This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
5-(N-Ethyl-N-isopropyl)amiloride
catalog :
A3085
citations: 205
Reference
O Hara B, Morris Love J, Gee G, Haley S, Atwood W. JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor. PLoS Pathog. 2020;16:e1008371 pubmed publisher
Michalopoulou E, Auciello F, Bulusu V, Strachan D, Campbell A, Tait Mulder J, et al. Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition. Cell Rep. 2020;30:2729-2742.e4 pubmed publisher
Qin M, Zhang J, Li M, Yang D, Liu D, Song S, et al. Proteomic analysis of intracellular protein corona of nanoparticles elucidates nano-trafficking network and nano-bio interactions. Theranostics. 2020;10:1213-1229 pubmed publisher
Peng H, Purkerson J, Freeman R, Schwaderer A, Schwartz G. Acidosis induces antimicrobial peptide expression and resistance to uropathogenic E. coli infection in kidney collecting duct cells via HIF-1α. Am J Physiol Renal Physiol. 2020;318:F468-F474 pubmed publisher
Doll F, Keckeis P, Scheel P, Cölfen H. Visualizing Cholesterol Uptake by Self-Assembling Rhodamine B-Labeled Polymer Inside Living Cells via FLIM-FRET Microscopy. Macromol Biosci. 2020;20:e1900081 pubmed publisher
Stévenin V, Chang Y, Le Toquin Y, Duchateau M, Gianetto Q, Luk C, et al. Dynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche. Cell Rep. 2019;29:3958-3973.e7 pubmed publisher
Ramírez C, Hauser A, Vucic E, Bar Sagi D. Plasma membrane V-ATPase controls oncogenic RAS-induced macropinocytosis. Nature. 2019;576:477-481 pubmed publisher
Francia V, Yang K, Deville S, Reker Smit C, Nelissen I, Salvati A. Corona Composition Can Affect the Mechanisms Cells Use to Internalize Nanoparticles. ACS Nano. 2019;13:11107-11121 pubmed publisher
Liu X, Ghosh D. Intracellular nanoparticle delivery by oncogenic KRAS-mediated macropinocytosis. Int J Nanomedicine. 2019;14:6589-6600 pubmed publisher
Morad G, Carman C, Hagedorn E, Perlin J, Zon L, Mustafaoglu N, et al. Tumor-Derived Extracellular Vesicles Breach the Intact Blood-Brain Barrier via Transcytosis. ACS Nano. 2019;13:13853-13865 pubmed publisher
Feng J, Wu Y, Zhang L, Li Y, Liu S, Wang H, et al. Enhanced Chemical Stability, Intestinal Absorption, and Intracellular Antioxidant Activity of Cyanidin-3-O-glucoside by Composite Nanogel Encapsulation. J Agric Food Chem. 2019;67:10432-10447 pubmed publisher
Kamei N, Yamamoto S, Hashimoto H, Nishii M, Miyaura M, Tomada K, et al. Optimization of the method for analyzing endocytosis of fluorescently tagged molecules: Impact of incubation in the cell culture medium and cell surface wash with glycine-hydrochloric acid buffer. J Control Release. 2019;310:127-140 pubmed publisher
Tang J, Frascaroli G, Lebbink R, Ostermann E, Brune W. Human cytomegalovirus glycoprotein B variants affect viral entry, cell fusion, and genome stability. Proc Natl Acad Sci U S A. 2019;116:18021-18030 pubmed publisher
Salloum G, Jakubik C, Erami Z, Heitz S, Bresnick A, Backer J. PI3Kβ is selectively required for growth factor-stimulated macropinocytosis. J Cell Sci. 2019;132: pubmed publisher
Lee J, Pasquarella J, Kalejta R. Cell Line Models for Human Cytomegalovirus Latency Faithfully Mimic Viral Entry by Macropinocytosis and Endocytosis. J Virol. 2019;93: pubmed publisher
Palamidessi A, Malinverno C, Frittoli E, Corallino S, Barbieri E, Sigismund S, et al. Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma. Nat Mater. 2019;18:1252-1263 pubmed publisher
Wang H, Chi C, Xu Y, Wang C, Wang T, Lv D, et al. Occludin endocytosis is involved in the disruption of the intestinal epithelial barrier in a mouse model of alcoholic steatohepatitis. J Dig Dis. 2019;20:476-485 pubmed publisher
Kim Y, Zhao K, Thompson D, Liu D. An anionic human protein mediates cationic liposome delivery of genome editing proteins into mammalian cells. Nat Commun. 2019;10:2905 pubmed publisher
Wu M, Guo H, Liu L, Liu Y, Xie L. Size-dependent cellular uptake and localization profiles of silver nanoparticles. Int J Nanomedicine. 2019;14:4247-4259 pubmed publisher
Ghoshal P, Singla B, Lin H, Cherian Shaw M, Tritz R, Padgett C, et al. Loss of GTPase activating protein neurofibromin stimulates paracrine cell communication via macropinocytosis. Redox Biol. 2019;:101224 pubmed publisher
Wang R, Xu X, Hao Z, Zhang S, Wu D, Sun H, et al. Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis. Neurosci Bull. 2019;: pubmed publisher
Lee J, Kalejta R. Human Cytomegalovirus Enters the Primary CD34+ Hematopoietic Progenitor Cells where it Establishes Latency by Macropinocytosis. J Virol. 2019;: pubmed publisher
Zhao H, Xu J, Huang W, Zhan G, Zhao Y, Chen H, et al. Spatiotemporally Light-Activatable Platinum Nanocomplexes for Selective and Cooperative Cancer Therapy. ACS Nano. 2019;13:6647-6661 pubmed publisher
Ichimizu S, Watanabe H, Maeda H, Hamasaki K, Ikegami K, Chuang V, et al. Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape. J Control Release. 2019;304:156-163 pubmed publisher
Gao X, De Mazière A, Iaea D, Arthur C, Klumperman J, Ciferri C, et al. Visualizing the cellular route of entry of a cystine-knot peptide with Xfect transfection reagent by electron microscopy. Sci Rep. 2019;9:6907 pubmed publisher
Tejeda Muñoz N, Albrecht L, Bui M, De Robertis E. Wnt canonical pathway activates macropinocytosis and lysosomal degradation of extracellular proteins. Proc Natl Acad Sci U S A. 2019;116:10402-10411 pubmed publisher
Wiebe S, Plain A, Pan W, O Neill D, Braam B, Alexander R. NHE8 attenuates Ca2+ influx into NRK cells and the proximal tubule epithelium. Am J Physiol Renal Physiol. 2019;317:F240-F253 pubmed publisher
Yang D, Liu D, Deng H, Zhang J, Qin M, Yuan L, et al. Transferrin Functionization Elevates Transcytosis of Nanogranules across Epithelium by Triggering Polarity-Associated Transport Flow and Positive Cellular Feedback Loop. ACS Nano. 2019;13:5058-5076 pubmed publisher
Byun J, Park M, Yun J, Lee J, Kim J, Cho S, et al. Oncogenic KRAS signaling activates mTORC1 through COUP-TFII-mediated lactate production. EMBO Rep. 2019;20: pubmed publisher
Moreau H, Blanch Mercader C, Attia R, Maurin M, Alraies Z, Sanséau D, et al. Macropinocytosis Overcomes Directional Bias in Dendritic Cells Due to Hydraulic Resistance and Facilitates Space Exploration. Dev Cell. 2019;: pubmed publisher
Kosaka T, Goda M, Inoue M, Yakushi T, Yamada M. Flagellum-mediated motility in Pelotomaculum thermopropionicum SI. Biosci Biotechnol Biochem. 2019;83:1362-1371 pubmed publisher
Herrador A, Fedeli C, Radulovic E, Campbell K, Moreno H, Gerold G, et al. Dynamic Dystroglycan Complexes Mediate Cell Entry of Lassa Virus. MBio. 2019;10: pubmed publisher
Colin M, Delporte C, Janky R, Lechon A, Renard G, Van Antwerpen P, et al. Dysregulation of Macropinocytosis Processes in Glioblastomas May Be Exploited to Increase Intracellular Anti-Cancer Drug Levels: The Example of Temozolomide. Cancers (Basel). 2019;11: pubmed publisher
Okuda A, Tahara S, Hirose H, Takeuchi T, Nakase I, Ono A, et al. Oligoarginine-Bearing Tandem Repeat Penetration-Accelerating Sequence Delivers Protein to Cytosol via Caveolae-Mediated Endocytosis. Biomacromolecules. 2019;20:1849-1859 pubmed publisher
Torriani G, Mayor J, Zimmer G, Kunz S, Rothenberger S, Engler O. Macropinocytosis contributes to hantavirus entry into human airway epithelial cells. Virology. 2019;531:57-68 pubmed publisher
Stevens L, Moffat K, Cooke L, Nomikou K, Mertens P, Jackson T, et al. A low-passage insect-cell isolate of bluetongue virus uses a macropinocytosis-like entry pathway to infect natural target cells derived from the bovine host. J Gen Virol. 2019;100:568-582 pubmed publisher
Stewart C, Dorion S, Ottenbrite M, LeBlond N, Smith T, Qiu S, et al. A Diacylglycerol Kinase Inhibitor, R-59-022, Blocks Filovirus Internalization in Host Cells. Viruses. 2019;11: pubmed publisher
Smith W, Johnston D, Holmes S, Wensley H, Flavell S, Flavell D. Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents. Toxins (Basel). 2019;11: pubmed publisher
Kim N, Kim S, Nahm M, Kopke D, Kim J, Cho E, et al. BMP-dependent synaptic development requires Abi-Abl-Rac signaling of BMP receptor macropinocytosis. Nat Commun. 2019;10:684 pubmed publisher
Thu P, Zheng Z, Zhou Y, Wang Y, Zhang X, Jing D, et al. Phellodendrine chloride suppresses proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis. Eur J Pharmacol. 2019;850:23-34 pubmed publisher
Zhao T, Cui L, Yu X, Zhang Z, Shen X, Hua X. Porcine sapelovirus enters PK-15 cells via caveolae-dependent endocytosis and requires Rab7 and Rab11. Virology. 2019;529:160-168 pubmed publisher
Kwok H, Ning Z, Chong P, Wan T, Ng M, Ho G, et al. Transfer of Extracellular Vesicle-Associated-RNAs Induces Drug Resistance in ALK-Translocated Lung Adenocarcinoma. Cancers (Basel). 2019;11: pubmed publisher
Liu H, Sun M, Liu Z, Kong C, Kong W, Ye J, et al. KRAS-enhanced macropinocytosis and reduced FcRn-mediated recycling sensitize pancreatic cancer to albumin-conjugated drugs. J Control Release. 2019;296:40-53 pubmed publisher
Li Z, Mbah N, Overmeyer J, Sarver J, George S, Trabbic C, et al. The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma. BMC Cancer. 2019;19:77 pubmed publisher
Kluge M, Namkoong E, Khakipoor S, Park K, Roussa E. Differential regulation of vacuolar H+ -ATPase subunits by transforming growth factor-β1 in salivary ducts. J Cell Physiol. 2019;: pubmed publisher
Becker M, Dominguez M, Greune L, Soria Martinez L, Pfleiderer M, Schowalter R, et al. Infectious Entry of Merkel Cell Polyomavirus. J Virol. 2019;93: pubmed publisher
Torriani G, Trofimenko E, Mayor J, Fedeli C, Moreno H, Michel S, et al. Identification of Clotrimazole Derivatives as Specific Inhibitors of Arenavirus Fusion. J Virol. 2019;93: pubmed publisher
Jensen H, Pedersen G, Morgen J, Parsons M, Pedersen S, Nejsum L. The Na+ /H+ exchanger NHE1 localizes as clusters to cryptic lamellipodia and accelerates collective epithelial cell migration. J Physiol. 2019;597:849-867 pubmed publisher
Knudsen J, Hamilton A, Ramracheya R, Tarasov A, Brereton M, Haythorne E, et al. Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production. Cell Metab. 2019;29:430-442.e4 pubmed publisher
González Domínguez I, Grimaldi N, Cervera L, Ventosa N, Godia F. Impact of physicochemical properties of DNA/PEI complexes on transient transfection of mammalian cells. N Biotechnol. 2019;49:88-97 pubmed publisher
