| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; loading ...; fig 3b
| Lei T, Zhang P, Zhang X, Xiao X, Zhang J, Qiu T, et al. Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation. Nat Commun. 2018;9:1876 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 1d
| Somyajit K, Gupta R, Sedlackova H, Neelsen K, Ochs F, Rask M, et al. Redox-sensitive alteration of replisome architecture safeguards genome integrity. Science. 2017;358:797-802 pubmed publisher |
- western blot; human; loading ...; fig 3a
| He D, Ren B, Liu S, Tan L, Cieply K, Tseng G, et al. Oncogenic activity of amplified miniature chromosome maintenance 8 in human malignancies. Oncogene. 2017;36:3629-3639 pubmed publisher |
- western blot; mouse; loading ...; fig 4h
| Endorf E, Qing H, Aono J, Terami N, Doyon G, Hyzny E, et al. Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes. Arterioscler Thromb Vasc Biol. 2017;37:301-311 pubmed publisher |
- chromatin immunoprecipitation; human; loading ...; fig 7a
- immunocytochemistry; human; loading ...; fig 5a
- western blot; human; loading ...; fig 5c
| Lu F, Wu X, Yin F, Chia Fang Lee C, Yu M, Mihaylov I, et al. Regulation of DNA replication and chromosomal polyploidy by the MLL-WDR5-RBBP5 methyltransferases. Biol Open. 2016;5:1449-1460 pubmed publisher |
- western blot; Xenopus laevis; 1:1000; fig 8
| Simon A, Sannino V, Costanzo V, Pellegrini L. Structure of human Cdc45 and implications for CMG helicase function. Nat Commun. 2016;7:11638 pubmed publisher |
- immunoprecipitation; human; fig 6
- immunocytochemistry; human; fig 7
- western blot; human; 1:1000; fig 1
| Huang Y, Amin A, Qin Y, Wang Z, Jiang H, Liang L, et al. A Role of hIPI3 in DNA Replication Licensing in Human Cells. PLoS ONE. 2016;11:e0151803 pubmed publisher |
- western blot; human; 1:1000; fig 5
| Passerini V, Ozeri Galai E, de Pagter M, Donnelly N, Schmalbrock S, Kloosterman W, et al. The presence of extra chromosomes leads to genomic instability. Nat Commun. 2016;7:10754 pubmed publisher |
- western blot; human; fig 2
| Benatti P, Belluti S, Miotto B, Neusiedler J, Dolfini D, Drac M, et al. Direct non transcriptional role of NF-Y in DNA replication. Biochim Biophys Acta. 2016;1863:673-85 pubmed publisher |
- western blot; human; fig 6
| Kanu N, Grönroos E, Martinez P, Burrell R, Yi Goh X, Bartkova J, et al. SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. Oncogene. 2015;34:5699-708 pubmed publisher |
- western blot; human; fig 3a
| Wu M, Lu W, Santos R, Frattini M, Kelly T. Geminin inhibits a late step in the formation of human pre-replicative complexes. J Biol Chem. 2014;289:30810-21 pubmed publisher |
- immunocytochemistry; human; 1:200
| Liu Y, Jiang Y, Wang B, Hao J, Shang L, Zhang T, et al. A panel of protein markers for the early detection of lung cancer with bronchial brushing specimens. Cancer Cytopathol. 2014;122:833-41 pubmed publisher |
| Kusunoki S, Ishimi Y. Interaction of human minichromosome maintenance protein-binding protein with minichromosome maintenance 2-7. FEBS J. 2014;281:1057-67 pubmed publisher |
- western blot; human; 1:1000
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| Polasek Sedlackova H, Miller T, Krejci J, Rask M, Lukas J. Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes. Nat Commun. 2022;13:6090 pubmed publisher |
| Kumar R, Rao G. Novel Role of Prereplication Complex Component Cell Division Cycle 6 in Retinal Neovascularization. Arterioscler Thromb Vasc Biol. 2022;42:407-427 pubmed publisher |
| Miyata S, Saku N, Akiyama S, Javaregowda P, Ite K, Takashima N, et al. Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI). Stem Cell Res Ther. 2022;13:6 pubmed publisher |
| Maskey R, Kim M, Baker D, Childs B, Malureanu L, Jeganathan K, et al. Spartan deficiency causes genomic instability and progeroid phenotypes. Nat Commun. 2014;5:5744 pubmed publisher |
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| Perez K, Martínez F, Cosme Cruz R, Perez Crespo N, Tang Q. A short cis-acting motif in the M112-113 promoter region is essential for IE3 to activate M112-113 gene expression and is important for murine cytomegalovirus replication. J Virol. 2013;87:2639-47 pubmed publisher |
| Li Y, Xiao H, de Renty C, Jaramillo Lambert A, Han Z, DePamphilis M, et al. The involvement of acidic nucleoplasmic DNA-binding protein (And-1) in the regulation of prereplicative complex (pre-RC) assembly in human cells. J Biol Chem. 2012;287:42469-79 pubmed publisher |
| Karakaya K, Herbst F, Ball C, Glimm H, Krämer A, Loffler H. Overexpression of EVI1 interferes with cytokinesis and leads to accumulation of cells with supernumerary centrosomes in G0/1 phase. Cell Cycle. 2012;11:3492-503 pubmed publisher |
