrich M, Worthley D, Hanson E, Eckmann L, et al. Mucosally transplanted mesenchymal stem cells stimulate intestinal healing by promoting angiogenesis. J Clin Invest. 2015;125:3606-18 pubmed publisher
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- immunohistochemistry; rat
| Thomsen L, Burkhart A, Moos T. A Triple Culture Model of the Blood-Brain Barrier Using Porcine Brain Endothelial cells, Astrocytes and Pericytes. PLoS ONE. 2015;10:e0134765 pubmed publisher
|
- immunohistochemistry - frozen section; mouse; 1:500; fig 2
| Han H, Yan P, Chen L, Luo C, Gao H, Deng Q, et al. Flaxseed Oil Containing α -Linolenic Acid Ester of Plant Sterol Improved Atherosclerosis in ApoE Deficient Mice. Oxid Med Cell Longev. 2015;2015:958217 pubmed publisher
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- western blot; human; 1:200; fig 4
| Kontro H, Cannino G, Rustin P, Dufour E, Kainulainen H. DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells. PLoS ONE. 2015;10:e0131990 pubmed publisher
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- immunohistochemistry; mouse; 1:10000; fig 6
| Regan J, Kannan P, Kemp M, Kramer B, Newnham J, Jobe A, et al. Damage-Associated Molecular Pattern and Fetal Membrane Vascular Injury and Collagen Disorganization in Lipopolysaccharide-Induced Intra-amniotic Inflammation in Fetal Sheep. Reprod Sci. 2016;23:69-80 pubmed publisher
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- immunocytochemistry; human; 1:1000
| Choudhary P, Dodsworth B, Sidders B, Gutteridge A, Michaelides C, Duckworth J, et al. A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells. PLoS ONE. 2015;10:e0130379 pubmed publisher
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- immunocytochemistry; human
| Huang X, Hu Q, Braun G, Pallaoro A, Morales D, ZASADZINSKI J, et al. Light-activated RNA interference in human embryonic stem cells. Biomaterials. 2015;63:70-9 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:200; fig s1
| Ruozi G, Bortolotti F, Falcione A, Dal Ferro M, Ukovich L, Macedo A, et al. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nat Commun. 2015;6:7388 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:500; fig 2
| Louveau A, Smirnov I, Keyes T, Eccles J, Rouhani S, Peske J, et al. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523:337-41 pubmed publisher
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| Song H, Wang H, Wu W, Qi L, Shao L, Wang F, et al. Inhibitory role of reactive oxygen species in the differentiation of multipotent vascular stem cells into vascular smooth muscle cells in rats: a novel aspect of traditional culture of rat aortic smooth muscle cells. Cell Tissue Res. 2015;362:97-113 pubmed publisher
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- immunocytochemistry; rat; fig 2
- western blot; rat; fig 3
- immunohistochemistry - paraffin section; mouse; fig 4
| Li J, Ren J, Liu X, Jiang L, He W, Yuan W, et al. Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis. Kidney Int. 2015;88:515-27 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 2.5 ug/ml; fig 2
| Yamaleyeva L, Pulgar V, Lindsey S, Yamane L, Varagic J, McGee C, et al. Uterine artery dysfunction in pregnant ACE2 knockout mice is associated with placental hypoxia and reduced umbilical blood flow velocity. Am J Physiol Endocrinol Metab. 2015;309:E84-94 pubmed publisher
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- flow cytometry; mouse; fig 1
| Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, et al. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode. J Exp Med. 2015;212:905-25 pubmed publisher
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- immunohistochemistry; mouse; 1:600; fig s4
| Wu J, Okamura D, Li M, Suzuki K, Luo C, Ma L, et al. An alternative pluripotent state confers interspecies chimaeric competency. Nature. 2015;521:316-21 pubmed publisher
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- western blot; rat; 1:1000; fig 1
| Yongping M, Zhang X, Xuewei L, Fan W, Chen J, Zhang H, et al. Astragaloside prevents BDL-induced liver fibrosis through inhibition of notch signaling activation. J Ethnopharmacol. 2015;169:200-9 pubmed publisher
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- immunohistochemistry - paraffin section; pigs ; 1:100; fig 5