Shah J, Rouaud F, Guerrera D, Vasileva E, Popov L, Kelley W, et al. A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote α-Toxin Cytotoxicity. Cell Rep. 2018;25:2132-2147.e7 pubmed publisher
Viñas J, Spence M, Gutsol A, Knoll W, Burger D, Zimpelmann J, et al. Receptor-Ligand Interaction Mediates Targeting of Endothelial Colony Forming Cell-derived Exosomes to the Kidney after Ischemic Injury. Sci Rep. 2018;8:16320 pubmed publisher
Sun D, Tasca A, Haas M, Baltazar G, Harland R, Finkbeiner W, et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205:279-292 pubmed publisher
Yao Z, Qiao Y, Li X, Chen J, Ding J, Bai L, et al. Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity. J Virol. 2018;92: pubmed publisher
Liu B, Lee B, Nakanishi K, Villasante A, Williamson R, Metz J, et al. Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells. Nat Biomed Eng. 2018;2:293-303 pubmed publisher
Filippakis H, Belaid A, Siroky B, Wu C, Alesi N, Hougard T, et al. Vps34-mediated macropinocytosis in Tuberous Sclerosis Complex 2-deficient cells supports tumorigenesis. Sci Rep. 2018;8:14161 pubmed publisher
Takashina Y, Manabe A, Hasegawa H, Matsunaga T, Endo S, Ikari A. Sodium Citrate Increases Expression and Flux of Mg2+ Transport Carriers Mediated by Activation of MEK/ERK/c-Fos Pathway in Renal Tubular Epithelial Cells. Nutrients. 2018;10: pubmed publisher
Liu W, Zhang L, Xuan K, Hu C, Liu S, Liao L, et al. Alpl prevents bone ageing sensitivity by specifically regulating senescence and differentiation in mesenchymal stem cells. Bone Res. 2018;6:27 pubmed publisher
Hardison R, Heimlich D, Harrison A, Beatty W, Rains S, Moseley M, et al. Transient Nutrient Deprivation Promotes Macropinocytosis-Dependent Intracellular Bacterial Community Development. mSphere. 2018;3: pubmed publisher
Wang W, Suga T, Hagimori M, Kuroda N, Fuchigami Y, Kawakami S. Investigation of Intracellular Delivery of NuBCP-9 by Conjugation with Oligoarginines Peptides in MDA-MB-231 Cells. Biol Pharm Bull. 2018;41:1448-1455 pubmed publisher
Canfarotta F, Czulak J, Guerreiro A, Cruz A, Piletsky S, Bergdahl G, et al. A novel capacitive sensor based on molecularly imprinted nanoparticles as recognition elements. Biosens Bioelectron. 2018;120:108-114 pubmed publisher
Lopez Charcas O, Espinosa A, Alfaro A, Herrera Carrillo Z, Ramírez Cordero B, Cortes Reynosa P, et al. The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity. Sci Rep. 2018;8:12995 pubmed publisher
Subramanian B, Moissoglu K, Parent C. The LTB4-BLT1 axis regulates the polarized trafficking of chemoattractant GPCRs during neutrophil chemotaxis. J Cell Sci. 2018;131: pubmed publisher
Peretti M, Raciti F, Carlini V, Verduci I, Sertic S, Barozzi S, et al. Mutual Influence of ROS, pH, and CLIC1 Membrane Protein in the Regulation of G1-S Phase Progression in Human Glioblastoma Stem Cells. Mol Cancer Ther. 2018;17:2451-2461 pubmed publisher
Song S, Fu H, He B, Wang D, Qin M, Yang D, et al. Rho GTPases in A549 and Caco-2 cells dominating the endocytic pathways of nanocarbons with different morphologies. Int J Nanomedicine. 2018;13:4391-4404 pubmed publisher
Shorthouse D, Riedel A, Kerr E, Pedro L, Bihary D, Samarajiwa S, et al. Exploring the role of stromal osmoregulation in cancer and disease using executable modelling. Nat Commun. 2018;9:3011 pubmed publisher
Mishra R, Haldar S, PLACENCIO V, Madhav A, Rohena Rivera K, Agarwal P, et al. Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming. J Clin Invest. 2018;128:4472-4484 pubmed publisher
Ji X, Wang C, Tang M, Guo D, Peng F, Zhong Y, et al. Biocompatible protamine sulfate@silicon nanoparticle-based gene nanocarriers featuring strong and stable fluorescence. Nanoscale. 2018;10:14455-14463 pubmed publisher
Kawami M, Shimonakamura T, Yumoto R, Takano M. Transport of AOPP-Albumin into Human Alveolar Epithelial A549 Cell. J Pharm Pharm Sci. 2018;21:247-255 pubmed publisher
Szczepanski A, Owczarek K, Milewska A, Baster Z, Rajfur Z, Mitchell J, et al. Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells. Vet Res. 2018;49:55 pubmed publisher
Dey P, Bergmann T, Cuellar Camacho J, Ehrmann S, Chowdhury M, Zhang M, et al. Multivalent Flexible Nanogels Exhibit Broad-Spectrum Antiviral Activity by Blocking Virus Entry. ACS Nano. 2018;12:6429-6442 pubmed publisher
Gao R, Ma J, Wen Z, Yang P, Zhao J, Xue M, et al. Tumor cell-released autophagosomes (TRAP) enhance apoptosis and immunosuppressive functions of neutrophils. Oncoimmunology. 2018;7:e1438108 pubmed publisher
Ahmed S, Okuma K, Matsumura K. Comparative analysis of the cellular entry of polystyrene and gold nanoparticles using the freeze concentration method. Biomater Sci. 2018;6:1791-1799 pubmed publisher
Wang X, Sheng W, Wang Y, Li L, Li Y, Zhang S, et al. A Macropinocytosis-Intensifying Albumin Domain-Based scFv Antibody and Its Conjugate Directed against K-Ras Mutant Pancreatic Cancer. Mol Pharm. 2018;15:2403-2412 pubmed publisher
Ford C, NANS A, Boucrot E, Hayward R. Chlamydia exploits filopodial capture and a macropinocytosis-like pathway for host cell entry. PLoS Pathog. 2018;14:e1007051 pubmed publisher
Tsujimoto H, Anderson M, Myles K, Adelman Z. Identification of Candidate Iron Transporters From the ZIP/ZnT Gene Families in the Mosquito Aedes aegypti. Front Physiol. 2018;9:380 pubmed publisher
