product summary
company name :
Selleck Chemicals
product type :
chemical
product name :
EX 527
catalog :
S1541
quantity :
10 g
price :
11,700.00 USD
more info or order :
citations: 4
Reference
Wang X, Gao Y, Tian N, Zhu Z, Wang T, Xu J, et al. Astragaloside IV represses high glucose-induced mesangial cells activation by enhancing autophagy via SIRT1 deacetylation of NF-κB p65 subunit. Drug Des Devel Ther. 2018;12:2971-2980 pubmed publisher
Pan W, Yu H, Huang S, Zhu P. Resveratrol Protects against TNF-α-Induced Injury in Human Umbilical Endothelial Cells through Promoting Sirtuin-1-Induced Repression of NF-KB and p38 MAPK. PLoS ONE. 2016;11:e0147034 pubmed publisher
Ohata Y, Matsukawa S, Moriyama Y, Michiue T, Morimoto K, Sato Y, et al. Sirtuin inhibitor Ex-527 causes neural tube defects, ventral edema formations, and gastrointestinal malformations in Xenopus laevis embryos. Dev Growth Differ. 2014;56:460-8 pubmed publisher
Li Y, Tsun A, Gao Z, Han Z, Gao Y, Li Z, et al. 60-kDa Tat-interactive protein (TIP60) positively regulates Th-inducing POK (ThPOK)-mediated repression of eomesodermin in human CD4+ T cells. J Biol Chem. 2013;288:15537-46 pubmed publisher
product information
Catalog Number :
S1541
Product Name :
EX 527
Synonyms :
SEN0014196
Target :
Sirtuin
CAS Number :
49843-98-3
Formula :
C13H13ClN2O
Quantity :
10 g
List Price :
11,700.00 USD
Description :
EX 527 is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor with an IC50 of 38 nM. Find all the information about EX 527 for cell signaling research.
Product Type :
Chemical
more info or order :
company information
Selleck Chemicals
2626 South Loop West, Suite 225
Houston, TX 77054
enquiry@selleckchem.com
http://www.selleckchem.com
877 796-6397
headquarters: USA