product summary
company name :
Selleck Chemicals
product type :
chemical
product name :
CI-1040 (PD184352)
catalog :
S1020
quantity :
10 g
price :
17,000.00 USD
more info or order :
citations: 8
Reference
Bordignon P, Bottoni G, Xu X, Popescu A, Truan Z, Guenova E, et al. Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant. Cell Rep. 2019;28:2358-2372.e6 pubmed publisher
LeBlanc L, Lee B, Yu A, Kim M, Kambhampati A, Dupont S, et al. Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation. elife. 2018;7: pubmed publisher
Sharma V, Young L, Cavadas M, Owen K. Registered Report: COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. elife. 2016;5: pubmed publisher
Wang H, Leinwand L, Anseth K. Roles of transforming growth factor-?1 and OB-cadherin in porcine cardiac valve myofibroblast differentiation. FASEB J. 2014;28:4551-62 pubmed publisher
Knelson E, Gaviglio A, Tewari A, Armstrong M, Mythreye K, Blobe G. Type III TGF-β receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma. J Clin Invest. 2013;123:4786-98 pubmed
Willoughby L, Schlosser T, Manning S, Parisot J, Street I, Richardson H, et al. An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery. Dis Model Mech. 2013;6:521-9 pubmed publisher
Burkhard K, Shapiro P. Use of inhibitors in the study of MAP kinases. Methods Mol Biol. 2010;661:107-22 pubmed publisher
Gelmedin V, Spiliotis M, Brehm K. Molecular characterisation of MEK1/2- and MKK3/6-like mitogen-activated protein kinase kinases (MAPKK) from the fox tapeworm Echinococcus multilocularis. Int J Parasitol. 2010;40:555-67 pubmed publisher
product information
Catalog Number :
S1020
Product Name :
CI-1040 (PD184352)
Synonyms :
PD184352
Target :
MEK
CAS Number :
212631-79-3
Formula :
C17H14ClF2IN2O2
Quantity :
10 g
List Price :
17,000.00 USD
Description :
CI-1040 (PD 184352) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM. Find all the information about CI-1040 (PD184352) for cell signaling research.
Product Type :
Chemical
more info or order :
company information
Selleck Chemicals
2626 South Loop West, Suite 225
Houston, TX 77054
enquiry@selleckchem.com
http://www.selleckchem.com
877 796-6397
headquarters: USA