| Bastijanic J, Marchant R, Kligman F, Allemang M, Lakin R, Kendrick D, et al. In vivo evaluation of biomimetic fluorosurfactant polymer-coated expanded polytetrafluoroethylene vascular grafts in a porcine carotid artery bypass model. J Vasc Surg. 2016;63:1620-1630.e4 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 3a
| Kim J, Wang S, Hyun J, Choi S, Cha H, Ock M, et al. Hepatic stellate cells express thymosin Beta 4 in chronically damaged liver. PLoS ONE. 2015;10:e0122758 pubmed publisher
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- immunocytochemistry; human; 1:100
| Videla Richardson G, Garcia C, Roisman A, Slavutsky I, Fernandez Espinosa D, Romorini L, et al. Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence. Brain Pathol. 2016;26:43-61 pubmed publisher
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- immunohistochemistry; human; fig 2
| Yoshiba N, Yoshiba K, Ohkura N, Takei E, Edanami N, Oda Y, et al. Correlation between Fibrillin-1 Degradation and mRNA Downregulation and Myofibroblast Differentiation in Cultured Human Dental Pulp Tissue. J Histochem Cytochem. 2015;63:438-48 pubmed publisher
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- immunocytochemistry; human; 1:400; fig 2
- western blot; human; 1:1000; fig 2
| Kim S, Wen W, Prowse P, Hamilton D. Regulation of matrix remodelling phenotype in gingival fibroblasts by substratum topography. J Cell Mol Med. 2015;19:1183-96 pubmed publisher
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- immunohistochemistry; mouse; 1:15000; fig s3
| Kijani S, Yrlid U, Heyden M, Levin M, Borén J, Fogelstrand P. Filter-Dense Multicolor Microscopy. PLoS ONE. 2015;10:e0119499 pubmed publisher
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- immunohistochemistry - paraffin section; rat
| Otsuki S, Sawada H, Yodoya N, Shinohara T, Kato T, Ohashi H, et al. Potential contribution of phenotypically modulated smooth muscle cells and related inflammation in the development of experimental obstructive pulmonary vasculopathy in rats. PLoS ONE. 2015;10:e0118655 pubmed publisher
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- immunohistochemistry - frozen section; human; 1:1000; fig 2
| Coutelle O, Schiffmann L, Liwschitz M, Brunold M, Goede V, Hallek M, et al. Dual targeting of Angiopoetin-2 and VEGF potentiates effective vascular normalisation without inducing empty basement membrane sleeves in xenograft tumours. Br J Cancer. 2015;112:495-503 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:30000
| Vogels R, Vlenterie M, Versleijen Jonkers Y, Ruijter E, Bekers E, Verdijk M, et al. Solitary fibrous tumor - clinicopathologic, immunohistochemical and molecular analysis of 28 cases. Diagn Pathol. 2014;9:224 pubmed publisher
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- immunohistochemistry; mouse; 1:4000
| Heude Ã, Bellessort B, Fontaine A, Hamazaki M, Treier A, Treier M, et al. Etiology of craniofacial malformations in mouse models of blepharophimosis, ptosis and epicanthus inversus syndrome. Hum Mol Genet. 2015;24:1670-81 pubmed publisher
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- immunohistochemistry - frozen section; mouse
| Zhu L, He Z, Wu F, Ding R, Jiang Q, Zhang J, et al. Immunization with advanced glycation end products modified low density lipoprotein inhibits atherosclerosis progression in diabetic apoE and LDLR null mice. Cardiovasc Diabetol. 2014;13:151 pubmed publisher
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- immunohistochemistry; mouse; fig 1
| Taniguchi T, Asano Y, Akamata K, Noda S, Takahashi T, Ichimura Y, et al. Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice. Arthritis Rheumatol. 2015;67:517-26 pubmed publisher
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- immunohistochemistry - paraffin section; mouse
| Venalis P, Kumánovics G, Schulze Koops H, Distler A, Dees C, Zerr P, et al. Cardiomyopathy in murine models of systemic sclerosis. Arthritis Rheumatol. 2015;67:508-16 pubmed publisher
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- immunocytochemistry; mouse; 1:1000; fig 3
| Lim A, Shin K, Zhao C, Kawano S, Beachy P. Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate. Nat Cell Biol. 2014;16:1135-45 pubmed publisher
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- immunocytochemistry; human; 1:400
