product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Shc (PG-797) Antibody
catalog :
sc-967
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PG-797
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 1e
Stucky A, Bakshi K, Friedman E, Wang H. Prenatal Cocaine Exposure Upregulates BDNF-TrkB Signaling. PLoS ONE. 2016;11:e0160585 pubmed publisher
  • immunoprecipitation; human; fig 2
Kwon H, Lee J, Jeong K, Jang D, Pak Y. Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation. Biochim Biophys Acta. 2015;1853:1022-34 pubmed publisher
Guo G, Gong K, Beckley N, Zhang Y, Yang X, Chkheidze R, et al. EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation. Nat Cell Biol. 2022;24:1291-1305 pubmed publisher
Seko Y, Fujimura T, Yao T, Taka H, Mineki R, Okumura K, et al. Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis. Sci Rep. 2015;5:13737 pubmed publisher
Benbrook D, Nammalwar B, Long A, Matsumoto H, Singh A, Bunce R, et al. SHetA2 interference with mortalin binding to p66shc and p53 identified using drug-conjugated magnetic microspheres. Invest New Drugs. 2014;32:412-23 pubmed publisher
Chen K, Hsu L, Goto S, Yeh C, Nakano T, Lai C, et al. Adaptor protein Shc acts as an immune-regulator for the LPS-stimulated maturation of bone marrow-derived dendritic cells. BMC Immunol. 2011;12:32 pubmed publisher
Thomas S, Alam R, Lemke N, Schultz L, Gutierrez J, Rempel S. PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling. Neuro Oncol. 2010;12:941-55 pubmed publisher
van Dijk T, Gillemans N, Stein C, Fanis P, Demmers J, van de Corput M, et al. Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases. Mol Cell Biol. 2010;30:260-72 pubmed publisher
Sly L, Hamilton M, Kuroda E, Ho V, Antignano F, Omeis S, et al. SHIP prevents lipopolysaccharide from triggering an antiviral response in mice. Blood. 2009;113:2945-54 pubmed publisher
Di X, Yu L, Moore A, Castro L, Zheng X, Hermon T, et al. A low concentration of genistein induces estrogen receptor-alpha and insulin-like growth factor-I receptor interactions and proliferation in uterine leiomyoma cells. Hum Reprod. 2008;23:1873-83 pubmed publisher
Rolfe K, Cambrey A, Richardson J, Irvine L, Grobbelaar A, Linge C. Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors. BMC Dev Biol. 2007;7:124 pubmed
Rucci N, DiGiacinto C, Orrù L, Millimaggi D, Baron R, Teti A. A novel protein kinase C alpha-dependent signal to ERK1/2 activated by alphaVbeta3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells. J Cell Sci. 2005;118:3263-75 pubmed
product information
Product Name :
Shc (PG-797) Antibody
Gene Name :
SHC1
Size :
200 µg/ml
Catalog Number :
sc-967
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Shc
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM
Epitope :
476-583 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA