Izadi D, Layton T, Williams L, McCann F, Cabrita M, Espirito Santo A, et al. Identification of TNFR2 and IL-33 as therapeutic targets in localized fibrosis. Sci Adv. 2019;5:eaay0370 pubmed publisher

Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed publisher

Han L, Wang L, Tang S, Yuan L, Wu S, Du X, et al. ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior. J Neuroinflammation. 2018;15:246 pubmed publisher

Mironets E, Osei Owusu P, Bracchi Ricard V, Fischer R, Owens E, Ricard J, et al. Soluble TNFα Signaling within the Spinal Cord Contributes to the Development of Autonomic Dysreflexia and Ensuing Vascular and Immune Dysfunction after Spinal Cord Injury. J Neurosci. 2018;38:4146-4162 pubmed publisher

Zhao L, Zhang B. Doxorubicin induces cardiotoxicity through upregulation of death receptors mediated apoptosis in cardiomyocytes. Sci Rep. 2017;7:44735 pubmed publisher

Kupka S, De Miguel D, Dráber P, Martino L, Surinova S, Rittinger K, et al. SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. Cell Rep. 2016;16:2271-80 pubmed publisher

Wu S, Kanda T, Nakamoto S, Jiang X, Nakamura M, Sasaki R, et al. Cooperative effects of hepatitis B virus and TNF may play important roles in the activation of metabolic pathways through the activation of NF-?B. Int J Mol Med. 2016;38:475-81 pubmed publisher

Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Cell Rep. 2016;15:1481-1492 pubmed publisher

Emmerich C, Bakshi S, Kelsall I, Ortiz Guerrero J, Shpiro N, Cohen P. Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling. Biochem Biophys Res Commun. 2016;474:452-461 pubmed publisher

Chhibber Goel J, Coleman Vaughan C, Agrawal V, Sawhney N, Hickey E, Powell J, et al. γ-Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling. J Biol Chem. 2016;291:5971-85 pubmed publisher

Lin C, Huang P, Lai C, Chen J, Lin S, Chen J. Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1. PLoS ONE. 2015;10:e0143686 pubmed publisher

Yang H, Zhang M, Wang X, Zhang H, Zhang J, Jing L, et al. TNF Accelerates Death of Mandibular Condyle Chondrocytes in Rats with Biomechanical Stimulation-Induced Temporomandibular Joint Disease. PLoS ONE. 2015;10:e0141774 pubmed publisher

Lee C, Yang Y, Chen C, Liu J. Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death. Oncogene. 2016;35:1988-95 pubmed publisher

Clark P, Kim R, Pober J, Kluger M. Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases. PLoS ONE. 2015;10:e0120075 pubmed publisher

Opperman C, Sishi B. Tumor necrosis factor alpha stimulates p62 accumulation and enhances proteasome activity independently of ROS. Cell Biol Toxicol. 2015;31:83-94 pubmed publisher

Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, et al. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling. J Biol Chem. 2015;290:10395-405 pubmed publisher

Morlé A, Garrido C, Micheau O. Hyperthermia restores apoptosis induced by death receptors through aggregation-induced c-FLIP cytosolic depletion. Cell Death Dis. 2015;6:e1633 pubmed publisher

Gao S, Andreeva K, Cooper N. Ischemia-reperfusion injury of the retina is linked to necroptosis via the ERK1/2-RIP3 pathway. Mol Vis. 2014;20:1374-87 pubmed

Varley K, Gertz J, Roberts B, Davis N, Bowling K, Kirby M, et al. Recurrent read-through fusion transcripts in breast cancer. Breast Cancer Res Treat. 2014;146:287-97 pubmed publisher

Li M, Liu Y, Xia F, Wu Z, Deng L, Jiang R, et al. Progranulin is required for proper ER stress response and inhibits ER stress-mediated apoptosis through TNFR2. Cell Signal. 2014;26:1539-48 pubmed publisher

Kim T, Kang Y, Park Z, Kim Y, Hong S, Oh S, et al. SH3RF2 functions as an oncogene by mediating PAK4 protein stability. Carcinogenesis. 2014;35:624-34 pubmed publisher

Luce A, Courtin A, Levalois C, Altmeyer Morel S, Romeo P, Chevillard S, et al. Death receptor pathways mediate targeted and non-targeted effects of ionizing radiations in breast cancer cells. Carcinogenesis. 2009;30:432-9 pubmed publisher