| Watanabe E, Ohara R, Ishimi Y. Effect of an MCM4 mutation that causes tumours in mouse on human MCM4/6/7 complex formation. J Biochem. 2012;152:191-8 pubmed publisher |
| Liu Y, Jiang Y, Hao J, Lu S, Zhang T, Shang L, et al. Prognostic significance of MCM7 expression in the bronchial brushings of patients with non-small cell lung cancer (NSCLC). Lung Cancer. 2012;77:176-82 pubmed publisher |
| Mart nez F, Tang Q. Leucine zipper domain is required for Kaposi sarcoma-associated herpesvirus (KSHV) K-bZIP protein to interact with histone deacetylase and is important for KSHV replication. J Biol Chem. 2012;287:15622-34 pubmed publisher |
| Hudson R, Yi M, Esposito D, Watkins S, Hurwitz A, Yfantis H, et al. MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer. Nucleic Acids Res. 2012;40:3689-703 pubmed publisher |
| Jones M, Colnaghi L, Huang T. Dysregulation of DNA polymerase ? recruitment to replication forks results in genomic instability. EMBO J. 2012;31:908-18 pubmed publisher |
| Di Paola D, Zannis Hadjopoulos M. Comparative analysis of pre-replication complex proteins in transformed and normal cells. J Cell Biochem. 2012;113:1333-47 pubmed publisher |
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| Findeisen H, Pearson K, Gizard F, Zhao Y, Qing H, Jones K, et al. Oxidative stress accumulates in adipose tissue during aging and inhibits adipogenesis. PLoS ONE. 2011;6:e18532 pubmed publisher |
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| Lubelsky Y, Sasaki T, Kuipers M, Lucas I, Le Beau M, Carignon S, et al. Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone. Nucleic Acids Res. 2011;39:3141-55 pubmed publisher |
| Zhang J, Yu L, Wu X, Zou L, Sou K, Wei Z, et al. The interacting domains of hCdt1 and hMcm6 involved in the chromatin loading of the MCM complex in human cells. Cell Cycle. 2010;9:4848-57 pubmed |
| Hashimoto Y, Ray Chaudhuri A, Lopes M, Costanzo V. Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis. Nat Struct Mol Biol. 2010;17:1305-11 pubmed publisher |
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| Liu J, Lyon C, Hsueh W, Law R. A Dominant-Negative PPARgamma Mutant Promotes Cell Cycle Progression and Cell Growth in Vascular Smooth Muscle Cells. PPAR Res. 2009;2009:438673 pubmed publisher |
| Numata Y, Ishihara S, Hasegawa N, Nozaki N, Ishimi Y. Interaction of human MCM2-7 proteins with TIM, TIPIN and Rb. J Biochem. 2010;147:917-27 pubmed publisher |
| Köhler C, Kreuter A, Rozynkowski M, Rahmel T, Uhl W, Tannapfel A, et al. Validation of different replication markers for the detection of beta-cell proliferation in human pancreatic tissue. Regul Pept. 2010;162:115-21 pubmed publisher |
| Garnier D, Loyer P, Ribault C, Guguen Guillouzo C, Corlu A. Cyclin-dependent kinase 1 plays a critical role in DNA replication control during rat liver regeneration. Hepatology. 2009;50:1946-56 pubmed publisher |
| Shen X, Do H, Li Y, Chung W, Tomasz M, de Winter J, et al. Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication. Mol Cell. 2009;35:716-23 pubmed publisher |
| Ishimi Y, Sugiyama T, Nakaya R, Kanamori M, Kohno T, Enomoto T, et al. Effect of heliquinomycin on the activity of human minichromosome maintenance 4/6/7 helicase. FEBS J. 2009;276:3382-91 pubmed publisher |
| Trenz K, Errico A, Costanzo V. Plx1 is required for chromosomal DNA replication under stressful conditions. EMBO J. 2008;27:876-85 pubmed publisher |
| Laitinen S, Martikainen P, Tolonen T, Isola J, Tammela T, Visakorpi T. EZH2, Ki-67 and MCM7 are prognostic markers in prostatectomy treated patients. Int J Cancer. 2008;122:595-602 pubmed |
| Sharma A, Comstock C, Knudsen E, Cao K, Hess Wilson J, Morey L, et al. Retinoblastoma tumor suppressor status is a critical determinant of therapeutic response in prostate cancer cells. Cancer Res. 2007;67:6192-203 pubmed |
| Koch H, Zhang R, Verdoodt B, Bailey A, Zhang C, Yates J, et al. Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach. Cell Cycle. 2007;6:205-17 pubmed |
| Siddiqui H, Fox S, Gunawardena R, Knudsen E. Loss of RB compromises specific heterochromatin modifications and modulates HP1alpha dynamics. J Cell Physiol. 2007;211:131-7 pubmed |
| Karstensen B, Poppelreuther S, Bonin M, Walter M, Iftner T, Stubenrauch F. Gene expression profiles reveal an upregulation of E2F and downregulation of interferon targets by HPV18 but no changes between keratinocytes with integrated or episomal viral genomes. Virology. 2006;353:200-9 pubmed |
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