Alvarez Arguedas S, Uranga S, Martín M, Elizalde J, Gomez A, Julián E, et al. Therapeutic efficacy of the live-attenuated Mycobacterium tuberculosis vaccine, MTBVAC, in a preclinical model of bladder cancer. Transl Res. 2018;197:32-42 pubmed publisher
Bazzani L, Donnini S, Giachetti A, Christofori G, Ziche M. PGE2 mediates EGFR internalization and nuclear translocation via caveolin endocytosis promoting its transcriptional activity and proliferation in human NSCLC cells. Oncotarget. 2018;9:14939-14958 pubmed publisher
Becker M, Greune L, Schmidt M, Schelhaas M. Extracellular Conformational Changes in the Capsid of Human Papillomaviruses Contribute to Asynchronous Uptake into Host Cells. J Virol. 2018;92: pubmed publisher
Ménard L, Floc h N, Martin M, Cross D. Reactivation of Mutant-EGFR Degradation through Clathrin Inhibition Overcomes Resistance to EGFR Tyrosine Kinase Inhibitors. Cancer Res. 2018;78:3267-3279 pubmed publisher
Jaldin Fincati J, Pereira R, Bilan P, Klip A. Insulin uptake and action in microvascular endothelial cells of lymphatic and blood origin. Am J Physiol Endocrinol Metab. 2018;315:E204-E217 pubmed publisher
Yang D, Liu D, Qin M, Chen B, Song S, Dai W, et al. Intestinal Mucin Induces More Endocytosis but Less Transcytosis of Nanoparticles across Enterocytes by Triggering Nanoclustering and Strengthening the Retrograde Pathway. ACS Appl Mater Interfaces. 2018;10:11443-11456 pubmed publisher
Rizzi C, Tiberi A, Giustizieri M, Marrone M, Gobbo F, Carucci N, et al. NGF steers microglia toward a neuroprotective phenotype. Glia. 2018;66:1395-1416 pubmed publisher
Zhang B, Wang X, Li Y, Wu M, Wang S, Li S. Matrine Is Identified as a Novel Macropinocytosis Inducer by a Network Target Approach. Front Pharmacol. 2018;9:10 pubmed publisher
Larabee J, Hauck G, Ballard J. Cell-penetrating peptides derived from Clostridium difficile TcdB2 and a related large clostridial toxin. J Biol Chem. 2018;293:1810-1819 pubmed publisher
Hara H, Kume S, Iizuka T, Fujimoto Y, Kimura A. Enzymatically synthesized megalo-type isomaltosaccharides enhance the barrier function of the tight junction in the intestinal epithelium. Biosci Biotechnol Biochem. 2017;:1-7 pubmed publisher
Patel D, Rorbach J, Downes K, Szukszto M, Pekalski M, Minczuk M. Macropinocytic entry of isolated mitochondria in epidermal growth factor-activated human osteosarcoma cells. Sci Rep. 2017;7:12886 pubmed publisher
Linares J, Cordes T, Duran A, Reina Campos M, Valencia T, Ahn C, et al. ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma. Cell Metab. 2017;26:817-829.e6 pubmed publisher
Dykes S, Steffan J, Cardelli J. Lysosome trafficking is necessary for EGF-driven invasion and is regulated by p38 MAPK and Na+/H+ exchangers. BMC Cancer. 2017;17:672 pubmed publisher
Costa Verdera H, Gitz Francois J, Schiffelers R, Vader P. Cellular uptake of extracellular vesicles is mediated by clathrin-independent endocytosis and macropinocytosis. J Control Release. 2017;266:100-108 pubmed publisher
Seguin L, Camargo M, Wettersten H, Kato S, Desgrosellier J, von Schalscha T, et al. Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers. Cancer Discov. 2017;7:1464-1479 pubmed publisher
Roberts Dalton H, Cocks A, Falcon Perez J, Sayers E, Webber J, Watson P, et al. Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic. Nanoscale. 2017;9:13693-13706 pubmed publisher
Shi H, Zhao X, Ding Z, Han C, Jiang Y, Qian W, et al. Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells. Cell Physiol Biochem. 2017;42:2418-2429 pubmed publisher
Choi J, Kim H, Bae Y, Cheong H. REP1 Modulates Autophagy and Macropinocytosis to Enhance Cancer Cell Survival. Int J Mol Sci. 2017;18: pubmed publisher
Yuan X, Xie Q, Su K, Li Z, Dong D, Wu B. Systemic delivery of the anticancer agent arenobufagin using polymeric nanomicelles. Int J Nanomedicine. 2017;12:4981-4989 pubmed publisher
Kim S, Lee Y, Kim S, Park J, Lee D, Choi J, et al. Covalent, Non-Covalent, Encapsulated Nanodrug Regulate the Fate of Intra- and Extracellular Trafficking: Impact on Cancer and Normal Cells. Sci Rep. 2017;7:6454 pubmed publisher
Saulite L, Dapkute D, Pleiko K, Popena I, Steponkiene S, Rotomskis R, et al. Nano-engineered skin mesenchymal stem cells: potential vehicles for tumour-targeted quantum-dot delivery. Beilstein J Nanotechnol. 2017;8:1218-1230 pubmed publisher
Zhao H, Gulesserian S, Ganesan S, Ou J, Morrison K, Zeng Z, et al. Inhibition of Megakaryocyte Differentiation by Antibody-Drug Conjugates (ADCs) is Mediated by Macropinocytosis: Implications for ADC-induced Thrombocytopenia. Mol Cancer Ther. 2017;16:1877-1886 pubmed publisher
Halamoda Kenzaoui B, Ceridono M, Urbán P, Bogni A, Ponti J, Gioria S, et al. The agglomeration state of nanoparticles can influence the mechanism of their cellular internalisation. J Nanobiotechnology. 2017;15:48 pubmed publisher
Shi Y, Shi Z, Li S, Zhang Y, He B, Peng D, et al. The interactions of single-wall carbon nanohorns with polar epithelium. Int J Nanomedicine. 2017;12:4177-4194 pubmed publisher
Kamerkar S, LeBleu V, Sugimoto H, Yang S, Ruivo C, Melo S, et al. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. 2017;546:498-503 pubmed publisher