Kabashima A, Hirsova P, Bronk S, Hernandez M, Truty M, Rizvi S, et al. Fibroblast growth factor receptor inhibition induces loss of matrix MCL1 and necrosis in cholangiocarcinoma. J Hepatol. 2018;68:1228-1238 pubmed publisher

Yi H, Liu S, Kashiwagi Y, Ikegami D, Huang W, Kanda H, et al. Phosphorylated CCAAT/Enhancer Binding Protein β Contributes to Rat HIV-Related Neuropathic Pain: In Vitro and In Vivo Studies. J Neurosci. 2018;38:555-574 pubmed publisher

Chang X, Wang L, Wang Z, Wu S, Zhu X, Hu S, et al. TRADD mediates the tumor necrosis factor-induced apoptosis of L929 cells in the absence of RIP3. Sci Rep. 2017;7:16111 pubmed publisher

Imbert P, Louche A, Luizet J, Grandjean T, Bigot S, Wood T, et al. A Pseudomonas aeruginosa TIR effector mediates immune evasion by targeting UBAP1 and TLR adaptors. EMBO J. 2017;36:1869-1887 pubmed publisher

Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, et al. Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis. Sci Rep. 2017;7:44754 pubmed publisher

Zilberman Rudenko J, Shawver L, Wessel A, Luo Y, Pelletier M, Tsai W, et al. Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease. Proc Natl Acad Sci U S A. 2016;113:1612-7 pubmed publisher

Estornes Y, Aguileta M, Dubuisson C, De Keyser J, Goossens V, Kersse K, et al. RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions. Cell Death Dis. 2014;5:e1555 pubmed publisher

Choi J, Devkota S, Sung Y, Lee H. EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-?B activity. Oncotarget. 2013;4:2383-96 pubmed

Sosna J, Voigt S, Mathieu S, Lange A, Thon L, Davarnia P, et al. TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death. Cell Mol Life Sci. 2014;71:331-48 pubmed publisher

Aebischer J, Sturny R, Andrieu D, Rieusset A, Schaller F, Geib S, et al. Necdin protects embryonic motoneurons from programmed cell death. PLoS ONE. 2011;6:e23764 pubmed publisher

Zhang X, Kainz V, Burstein R, Levy D. Tumor necrosis factor-? induces sensitization of meningeal nociceptors mediated via local COX and p38 MAP kinase actions. Pain. 2011;152:140-9 pubmed publisher

Bristol J, Robinson A, Barlow E, Kenney S. The Epstein-Barr virus BZLF1 protein inhibits tumor necrosis factor receptor 1 expression through effects on cellular C/EBP proteins. J Virol. 2010;84:12362-74 pubmed publisher

Bristol J, Morrison T, Kenney S. CCAAT/enhancer binding proteins alpha and beta regulate the tumor necrosis factor receptor 1 gene promoter. Mol Immunol. 2009;46:2706-13 pubmed publisher

Ding B, Kirkiles Smith N, Pober J. FOXO3a regulates oxygen-responsive expression of tumor necrosis factor receptor 2 in human dermal microvascular endothelial cells. J Biol Chem. 2009;284:19331-9 pubmed publisher

Chen H, Pan K, Tang M, Chui Y, Chen L, Su Z, et al. Comparative proteomic analysis reveals differentially expressed proteins regulated by a potential tumor promoter, BRE, in human esophageal carcinoma cells. Biochem Cell Biol. 2008;86:302-11 pubmed publisher

Braun F, Fecker L, Schwarz C, Walden P, Assaf C, Dürkop H, et al. Blockade of death receptor-mediated pathways early in the signaling cascade coincides with distinct apoptosis resistance in cutaneous T-cell lymphoma cells. J Invest Dermatol. 2007;127:2425-37 pubmed

Inoue Y, Nakayama Y, Sako T, Minagawa N, Abe Y, Nagato M, et al. 4- [3,5-bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) induced fas expression and activated caspase-3 and -8 in a DLD-1 colon cancer cell line. In Vivo. 2007;21:381-7 pubmed

Gordon G, Mani M, Mukhopadhyay L, Dong L, Yeap B, Sugarbaker D, et al. Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma. J Pathol. 2007;211:439-46 pubmed

Bennett R, Blalock W, Abtahi D, Pan Y, Moyer S, May W. RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection. Blood. 2006;108:821-9 pubmed

Scheuner D, Patel R, Wang F, Lee K, Kumar K, Wu J, et al. Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis. J Biol Chem. 2006;281:21458-68 pubmed