| Kim W, Barron D, San Martin R, Chan K, Tran L, Yang F, et al. RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation. Proc Natl Acad Sci U S A. 2014;111:16389-94 pubmed publisher
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- western blot; human; fig 1
| Cai X, Dai Z, Reeves R, Caballero Benítez A, Duran K, Delrow J, et al. Autonomous stimulation of cancer cell plasticity by the human NKG2D lymphocyte receptor coexpressed with its ligands on cancer cells. PLoS ONE. 2014;9:e108942 pubmed publisher
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- western blot; human; fig s2
| Gray A, Stephens C, Bigelow R, Coleman D, Cardelli J. The polyphenols (-)-epigallocatechin-3-gallate and luteolin synergistically inhibit TGF-β-induced myofibroblast phenotypes through RhoA and ERK inhibition. PLoS ONE. 2014;9:e109208 pubmed publisher
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- immunohistochemistry - frozen section; human; fig 2
| Calabro S, Maczurek A, Morgan A, Tu T, Wen V, Yee C, et al. Hepatocyte produced matrix metalloproteinases are regulated by CD147 in liver fibrogenesis. PLoS ONE. 2014;9:e90571 pubmed publisher
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- immunocytochemistry; human
| Carlessi L, Fusar Poli E, Bechi G, Mantegazza M, Pascucci B, Narciso L, et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis. 2014;5:e1342 pubmed publisher
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- immunohistochemistry; mouse; fig 5
- western blot; mouse; fig 5
| Ying Y, Kim J, Westphal S, Long K, Padanilam B. Targeted deletion of p53 in the proximal tubule prevents ischemic renal injury. J Am Soc Nephrol. 2014;25:2707-16 pubmed publisher
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- immunocytochemistry; human; 1:250
- immunohistochemistry; human; 1:250
| Balk Møller E, Kim J, Hopkinson B, Timmermans Wielenga V, Petersen O, Villadsen R. A marker of endocrine receptor-positive cells, CEACAM6, is shared by two major classes of breast cancer: luminal and HER2-enriched. Am J Pathol. 2014;184:1198-208 pubmed publisher
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- immunohistochemistry; mouse
| Kaenel P, Hahnewald S, Wotzkow C, Strange R, Andres A. Overexpression of EphB4 in the mammary epithelium shifts the differentiation pathway of progenitor cells and promotes branching activity and vascularization. Dev Growth Differ. 2014;56:255-75 pubmed publisher
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- immunocytochemistry; rat
- western blot; rat
| Kennedy E, Hakimjavadi R, Greene C, Mooney C, Fitzpatrick E, Collins L, et al. Embryonic rat vascular smooth muscle cells revisited - a model for neonatal, neointimal SMC or differentiated vascular stem cells?. Vasc Cell. 2014;6:6 pubmed publisher
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- immunohistochemistry; mouse
| Namba F, Go H, Murphy J, La P, Yang G, Sengupta S, et al. Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model. PLoS ONE. 2014;9:e90936 pubmed publisher
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- reverse phase protein lysate microarray; human; 1:500
| Milara J, Peiró T, Serrano A, Guijarro R, Zaragozá C, Tenor H, et al. Roflumilast N-oxide inhibits bronchial epithelial to mesenchymal transition induced by cigarette smoke in smokers with COPD. Pulm Pharmacol Ther. 2014;28:138-48 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:100
| Hum S, Rymer C, Schaefer C, Bushnell D, Sims Lucas S. Ablation of the renal stroma defines its critical role in nephron progenitor and vasculature patterning. PLoS ONE. 2014;9:e88400 pubmed publisher
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- immunohistochemistry; mouse
| Sastre C, Fernández Laso V, Madrigal Matute J, Munoz Garcia B, Moreno J, Pastor Vargas C, et al. Genetic deletion or TWEAK blocking antibody administration reduce atherosclerosis and enhance plaque stability in mice. J Cell Mol Med. 2014;18:721-34 pubmed publisher
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- immunohistochemistry; mouse
| Yoshida T, Yamashita M, Horimai C, Hayashi M. Deletion of Krüppel-like factor 4 in endothelial and hematopoietic cells enhances neointimal formation following vascular injury. J Am Heart Assoc. 2014;3:e000622 pubmed publisher
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- immunohistochemistry; mouse; fig 1