Deng W, Xie Q, Wang H, Ma Z, Wu B, Zhang X. Selenium nanoparticles as versatile carriers for oral delivery of insulin: Insight into the synergic antidiabetic effect and mechanism. Nanomedicine. 2017;13:1965-1974 pubmed publisher
Nakase I, Noguchi K, Aoki A, Takatani Nakase T, Fujii I, Futaki S. Arginine-rich cell-penetrating peptide-modified extracellular vesicles for active macropinocytosis induction and efficient intracellular delivery. Sci Rep. 2017;7:1991 pubmed publisher
Kitazawa S, Nishizawa S, Nakagawa H, Funata M, Nishimura K, Soga T, et al. Cancer with low cathepsin D levels is susceptible to vacuolar (H+ )-ATPase inhibition. Cancer Sci. 2017;108:1185-1193 pubmed publisher
Pacitto R, Gaeta I, Swanson J, Yoshida S. CXCL12-induced macropinocytosis modulates two distinct pathways to activate mTORC1 in macrophages. J Leukoc Biol. 2017;101:683-692 pubmed publisher
Wang D, Zhou Y, Li X, Qu X, Deng Y, Wang Z, et al. Mechanisms of pH-Sensitivity and Cellular Internalization of PEOz-b-PLA Micelles with Varied Hydrophilic/Hydrophobic Ratios and Intracellular Trafficking Routes and Fate of the Copolymer. ACS Appl Mater Interfaces. 2017;9:6916-6930 pubmed publisher
Nishida Aoki N, Tominaga N, Takeshita F, Sonoda H, Yoshioka Y, Ochiya T. Disruption of Circulating Extracellular Vesicles as a Novel Therapeutic Strategy against Cancer Metastasis. Mol Ther. 2017;25:181-191 pubmed publisher
Zhu B, Shang B, Du Y, Li Y, Li L, Xu X, et al. A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis. Oncotarget. 2017;8:14748-14758 pubmed publisher
Zimmer A, Wilson J, Wright P, Hiroi J, Wood C. Different mechanisms of Na+ uptake and ammonia excretion by the gill and yolk sac epithelium of early life stage rainbow trout. J Exp Biol. 2017;220:775-786 pubmed publisher
Csanyi G, Feck D, Ghoshal P, Singla B, Lin H, Nagarajan S, et al. CD47 and Nox1 Mediate Dynamic Fluid-Phase Macropinocytosis of Native LDL. Antioxid Redox Signal. 2017;26:886-901 pubmed publisher
Sanchez L, Yi Y, Yu Y. Effect of partial PEGylation on particle uptake by macrophages. Nanoscale. 2017;9:288-297 pubmed publisher
Seo J, Choi J, Lee S, Sung S, Yoo H, Kang M, et al. Autophagy is required for PDAC glutamine metabolism. Sci Rep. 2016;6:37594 pubmed publisher
Juks C, Lorents A, Arukuusk P, Langel U, Pooga M. Cell-penetrating peptides recruit type A scavenger receptors to the plasma membrane for cellular delivery of nucleic acids. FASEB J. 2017;31:975-988 pubmed publisher
Park J, Peng H, Katsnelson J, Yang W, Kaplan N, Dong Y, et al. MicroRNAs-103/107 coordinately regulate macropinocytosis and autophagy. J Cell Biol. 2016;215:667-685 pubmed
Ulmschneider B, Grillo Hill B, Benitez M, Azimova D, Barber D, Nystul T. Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation. J Cell Biol. 2016;215:345-355 pubmed
Park H, Jeon E, Lee J, Hong S, Cho A, Lee J, et al. Galactosylated Lipidoid Nanoparticles for Delivery of Small Interfering RNA to Inhibit Hepatitis C Viral Replication In Vivo. Adv Healthc Mater. 2016;5:2931-2941 pubmed publisher
Nakamura K, Sawada K, Kinose Y, Yoshimura A, Toda A, Nakatsuka E, et al. Exosomes Promote Ovarian Cancer Cell Invasion through Transfer of CD44 to Peritoneal Mesothelial Cells. Mol Cancer Res. 2017;15:78-92 pubmed publisher
Luo Z, Cao X, Li C, Wu M, Yang X, Zhao J, et al. The heparin-binding domain of HB-EGF as an efficient cell-penetrating peptide for drug delivery. J Pept Sci. 2016;22:689-699 pubmed publisher
Pfeiler S, Khandagale A, Magenau A, Nichols M, Heijnen H, Rinninger F, et al. Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI. Sci Rep. 2016;6:34440 pubmed publisher
Basagiannis D, Zografou S, Murphy C, Fotsis T, Morbidelli L, Ziche M, et al. VEGF induces signalling and angiogenesis by directing VEGFR2 internalisation through macropinocytosis. J Cell Sci. 2016;129:4091-4104 pubmed
Kao L, Azimov R, Shao X, Frausto R, Abuladze N, Newman D, et al. Multifunctional ion transport properties of human SLC4A11: comparison of the SLC4A11-B and SLC4A11-C variants. Am J Physiol Cell Physiol. 2016;311:C820-C830 pubmed publisher
Adamo G, Grimaldi N, Sabatino M, Walo M, Dispenza C, Ghersi G. E-beam crosslinked nanogels conjugated with monoclonal antibodies in targeting strategies. Biol Chem. 2017;398:277-287 pubmed publisher
Lee J, Kang M, Mahapatra C, Kim H. Effect of Aminated Mesoporous Bioactive Glass Nanoparticles on the Differentiation of Dental Pulp Stem Cells. PLoS ONE. 2016;11:e0150727 pubmed publisher
He B, Yuan L, Dai W, Gao W, Zhang H, Wang X, et al. Dynamic bio-adhesion of polymer nanoparticles on MDCK epithelial cells and its impact on bio-membranes, endocytosis and paracytosis. Nanoscale. 2016;8:6129-45 pubmed publisher
Han S, Guo H, Sun S, Jin Y, Wei Y, Feng X, et al. Productive Entry of Foot-and-Mouth Disease Virus via Macropinocytosis Independent of Phosphatidylinositol 3-Kinase. Sci Rep. 2016;6:19294 pubmed publisher
Nishioka R, Sugimoto K, Aono H, Mise A, Choudhury M, Miyanishi K, et al. Treadmill exercise ameliorates ischemia-induced brain edema while suppressing Na⁺/H⁺ exchanger 1 expression. Exp Neurol. 2016;277:150-161 pubmed publisher
Song Q, Wang X, Wang Y, Liang Y, Zhou Y, Song X, et al. Reduction Responsive Self-Assembled Nanoparticles Based on Disulfide-Linked Drug-Drug Conjugate with High Drug Loading and Antitumor Efficacy. Mol Pharm. 2016;13:190-201 pubmed publisher
