product summary
company name :
Selleck Chemicals
product type :
chemical
product name :
Gefitinib (Iressa)
catalog :
S1025
quantity :
10 g
more info or order :
citations: 7
Reference
Glorieux C, Xia X, He Y, Hu Y, Cremer K, Robert A, et al. Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling. Redox Biol. 2021;38:101780 pubmed publisher
Sachs N, Papaspyropoulos A, Zomer van Ommen D, Heo I, Böttinger L, Klay D, et al. Long-term expanding human airway organoids for disease modeling. EMBO J. 2019;38: pubmed publisher
Han F, Li C, Cai Z, Zhang X, Jin G, Zhang W, et al. The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance. Nat Commun. 2018;9:4728 pubmed publisher
Sechet E, Telford E, Bonamy C, Sansonetti P, Sperandio B. Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3. Proc Natl Acad Sci U S A. 2018;115:E9869-E9878 pubmed publisher
Tavolari S, Munarini A, Storci G, Laufer S, Chieco P, Guarnieri T. The decrease of cell membrane fluidity by the non-steroidal anti-inflammatory drug Licofelone inhibits epidermal growth factor receptor signalling and triggers apoptosis in HCA-7 colon cancer cells. Cancer Lett. 2012;321:187-94 pubmed publisher
Prahallad A, Sun C, Huang S, Di Nicolantonio F, Salazar R, Zecchin D, et al. Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. Nature. 2012;483:100-3 pubmed publisher
Kitajima S, Miki T, Takegami Y, Kido Y, Noda M, Hara E, et al. Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling. Oncogene. 2011;30:737-50 pubmed publisher
product information
Catalog Number :
S1025
Product Name :
Gefitinib (Iressa)
Synonyms :
ZD-1839, Iressa
Target :
EGFR
CAS Number :
184475-35-2, 184475-55-6 (HCl)
Formula :
C22H24ClFN4O3
Quantity :
10 g
Description :
Gefitinib (Iressa) also known as ZD-1839 & Iressa is a novel potent EGFR tyrosine kinase phosphorylation inhibitor with IC50 of 37, 26 and 57 nM. Find all the information about Gefitinib (Iressa) for cell signaling research.
Product Type :
Chemical
more info or order :
company information
Selleck Chemicals
2626 South Loop West, Suite 225
Houston, TX 77054
enquiry@selleckchem.com
http://www.selleckchem.com
877 796-6397
headquarters: USA