product summary
company name :
Selleck Chemicals
product type :
chemical
product name :
Perifosine
catalog :
S1037
quantity :
10 g
price :
24,000.00 USD
more info or order :
citations: 8
Reference
Dong Y, Pu K, Duan W, Chen H, Chen L, Wang Y. Involvement of Akt/CREB signaling pathways in the protective effect of EPA against interleukin-1β-induced cytotoxicity and BDNF down-regulation in cultured rat hippocampal neurons. BMC Neurosci. 2018;19:52 pubmed publisher
Shen M, Cao Y, Jiang Y, Wei Y, Liu H. Melatonin protects mouse granulosa cells against oxidative damage by inhibiting FOXO1-mediated autophagy: Implication of an antioxidation-independent mechanism. Redox Biol. 2018;18:138-157 pubmed publisher
Huang C, Sheng S, Li R, Sun X, Liu J, Huang G. Lactate promotes resistance to glucose starvation via upregulation of Bcl-2 mediated by mTOR activation. Oncol Rep. 2015;33:875-84 pubmed publisher
Tomiyasu H, Goto Koshino Y, Fujino Y, Ohno K, Tsujimoto H. Antitumour effect and modulation of expression of the ABCB1 gene by perifosine in canine lymphoid tumour cell lines. Vet J. 2014;201:83-90 pubmed publisher
Hou X, Chen X, Zhang P, Fan Y, Ma A, Pang T, et al. Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells. Biochimie. 2014;101:50-9 pubmed publisher
Cheshenko N, Trepanier J, Stefanidou M, Buckley N, Gonzalez P, Jacobs W, et al. HSV activates Akt to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression. FASEB J. 2013;27:2584-99 pubmed publisher
O Malley Y, Lal G, Howe J, Weigel R, Komorowski R, Shilyansky J, et al. Invasion in follicular thyroid cancer cell lines is mediated by EphA2 and pAkt. Surgery. 2012;152:1218-24 pubmed publisher
Lin K, Rossi L, Boles N, Hall B, George T, Goodell M. CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway. PLoS Biol. 2011;9:e1001148 pubmed publisher
product information
Catalog Number :
S1037
Product Name :
Perifosine
Synonyms :
KRX-0401
Target :
Akt
CAS Number :
157716-52-4
Formula :
C25H52NO4P
Quantity :
10 g
List Price :
24,000.00 USD
Description :
Perifosine is an Akt inhibitor. the antiproliferative properties of perifosine with an IC50 of 0.6M-bM-^@M-^S8.9 uM. Find all the information about Perifosine for cell signaling research.
Product Type :
Chemical
more info or order :
company information
Selleck Chemicals
2626 South Loop West, Suite 225
Houston, TX 77054
enquiry@selleckchem.com
http://www.selleckchem.com
877 796-6397
headquarters: USA