Forte M, Iachetta G, Tussellino M, Carotenuto R, Prisco M, De Falco M, et al. Polystyrene nanoparticles internalization in human gastric adenocarcinoma cells. Toxicol In Vitro. 2016;31:126-36 pubmed publisher
Sung S, Choi J, Cheong H. Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras. Oncotarget. 2015;6:40405-17 pubmed publisher
Zeineddine R, Pundavela J, Corcoran L, Stewart E, Do Ha D, Bax M, et al. SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation. Mol Neurodegener. 2015;10:57 pubmed publisher
Bastien E, Schneider R, Hackbarth S, Dumas D, Jasniewski J, Röder B, et al. PAMAM G4.5-chlorin e6 dendrimeric nanoparticles for enhanced photodynamic effects. Photochem Photobiol Sci. 2015;14:2203-12 pubmed publisher
Zannikou M, Bellou S, Eliades P, Hatzioannou A, Mantzaris M, Carayanniotis G, et al. DNA-histone complexes as ligands amplify cell penetration and nuclear targeting of anti-DNA antibodies via energy-independent mechanisms. Immunology. 2016;147:73-81 pubmed publisher
Gildea J, Xu P, Carlson J, Gaglione R, Bigler Wang D, Kemp B, et al. The sodium-bicarbonate cotransporter NBCe2 (slc4a5) expressed in human renal proximal tubules shows increased apical expression under high-salt conditions. Am J Physiol Regul Integr Comp Physiol. 2015;309:R1447-59 pubmed publisher
Konstantakou E, Voutsinas G, Velentzas A, Basogianni A, Paronis E, Balafas E, et al. 3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants. Mol Cancer. 2015;14:135 pubmed publisher
Lin T, Su Y, Lee K, Chuang C. The J-domain of heat shock protein 40 can enhance the transduction efficiency of arginine-rich cell-penetrating peptides. Biomed Res Int. 2015;2015:698067 pubmed publisher
Johansen L, Dewald L, Shoemaker C, Hoffstrom B, Lear Rooney C, Stossel A, et al. A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity. Sci Transl Med. 2015;7:290ra89 pubmed publisher
Nakase I, Kobayashi N, Takatani Nakase T, Yoshida T. Active macropinocytosis induction by stimulation of epidermal growth factor receptor and oncogenic Ras expression potentiates cellular uptake efficacy of exosomes. Sci Rep. 2015;5:10300 pubmed publisher
Lucas M, Morrison J. An investigation into the relationship between small intestinal fluid secretion and systemic arterial blood pressure in the anesthetized rat. Physiol Rep. 2015;3: pubmed publisher
Bürki S, Gaschen V, Stoffel M, Stojiljkovic A, Frey J, Kuehni Boghenbor K, et al. Invasion and persistence of Mycoplasma bovis in embryonic calf turbinate cells. Vet Res. 2015;46:53 pubmed publisher
Yang L, Carrillo M, Wu Y, DiAngelo S, Silveyra P, Umstead T, et al. SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation. PLoS ONE. 2015;10:e0126576 pubmed publisher
Ip W, Medzhitov R. Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation. Nat Commun. 2015;6:6931 pubmed publisher
Raimondi L, De Luca A, Amodio N, Manno M, Raccosta S, Taverna S, et al. Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation. Oncotarget. 2015;6:13772-89 pubmed
Theparambil S, Deitmer J. High effective cytosolic H+ buffering in mouse cortical astrocytes attributable to fast bicarbonate transport. Glia. 2015;63:1581-94 pubmed publisher
Murai M, Habu S, Murakami S, Ito T, Miyoshi H. Production of new amilorides as potent inhibitors of mitochondrial respiratory complex I. Biosci Biotechnol Biochem. 2015;79:1061-6 pubmed publisher
Wang H, Zhang H, Zhang J, Li Y, Zhao B, Feng G, et al. Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells. Nat Commun. 2015;6:6240 pubmed publisher
Liu B, Huang Y, Aronstam R, Lee H. Comparative mechanisms of protein transduction mediated by cell-penetrating peptides in prokaryotes. J Membr Biol. 2015;248:355-68 pubmed publisher
Manoharan P, Gayam S, Arthur S, Palaniappan B, Singh S, Dick G, et al. Chronic and selective inhibition of basolateral membrane Na-K-ATPase uniquely regulates brush border membrane Na absorption in intestinal epithelial cells. Am J Physiol Cell Physiol. 2015;308:C650-6 pubmed publisher
Wang X, Low X, Hou W, Abdullah L, Toh T, Mohd Abdul Rashid M, et al. Epirubicin-adsorbed nanodiamonds kill chemoresistant hepatic cancer stem cells. ACS Nano. 2014;8:12151-66 pubmed publisher
Kim H, Kim S, Pyun H, Maeng J, Lee K. Cellular uptake mechanism of TCTP-PTD in human lung carcinoma cells. Mol Pharm. 2015;12:194-203 pubmed publisher
Burkard C, Verheije M, Wicht O, van Kasteren S, van Kuppeveld F, Haagmans B, et al. Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner. PLoS Pathog. 2014;10:e1004502 pubmed publisher
Caì Y, Postnikova E, Bernbaum J, Yú S, Mazur S, Deiuliis N, et al. Simian hemorrhagic fever virus cell entry is dependent on CD163 and uses a clathrin-mediated endocytosis-like pathway. J Virol. 2015;89:844-56 pubmed publisher
Lou J, Low Nam S, Kerkvliet J, Hoppe A. Delivery of CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages. J Cell Sci. 2014;127:5228-39 pubmed publisher
Bannunah A, Vllasaliu D, Lord J, Stolnik S. Mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Mol Pharm. 2014;11:4363-73 pubmed publisher
Brasen J, Burford J, McDonough A, Holstein Rathlou N, Peti Peterdi J. Local pH domains regulate NHE3-mediated Na⁺ reabsorption in the renal proximal tubule. Am J Physiol Renal Physiol. 2014;307:F1249-62 pubmed publisher
