Regorafenib (BAY 73-4506) | Selleck Chemicals S1178 product information

product summary

company name :

Selleck Chemicals

product type :

chemical

product name :

Regorafenib (BAY 73-4506)

catalog :

S1178

quantity :

10 g

price :

32,700.00 USD

more info or order :

Selleck Chemicals product webpage

citations: 2

Reference
Wang J, Mouradov D, Wang X, Jorissen R, Chambers M, Zimmerman L, et al. Colorectal Cancer Cell Line Proteomes Are Representative of Primary Tumors and Predict Drug Sensitivity. Gastroenterology. 2017;153:1082-1095 pubmed publisher
Weng Z, Luo Y, Yang X, Greenhaw J, Li H, Xie L, et al. Regorafenib impairs mitochondrial functions, activates AMP-activated protein kinase, induces autophagy, and causes rat hepatocyte necrosis. Toxicology. 2015;327:10-21 pubmed publisher

product information

Catalog Number :

S1178

Product Name :

Regorafenib (BAY 73-4506)

Synonyms :

BAY 73-4506

Target :

c-Kit

CAS Number :

755037-03-7, 835621-07-3 (HCl), 835621-08-4 (methanesulfonate)

Formula :

C21H15ClF4N4O3

Quantity :

10 g

List Price :

32,700.00 USD

Description :

Regorafenib is a multi-kinase inhibitor for VEGFR1, VEGFR2, VEGF3, PDGFRM-NM-2, Kit, RET and RAF-1 with IC50 of 13 nM, 4.2 nM, 46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. Find all the information about Regorafenib (BAY 73-4506) for cell signaling research.

Product Type :

Chemical

more info or order :

Selleck Chemicals product webpage