| Cagnet S, Faraldo M, Kreft M, Sonnenberg A, Raymond K, Glukhova M. Signaling events mediated by ?3?1 integrin are essential for mammary tumorigenesis. Oncogene. 2014;33:4286-95 pubmed publisher
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- immunohistochemistry; mouse; 1:4000
- immunohistochemistry; human; 1:4000
| Burger N, Haak M, de Bakker B, Al Shaibani Z, de Groot C, Christoffels V, et al. Systematic analysis of the development of the ductus venosus in wild type mouse and human embryos. Early Hum Dev. 2013;89:1067-73 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:1000
| Orecchioni S, Gregato G, Martin Padura I, Reggiani F, Braidotti P, Mancuso P, et al. Complementary populations of human adipose CD34+ progenitor cells promote growth, angiogenesis, and metastasis of breast cancer. Cancer Res. 2013;73:5880-91 pubmed publisher
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| Bouacida A, Rosset P, Trichet V, Guilloton F, Espagnolle N, Cordonier T, et al. Pericyte-like progenitors show high immaturity and engraftment potential as compared with mesenchymal stem cells. PLoS ONE. 2012;7:e48648 pubmed publisher
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- western blot; chicken; 1:10000
| Kosla J, Dvorak M, Cermák V. Molecular analysis of the TGF-beta controlled gene expression program in chicken embryo dermal myofibroblasts. Gene. 2013;513:90-100 pubmed publisher
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- immunohistochemistry; mouse; 1:2000; fig 4
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| Sha W, Thompson K, South J, Baron M, Leask A. Loss of PPAR? expression by fibroblasts enhances dermal wound closure. Fibrogenesis Tissue Repair. 2012;5:5 pubmed publisher
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- immunocytochemistry; mouse; fig s2b
| Tondeleir D, Lambrechts A, Muller M, Jonckheere V, Doll T, Vandamme D, et al. Cells lacking ?-actin are genetically reprogrammed and maintain conditional migratory capacity. Mol Cell Proteomics. 2012;11:255-71 pubmed publisher
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- immunohistochemistry; human; 1:5000
| Yamada Y, Yamamoto H, Ohishi Y, Nishiyama K, Fukuhara M, Saitou T, et al. Sclerosing variant of perivascular epithelioid cell tumor in the female genital organs. Pathol Int. 2011;61:768-72 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:600
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| Ho C, Chen Y, Tsai M, Tsai H, Weng C, Yet S, et al. Ambient Particulate Matter Induces Vascular Smooth Muscle Cell Phenotypic Changes via NOX1/ROS/NF-κB Dependent and Independent Pathways: Protective Effects of Polyphenols. Antioxidants (Basel). 2021;10: pubmed publisher
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| Gromisch C, Tan G, Pasion K, Moran A, Gromisch M, Grinstaff M, et al. Humanized anti-DEspR IgG4S228P antibody increases overall survival in a pancreatic cancer stem cell-xenograft peritoneal carcinomatosis ratnu/nu model. BMC Cancer. 2021;21:407 pubmed publisher
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| Liang C, Liu Z, Song M, Li W, Wu Z, Wang Z, et al. Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration. Cell Res. 2021;31:187-205 pubmed publisher
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| Hu J, Kong S, Dong T, Lin Z, Zhang Q, Chen X, et al. Autophagy modulates mesenchymal-to-endothelial transition via p53. Aging (Albany NY). 2020;12:22112-22121 pubmed publisher
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| Liu N, Fu D, Yang J, Liu P, Song X, Wang X, et al. Asiatic acid attenuates hypertrophic and fibrotic differentiation of articular chondrocytes via AMPK/PI3K/AKT signaling pathway. Arthritis Res Ther. 2020;22:112 pubmed publisher
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| Lu Y, Jan Y, Ko B, Liang S, Chen L, Wu C, et al. Expression of Nik-related kinase in smooth muscle cells attenuates vascular inflammation and intimal hyperplasia. Aging (Albany NY). 2020;12:7511-7533 pubmed publisher
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| Marsit O, Clavel M, Côté Laroche C, Hadjadj S, Bouchard M, Handschumacher M, et al. Attenuated Mitral Leaflet Enlargement Contributes to Functional Mitral Regurgitation After Myocardial Infarction. J Am Coll Cardiol. 2020;75:395-405 pubmed publisher
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