Fiorentino I, Gualtieri R, Barbato V, Mollo V, Braun S, Angrisani A, et al. Energy independent uptake and release of polystyrene nanoparticles in primary mammalian cell cultures. Exp Cell Res. 2015;330:240-7 pubmed publisher
Wang S, Huang X, Huang Y, Hao X, Xu H, Cai M, et al. Entry of a novel marine DNA virus, Singapore grouper iridovirus, into host cells occurs via clathrin-mediated endocytosis and macropinocytosis in a pH-dependent manner. J Virol. 2014;88:13047-63 pubmed publisher
Freeman M, Peek C, Becker M, Smith E, Denison M. Coronaviruses induce entry-independent, continuous macropinocytosis. MBio. 2014;5:e01340-14 pubmed publisher
Hong N, Garvin J. Endogenous flow-induced superoxide stimulates Na/H exchange activity via PKC in thick ascending limbs. Am J Physiol Renal Physiol. 2014;307:F800-5 pubmed publisher
Bi Y, Mukhopadhyay D, Drinane M, Ji B, Li X, Cao S, et al. Endocytosis of collagen by hepatic stellate cells regulates extracellular matrix dynamics. Am J Physiol Cell Physiol. 2014;307:C622-33 pubmed publisher
Eltoukhy A, Sahay G, Cunningham J, Anderson D. Niemann-Pick C1 affects the gene delivery efficacy of degradable polymeric nanoparticles. ACS Nano. 2014;8:7905-13 pubmed publisher
Qian Y, Wang X, Liu Y, Li Y, Colvin R, Tong L, et al. Extracellular ATP is internalized by macropinocytosis and induces intracellular ATP increase and drug resistance in cancer cells. Cancer Lett. 2014;351:242-51 pubmed publisher
Zhang Y, Whittaker G. Influenza entry pathways in polarized MDCK cells. Biochem Biophys Res Commun. 2014;450:234-9 pubmed publisher
Hashimoto M, Nasser H, Chihara T, Suzu S. Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef. Cell Death Dis. 2014;5:e1267 pubmed publisher
Mattes C, Laube M, Thome U. Rapid elevation of sodium transport through insulin is mediated by AKT in alveolar cells. Physiol Rep. 2014;2:e00269 pubmed publisher
Zürcher C, Sauter K, Mathys V, Wyss F, Schweizer M. Prolonged activity of the pestiviral RNase Erns as an interferon antagonist after uptake by clathrin-mediated endocytosis. J Virol. 2014;88:7235-43 pubmed publisher
Tauber P, Penton D, Stindl J, Humberg E, Tegtmeier I, Sterner C, et al. Pharmacology and pathophysiology of mutated KCNJ5 found in adrenal aldosterone-producing adenomas. Endocrinology. 2014;155:1353-62 pubmed publisher
Guh Y, Tseng Y, Yang C, Hwang P. Endothelin-1 regulates H?-ATPase-dependent transepithelial H? secretion in zebrafish. Endocrinology. 2014;155:1728-37 pubmed publisher
Younger M, Muller M, Tong A, Pym E, Davis G. A presynaptic ENaC channel drives homeostatic plasticity. Neuron. 2013;79:1183-96 pubmed publisher
Perez Carro R, Sanchez Alcudia R, Perez B, Navarrete R, Perez Cerda C, Ugarte M, et al. Functional analysis and in vitro correction of splicing FAH mutations causing tyrosinemia type I. Clin Genet. 2014;86:167-71 pubmed publisher
Ogando D, Jalimarada S, Zhang W, Vithana E, Bonanno J. SLC4A11 is an EIPA-sensitive Na(+) permeable pHi regulator. Am J Physiol Cell Physiol. 2013;305:C716-27 pubmed publisher
Roginiel A, Kohut D, Kaur S, Saleh A, Weber T, Geibel P, et al. Effect of NSAIDs on Na⁺/H⁺ exchanger activity in rat colonic crypts. Am J Physiol Cell Physiol. 2013;305:C512-8 pubmed publisher
Lin Q, Chen J, Ng K, Cao W, Zhang Z, Zheng G. Imaging the cytosolic drug delivery mechanism of HDL-like nanoparticles. Pharm Res. 2014;31:1438-49 pubmed publisher
Redelman Sidi G, Iyer G, Solit D, Glickman M. Oncogenic activation of Pak1-dependent pathway of macropinocytosis determines BCG entry into bladder cancer cells. Cancer Res. 2013;73:1156-67 pubmed publisher
Morishita M, Ariyoshi W, Okinaga T, Usui M, Nakashima K, Nishihara T. A. actinomycetemcomitans LPS enhances foam cell formation induced by LDL. J Dent Res. 2013;92:241-6 pubmed publisher
Emami H, Talab S, Nezami B, Elmi A, Assa S, Ostovaneh M, et al. Na(+)-H+ exchange inhibition attenuates ischemic injury in rat random pattern skin flap: the role of mitochondrial ATP-sensitive potassium channels. Eur J Pharmacol. 2013;698:330-4 pubmed publisher
Wilson J, Moreira Silva J, Delgado I, Ebanks S, Vijayan M, Coimbra J, et al. Mechanisms of transepithelial ammonia excretion and luminal alkalinization in the gut of an intestinal air-breathing fish, Misgurnus anguilliacaudatus. J Exp Biol. 2013;216:623-32 pubmed publisher
Loqman M, Bush P, Farquharson C, Hall A. Suppression of mammalian bone growth by membrane transport inhibitors. J Cell Biochem. 2013;114:658-68 pubmed publisher
Castañeda Corral G, Rocha Gonzalez H, Araiza Saldana C, Vidal Cantú G, Miguel Jiménez Andrade J, Murbartián J, et al. Blockade of peripheral and spinal Na+/H+ exchanger increases formalin-induced long-lasting mechanical allodynia and hyperalgesia in rats. Brain Res. 2012;1475:19-30 pubmed publisher
Iversen T, Frerker N, Sandvig K. Uptake of ricinB-quantum dot nanoparticles by a macropinocytosis-like mechanism. J Nanobiotechnology. 2012;10:33 pubmed publisher
Schewe B, Blenau W, Walz B. Intracellular pH regulation in unstimulated Calliphora salivary glands is Na+ dependent and requires V-ATPase activity. J Exp Biol. 2012;215:1337-45 pubmed publisher
