Rapamycin (Sirolimus) | Selleck Chemicals S1039 product information

product summary

company name :

Selleck Chemicals

product type :

chemical

product name :

Rapamycin (Sirolimus)

catalog :

S1039

quantity :

10 g

price :

7,700.00 USD

more info or order :

Selleck Chemicals product webpage

citations: 10

Reference
Huang X, Gan G, Wang X, Xu T, Xie W. The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Autophagy. 2019;15:1258-1279 pubmed publisher
Wang X, Gao Y, Tian N, Zhu Z, Wang T, Xu J, et al. Astragaloside IV represses high glucose-induced mesangial cells activation by enhancing autophagy via SIRT1 deacetylation of NF-κB p65 subunit. Drug Des Devel Ther. 2018;12:2971-2980 pubmed publisher
Urano Y, Mori C, Fuji A, Konno K, Yamamoto T, Yashirogi S, et al. 6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway. Autophagy. 2018;14:1943-1958 pubmed publisher
Cao Y, Chen M, Tang D, Yan H, Ding X, Zhou F, et al. The proton pump inhibitor pantoprazole disrupts protein degradation systems and sensitizes cancer cells to death under various stresses. Cell Death Dis. 2018;9:604 pubmed publisher
Fu R, Deng Q, Zhang H, Hu X, Li Y, Liu Y, et al. A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3. Cell Death Dis. 2018;9:243 pubmed publisher
Choi J, Kim H, Bae Y, Cheong H. REP1 Modulates Autophagy and Macropinocytosis to Enhance Cancer Cell Survival. Int J Mol Sci. 2017;18: pubmed publisher
Sung S, Choi J, Cheong H. Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras. Oncotarget. 2015;6:40405-17 pubmed publisher
Zucal C, D Agostino V, Casini A, Mantelli B, Thongon N, Soncini D, et al. EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition. BMC Cancer. 2015;15:855 pubmed publisher
Matsumoto M, Seike M, Noro R, Soeno C, Sugano T, Takeuchi S, et al. Control of the MYC-eIF4E axis plus mTOR inhibitor treatment in small cell lung cancer. BMC Cancer. 2015;15:241 pubmed publisher
Huang C, Sheng S, Li R, Sun X, Liu J, Huang G. Lactate promotes resistance to glucose starvation via upregulation of Bcl-2 mediated by mTOR activation. Oncol Rep. 2015;33:875-84 pubmed publisher

product information

Catalog Number :

S1039

Product Name :

Rapamycin (Sirolimus)

Synonyms :

Sirolimus

Target :

mTOR

CAS Number :

53123-88-9, 1179372-35-0, 1189166-54-8, 1233221-34-5, 1353039-01-6

Formula :

C51H79NO13

Quantity :

10 g

List Price :

7,700.00 USD

Description :

Rapamycin also known as Sirolimus & Rapamune is an mTOR inhibitor. Rapamycin Sirolimus inhibits cell motility by suppression of mTOR-mediated pathways. Find all the information about Rapamycin (Sirolimus) for cell signaling research.

Product Type :

Chemical

more info or order :

Selleck Chemicals product webpage