product summary
company name :
Selleck Chemicals
product type :
chemical
product name :
BKM120 (NVP-BKM120)
catalog :
S2247
quantity :
10 g
more info or order :
citations: 6
Reference
Rodgers S, Ooms L, Oorschot V, Schittenhelm R, Nguyen E, Hamila S, et al. INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer. Nat Commun. 2021;12:3140 pubmed publisher
Lake C, Voss K, Bauman B, Pohida K, Jiang T, Dveksler G, et al. TIM-3 drives temporal differences in restimulation-induced cell death sensitivity in effector CD8+ T cells in conjunction with CEACAM1. Cell Death Dis. 2021;12:400 pubmed publisher
Beck A, Cho E, White J, Paemka L, Li T, Gu V, et al. AP-2α Regulates S-Phase and Is a Marker for Sensitivity to PI3K Inhibitor Buparlisib in Colon Cancer. Mol Cancer Res. 2021;19:1156-1167 pubmed publisher
Shan L, Liu W, Zhan Y. Sulfated polysaccharide of Sepiella maindroni ink targets Akt and overcomes resistance to the FGFR inhibitor AZD4547 in bladder cancer. Aging (Albany NY). 2019;11:7780-7795 pubmed publisher
Zhang F, Virshup D, Cheong J. Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis. Oncogene. 2018;37:363-376 pubmed publisher
Wolman M, de Groh E, McBride S, Jongens T, Granato M, Epstein J. Modulation of cAMP and ras signaling pathways improves distinct behavioral deficits in a zebrafish model of neurofibromatosis type 1. Cell Rep. 2014;8:1265-70 pubmed publisher
product information
Catalog Number :
S2247
Product Name :
BKM120 (NVP-BKM120)
Synonyms :
NVP-BKM120
Target :
PI3K
CAS Number :
944396-07-0, 1312445-63-8 (HCl), 1370351-44-2 (0.5H2O)
Formula :
C18H21F3N6O2
Quantity :
10 g
Description :
BKM120 (NVP-BKM120) is a bioavailable specific oral pan-class I phosphatidylinositol 3-kinase (PI3K) kinase inhibitor. Find all the information about BKM120 (NVP-BKM120) for cell signaling research.
Product Type :
Chemical
more info or order :
company information
Selleck Chemicals
2626 South Loop West, Suite 225
Houston, TX 77054
enquiry@selleckchem.com
http://www.selleckchem.com
877 796-6397
headquarters: USA