Brix K, Grosell M. Comparative characterization of Na+ transport in Cyprinodon variegatus variegatus and Cyprinodon variegatus hubbsi: a model species complex for studying teleost invasion of freshwater. J Exp Biol. 2012;215:1199-209 pubmed publisher
Serafino A, Moroni N, Psaila R, Zonfrillo M, Andreola F, Wannenes F, et al. Anti-proliferative effect of atrial natriuretic peptide on colorectal cancer cells: evidence for an Akt-mediated cross-talk between NHE-1 activity and Wnt/?-catenin signaling. Biochim Biophys Acta. 2012;1822:1004-18 pubmed publisher
Aureli M, Loberto N, Bassi R, Ferraretto A, Perego S, Lanteri P, et al. Plasma membrane-associated glycohydrolases activation by extracellular acidification due to proton exchangers. Neurochem Res. 2012;37:1296-307 pubmed publisher
Sakuma S, Suita M, Yamamoto T, Masaoka Y, Kataoka M, Yamashita S, et al. Performance of cell-penetrating peptide-linked polymers physically mixed with poorly membrane-permeable molecules on cell membranes. Eur J Pharm Biopharm. 2012;81:64-73 pubmed publisher
Escoffier J, Krapf D, Navarrete F, Darszon A, Visconti P. Flow cytometry analysis reveals a decrease in intracellular sodium during sperm capacitation. J Cell Sci. 2012;125:473-85 pubmed publisher
Lauritzen G, Stock C, Lemaire J, Lund S, Jensen M, Damsgaard B, et al. The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2. Cancer Lett. 2012;317:172-83 pubmed publisher
Lee H, Rho J, Gui S, Kim M, Lee Y, Lee Y, et al. Effect of aldosterone on the amplification of oncolytic vaccinia virus in human cancer lines. Korean J Hepatol. 2011;17:213-9 pubmed publisher
Rahn E, Petermann P, Hsu M, Rixon F, Knebel Mörsdorf D. Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent. PLoS ONE. 2011;6:e25464 pubmed publisher
Aleksandrowicz P, Marzi A, Biedenkopf N, Beimforde N, Becker S, Hoenen T, et al. Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis. J Infect Dis. 2011;204 Suppl 3:S957-67 pubmed publisher
Vargas P, Wangensteen R, Rodríguez Gómez I, Pérez Abud R, Osuna A, Quesada A, et al. Contribution of the amiloride-sensitive component and the Na+/H+ exchanger to renal responsiveness to vasoconstrictors. Pharmacology. 2011;88:142-8 pubmed publisher
Mulherkar N, Raaben M, de la Torre J, Whelan S, Chandran K. The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway. Virology. 2011;419:72-83 pubmed publisher
Nguyen T, Bonanno J. Bicarbonate, NBCe1, NHE, and carbonic anhydrase activity enhance lactate-H+ transport in bovine corneal endothelium. Invest Ophthalmol Vis Sci. 2011;52:8086-93 pubmed publisher
Goh G, Huang H, Ullman J, Borre L, Hnasko T, Trussell L, et al. Presynaptic regulation of quantal size: K+/H+ exchange stimulates vesicular glutamate transport. Nat Neurosci. 2011;14:1285-92 pubmed publisher
Andersen A, Bentzen B, Salling H, Klingberg H, Kanneworff M, Grunnet M, et al. The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na(+)/H(+) exchanger NHE1. Cell Physiol Biochem. 2011;28:13-24 pubmed publisher
Kumai Y, Perry S. Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water. Am J Physiol Regul Integr Comp Physiol. 2011;301:R1517-28 pubmed publisher
Chao T, Raines R. Mechanism of ribonuclease A endocytosis: analogies to cell-penetrating peptides. Biochemistry. 2011;50:8374-82 pubmed publisher
Castañeda Corral G, Rocha Gonzalez H, Godínez Chaparro B, Jimenez Andrade J, Granados Soto V. Role of the spinal Na+/H+ exchanger in formalin-induced nociception. Neurosci Lett. 2011;501:4-9 pubmed publisher
Rummer J, Brauner C. Plasma-accessible carbonic anhydrase at the tissue of a teleost fish may greatly enhance oxygen delivery: in vitro evidence in rainbow trout, Oncorhynchus mykiss. J Exp Biol. 2011;214:2319-28 pubmed publisher
Erdogan S, Cetinkaya A, Tuli A, Yilmaz E, Dogan A. Changes in the activity of defense mechanisms against induced acidosis during meiotic maturation in mouse oocytes. Theriogenology. 2011;75:1057-66 pubmed publisher
Maxwell C, Spangenberg R, Hoek J, Silberstein S, Oshinsky M. Acetate causes alcohol hangover headache in rats. PLoS ONE. 2010;5:e15963 pubmed publisher
Faul E, Wanjalla C, Suthar M, Gale M, Wirblich C, Schnell M. Rabies virus infection induces type I interferon production in an IPS-1 dependent manner while dendritic cell activation relies on IFNAR signaling. PLoS Pathog. 2010;6:e1001016 pubmed publisher
Heikkilä O, Susi P, Tevaluoto T, Härmä H, Marjomaki V, Hyypia T, et al. Internalization of coxsackievirus A9 is mediated by {beta}2-microglobulin, dynamin, and Arf6 but not by caveolin-1 or clathrin. J Virol. 2010;84:3666-81 pubmed publisher
Sin W, Moniz D, Ozog M, Tyler J, Numata M, Church J. Regulation of early neurite morphogenesis by the Na+/H+ exchanger NHE1. J Neurosci. 2009;29:8946-59 pubmed publisher
Watts B, Good D. Apical membrane Na+/H+ exchange in rat medullary thick ascending limb. pH-dependence and inhibition by hyperosmolality. J Biol Chem. 1994;269:20250-5 pubmed
Abrahamse S, Vis A, Bindels R, Van Os C. Regulation of intracellular pH in crypt cells from rabbit distal colon. Am J Physiol. 1994;267:G409-15 pubmed
product information
Catalog Number :
A3085
Product Name :
5-(N-Ethyl-N-isopropyl)amiloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA