BEZ235 (NVP-BEZ235) | Selleck Chemicals S1009 product information

product summary

company name :

Selleck Chemicals

product type :

chemical

product name :

BEZ235 (NVP-BEZ235)

catalog :

S1009

quantity :

10 g

price :

5,220.00 USD

more info or order :

Selleck Chemicals product webpage

citations: 5

Reference
Lu X, Horner J, Paul E, Shang X, Troncoso P, Deng P, et al. Effective combinatorial immunotherapy for castration-resistant prostate cancer. Nature. 2017;543:728-732 pubmed publisher
Briffa R, Um I, Faratian D, Zhou Y, Turnbull A, Langdon S, et al. Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers. PLoS ONE. 2015;10:e0144708 pubmed publisher
Gardner E, Connis N, Poirier J, Cope L, Dobromilskaya I, Gallia G, et al. Rapamycin rescues ABT-737 efficacy in small cell lung cancer. Cancer Res. 2014;74:2846-56 pubmed publisher
Xia M, Gonzalez P, Li C, Meng G, Jiang A, Wang H, et al. Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. J Virol. 2014;88:5152-64 pubmed publisher
Urata S, Ngo N, de la Torre J. The PI3K/Akt pathway contributes to arenavirus budding. J Virol. 2012;86:4578-85 pubmed publisher

product information

Catalog Number :

S1009

Product Name :

BEZ235 (NVP-BEZ235)

Synonyms :

NVP-BEZ235

Target :

PI3K

CAS Number :

915019-65-7, 1028385-32-1 (4-methylbenzenesulfonate)

Formula :

C30H23N5O

Quantity :

10 g

List Price :

5,220.00 USD

Description :

BEZ235 (NVP-BEZ235) is a dual ATP-competitive phosphatidylinositol 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor of p110M-NM-1, p110M-NM-3, p110M-NM-4 and p110M-NM-2 with IC50 of 4, 5, 7 and 75 nM, respectively. Find all the information about BEZ235 (NVP-BEZ235) for cell signaling research.

Product Type :

Chemical

more info or order :

Selleck Chemicals product webpage