product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Actin (C-2) Antibody
catalog :
sc-8432
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-2
reactivity :
human, mouse, rat, dogs
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 404
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4g
Singh V, Khalil M, De Benedetti A. The TLK1/Nek1 axis contributes to mitochondrial integrity and apoptosis prevention via phosphorylation of VDAC1. Cell Cycle. 2020;19:363-375 pubmed publisher
  • western blot; mouse; loading ...; fig 2e
Rodríguez Baena F, Redondo García S, Peris Torres C, Martino Echarri E, Fernández Rodríguez R, Plaza Calonge M, et al. ADAMTS1 protease is required for a balanced immune cell repertoire and tumour inflammatory response. Sci Rep. 2018;8:13103 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1d
  • western blot; mouse; 1:1000; fig 1d
Zhang C, Wang C, Jiang M, Gu C, Xiao J, Chen X, et al. Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nat Commun. 2018;9:2745 pubmed publisher
  • western blot; human; fig 4
He M, Yuan H, Tan B, Bai R, Kim H, Bae S, et al. SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells. Oncotarget. 2016;7:75698-75711 pubmed publisher
  • western blot; human; 1:1000; fig 1
Romeo S, Conti A, Polito F, Tomasello C, Barresi V, La Torre D, et al. miRNA regulation of Sirtuin-1 expression in human astrocytoma. Oncol Lett. 2016;12:2992-2998 pubmed
  • western blot; human; 1:5000; fig 1
Zhou S, Han Q, Wang R, Li X, Wang Q, Wang H, et al. PRDX2 protects hepatocellular carcinoma SMMC-7721 cells from oxidative stress. Oncol Lett. 2016;12:2217-2221 pubmed
  • western blot; human; 1:1000; fig 1
Yang X, Zhou X, Tone P, Durkin M, Popescu N. Cooperative antiproliferative effect of coordinated ectopic expression of DLC1 tumor suppressor protein and silencing of MYC oncogene expression in liver cancer cells: Therapeutic implications. Oncol Lett. 2016;12:1591-1596 pubmed
  • western blot; human; 1:500; fig 6
Jin Z, Yan W, Jin H, Ge C, Xu Y. Psoralidin inhibits proliferation and enhances apoptosis of human esophageal carcinoma cells via NF-?B and PI3K/Akt signaling pathways. Oncol Lett. 2016;12:971-976 pubmed
  • western blot; human; 1:200; fig 1
Geng J, Li J, Huang T, Zhao K, Chen Q, Guo W, et al. A novel manganese complex selectively induces malignant glioma cell death by targeting mitochondria. Mol Med Rep. 2016;14:1970-8 pubmed publisher
  • western blot; human; 1:5000; fig 6
Espinoza I, Sakiyama M, Ma T, Fair L, Zhou X, Hassan M, et al. Hypoxia on the Expression of Hepatoma Upregulated Protein in Prostate Cancer Cells. Front Oncol. 2016;6:144 pubmed publisher
  • western blot; mouse; fig 5
Wang T, Pan D, Zhou Z, You Y, Jiang C, Zhao X, et al. Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut. PLoS Pathog. 2016;12:e1005662 pubmed publisher
  • western blot; rat; 1:500; fig 3
Negis Y, Karabay A. Expression of cell cycle proteins in cortical neurons-Correlation with glutamate-induced neurotoxicity. Biofactors. 2016;42:358-67 pubmed publisher
  • western blot; human; 1:1000; fig 5
Liu L, Bai Z, Ma X, Wang T, Yang Y, Zhang Z. Effects of taxol resistance gene 1 expression on the chemosensitivity of SGC-7901 cells to oxaliplatin. Exp Ther Med. 2016;11:846-852 pubmed
  • western blot; mouse; fig 2b
Malecova B, Dall Agnese A, Madaro L, Gatto S, Coutinho Toto P, Albini S, et al. TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells. elife. 2016;5: pubmed publisher
  • western blot; mouse; fig 4
Kim J, Kim E, Lee B, Min J, Song D, Lim J, et al. The effects of Lycii Radicis Cortex on RANKL-induced osteoclast differentiation and activation in RAW 264.7 cells. Int J Mol Med. 2016;37:649-58 pubmed publisher
  • western blot; human; 1:1000; fig 4
Wang Y, Hou H, Li M, Yang Y, Sun L. Anticancer effect of eupatilin on glioma cells through inhibition of the Notch-1 signaling pathway. Mol Med Rep. 2016;13:1141-6 pubmed publisher
  • western blot; mouse; 1:2000; fig 3
Brai E, Marathe S, Astori S, Fredj N, Perry E, Lamy C, et al. Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling. Front Cell Neurosci. 2015;9:447 pubmed publisher
  • western blot; human; 1000 ng/ml; fig 1
Leshchyns ka I, Liew H, Shepherd C, Halliday G, Stevens C, Ke Y, et al. Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease. Nat Commun. 2015;6:8836 pubmed publisher
  • western blot; mouse; fig 1
Cao J, Zhang X, Wang Q, Qiu G, Hou C, Wang J, et al. Smad4 represses the generation of memory-precursor effector T cells but is required for the differentiation of central memory T cells. Cell Death Dis. 2015;6:e1984 pubmed publisher
  • western blot; human; fig 2A
Wang W, Liu H, Dai X, Fang S, Wang X, Zhang Y, et al. p53/PUMA expression in human pulmonary fibroblasts mediates cell activation and migration in silicosis. Sci Rep. 2015;5:16900 pubmed publisher
  • western blot; mouse; 1:5000; fig 2
  • western blot; rat; 1:5000; fig 1
Hu Z, Hu J, Shen W, Kraemer F, Azhar S. A Novel Role of Salt-Inducible Kinase 1 (SIK1) in the Post-Translational Regulation of Scavenger Receptor Class B Type 1 Activity. Biochemistry. 2015;54:6917-30 pubmed publisher
  • immunocytochemistry; dogs; fig 1b
  • western blot; dogs; 1:1000; fig s1d
Archibald A, Al Masri M, Liew Spilger A, McCaffrey L. Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling. Mol Biol Cell. 2015;26:3578-95 pubmed publisher
  • western blot; human; fig 2
Khan I, Zakaria M, Kumar M, Mani P, Chattopadhyay P, Sarkar D, et al. A novel placental like alkaline phosphatase promoter driven transcriptional silencing combined with single chain variable fragment antibody based virosomal delivery for neoplastic cell targeting [corrected]. J Transl Med. 2015;13:254 pubmed publisher
  • western blot; human; fig 5
Zhao L, Tang M, Hu Z, Yan B, Pi W, Li Z, et al. miR-504 mediated down-regulation of nuclear respiratory factor 1 leads to radio-resistance in nasopharyngeal carcinoma. Oncotarget. 2015;6:15995-6018 pubmed
  • western blot; human; fig 3a
Li W, Qiu Y, Zhang H, Tian X, Fang W. P2Y2 Receptor and EGFR Cooperate to Promote Prostate Cancer Cell Invasion via ERK1/2 Pathway. PLoS ONE. 2015;10:e0133165 pubmed publisher
  • western blot; human; fig 6a
Liu R, Fan M, Candas D, Qin L, Zhang X, Eldridge A, et al. CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Mol Cancer Ther. 2015;14:2090-102 pubmed publisher
  • western blot; dogs; 1:50,000; fig 1
Nadeau M, Rico C, Tsoi M, Vivancos M, Filimon S, Paquet M, et al. Pharmacological targeting of valosin containing protein (VCP) induces DNA damage and selectively kills canine lymphoma cells. BMC Cancer. 2015;15:479 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Masuda Y, Takahashi H, Hatakeyama S. TRIM29 regulates the p63-mediated pathway in cervical cancer cells. Biochim Biophys Acta. 2015;1853:2296-305 pubmed publisher
  • immunocytochemistry; mouse; fig 3d
Zhang T, Zhou Y, Qi S, Wang Z, Qian W, Ouyang Y, et al. Nuf2 is required for chromosome segregation during mouse oocyte meiotic maturation. Cell Cycle. 2015;14:2701-10 pubmed publisher
  • western blot; human; fig 1
Pan D, Jiang C, Ma Z, Blonska M, You M, Lin X. MALT1 is required for EGFR-induced NF-?B activation and contributes to EGFR-driven lung cancer progression. Oncogene. 2016;35:919-28 pubmed publisher
  • chromatin immunoprecipitation; human; fig 5
Kumar P, Gullberg U, Olsson I, Ajore R. Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1. PLoS ONE. 2015;10:e0123725 pubmed publisher
  • western blot; mouse; fig f6
Chung J, Bauer D, Ghamari A, Nizzi C, Deck K, Kingsley P, et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Sci Signal. 2015;8:ra34 pubmed publisher
  • western blot; rat; 1:4000
Zhang X, Liang D, Chi Z, Chu Q, Zhao C, Ma R, et al. Effect of zinc on high glucose-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells. Int J Mol Med. 2015;35:1747-54 pubmed publisher
  • western blot; human; 1:5000; fig 1g
Pardo F, Silva L, Sáez T, Salsoso R, Gutiérrez J, Sanhueza C, et al. Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction. Int J Obes (Lond). 2015;39:1264-73 pubmed publisher
  • western blot; human; fig 5
Simões A, Pereira D, Gomes S, Brito H, Carvalho T, French A, et al. Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-κB activation. Cell Death Dis. 2015;6:e1718 pubmed publisher
  • western blot; mouse
Amrutkar M, Cansby E, Chursa U, Nuñez Durán E, Chanclón B, Ståhlman M, et al. Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model. Diabetes. 2015;64:2791-804 pubmed publisher
  • western blot; human; fig 1
  • western blot; mouse; fig 1
Majumdar T, Chattopadhyay S, Ozhegov E, Dhar J, Goswami R, Sen G, et al. Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii. PLoS Pathog. 2015;11:e1004779 pubmed publisher
  • western blot; human; 1:1000
Seo H, Woo J, Shin Y, Ko S. Identification of biomarkers regulated by rexinoids (LGD1069, LG100268 and Ro25-7386) in human breast cells using Affymetrix microarray. Mol Med Rep. 2015;12:800-18 pubmed publisher
  • western blot; human; 1:3000; loading ...; fig 2
  • western blot; mouse; 1:3000; loading ...; fig 6
Yang Y, Deng Q, Feng X, Sun J. Use of the disulfiram/copper complex for breast cancer chemoprevention in MMTV-erbB2 transgenic mice. Mol Med Rep. 2015;12:746-52 pubmed publisher
  • western blot; human; fig 3
Yang L, Liu L, Xu Z, Liao W, Feng D, Dong X, et al. EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma. Oncotarget. 2015;6:5804-17 pubmed
  • western blot; human; fig 1
  • western blot; mouse; fig 1
Polletta L, Vernucci E, Carnevale I, Arcangeli T, Rotili D, Palmerio S, et al. SIRT5 regulation of ammonia-induced autophagy and mitophagy. Autophagy. 2015;11:253-70 pubmed publisher
  • western blot; human; 1:5000; fig 5
Lin S, Huang S, Kuo H, Chen C, Ma Y, Chu T, et al. Coral-derived compound WA-25 inhibits angiogenesis by attenuating the VEGF/VEGFR2 signaling pathway. Mar Drugs. 2015;13:861-78 pubmed publisher
  • western blot; mouse
Amrutkar M, Cansby E, Nuñez Durán E, Pirazzi C, Ståhlman M, Stenfeldt E, et al. Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH. FASEB J. 2015;29:1564-76 pubmed publisher
  • western blot; rat; fig 7
Xue T, Wei L, Zha D, Qiao L, Lu L, Chen F, et al. Exposure to acoustic stimuli promotes the development and differentiation of neural stem cells from the cochlear nuclei through the clusterin pathway. Int J Mol Med. 2015;35:637-44 pubmed publisher
  • western blot; human; 1:2000
Miyata M, Lee J, Susuki Miyata S, Wang W, Xu H, Kai H, et al. Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M. Nat Commun. 2015;6:6062 pubmed publisher
  • western blot; human; fig 4
Matsuda Y, Kobayashi Ishihara M, Fujikawa D, Ishida T, Watanabe T, Yamagishi M. Epigenetic heterogeneity in HIV-1 latency establishment. Sci Rep. 2015;5:7701 pubmed publisher
  • western blot; human; fig 1c
Chen J, Wang Z, Xu D, Liu Y, Gao Y. Aquaporin 3 promotes prostate cancer cell motility and invasion via extracellular signal-regulated kinase 1/2-mediated matrix metalloproteinase-3 secretion. Mol Med Rep. 2015;11:2882-8 pubmed publisher
  • western blot; human
Kim H, Li A, Ahn S, Song H, Zhang W. Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity. Sci Rep. 2014;4:7330 pubmed publisher
  • western blot; human; 1:1000
Lan N, Luo G, Yang X, Cheng Y, Zhang Y, Wang X, et al. 25-Hydroxyvitamin D3-deficiency enhances oxidative stress and corticosteroid resistance in severe asthma exacerbation. PLoS ONE. 2014;9:e111599 pubmed publisher
  • western blot; mouse
Bantikassegn A, Song X, Politi K. Isolation of epithelial, endothelial, and immune cells from lungs of transgenic mice with oncogene-induced lung adenocarcinomas. Am J Respir Cell Mol Biol. 2015;52:409-17 pubmed publisher
  • western blot; human
Dammer E, Lee A, Duong D, Gearing M, Lah J, Levey A, et al. Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins. Proteomics. 2015;15:508-519 pubmed publisher
  • western blot; human
Torsvik J, Johansson B, Dalva M, Marie M, Fjeld K, Johansson S, et al. Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction. J Biol Chem. 2014;289:29097-111 pubmed publisher
  • western blot; rat; 1:1000
Luo B, Li B, Wang W, Liu X, Xia Y, Zhang C, et al. NLRP3 gene silencing ameliorates diabetic cardiomyopathy in a type 2 diabetes rat model. PLoS ONE. 2014;9:e104771 pubmed publisher
  • western blot; mouse
Cansby E, Nerstedt A, Amrutkar M, Durán E, Smith U, Mahlapuu M. Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained. Mol Cell Endocrinol. 2014;393:143-51 pubmed publisher
  • western blot; human
Hu Q, Dong J, DU H, Zhang D, Ren H, Ma M, et al. Constitutive G?i coupling activity of very large G protein-coupled receptor 1 (VLGR1) and its regulation by PDZD7 protein. J Biol Chem. 2014;289:24215-25 pubmed publisher
  • western blot; human; 1:5000
Quintin J, Le Péron C, Palierne G, Bizot M, Cunha S, Sérandour A, et al. Dynamic estrogen receptor interactomes control estrogen-responsive trefoil Factor (TFF) locus cell-specific activities. Mol Cell Biol. 2014;34:2418-36 pubmed publisher
  • western blot; rat; 1:4000
Carloni S, Albertini M, Galluzzi L, Buonocore G, Proietti F, Balduini W. Increased autophagy reduces endoplasmic reticulum stress after neonatal hypoxia-ischemia: role of protein synthesis and autophagic pathways. Exp Neurol. 2014;255:103-12 pubmed publisher
  • western blot; mouse
Ohshima J, Lee Y, Sasai M, Saitoh T, Su Ma J, Kamiyama N, et al. Role of mouse and human autophagy proteins in IFN-?-induced cell-autonomous responses against Toxoplasma gondii. J Immunol. 2014;192:3328-35 pubmed publisher
  • western blot; human
Chandra S, Priyadarshini R, Madhavan V, Tikoo S, Hussain M, Mudgal R, et al. Enhancement of c-Myc degradation by BLM helicase leads to delayed tumor initiation. J Cell Sci. 2013;126:3782-95 pubmed publisher
  • western blot; human; 1:500
Pantaleo M, Astolfi A, Urbini M, Nannini M, Paterini P, Indio V, et al. Analysis of all subunits, SDHA, SDHB, SDHC, SDHD, of the succinate dehydrogenase complex in KIT/PDGFRA wild-type GIST. Eur J Hum Genet. 2014;22:32-9 pubmed publisher
  • western blot; human; fig 1
Xu J, Deng X, Tang M, Li L, Xiao L, Yang L, et al. Tyrosylprotein sulfotransferase-1 and tyrosine sulfation of chemokine receptor 4 are induced by Epstein-Barr virus encoded latent membrane protein 1 and associated with the metastatic potential of human nasopharyngeal carcinoma. PLoS ONE. 2013;8:e56114 pubmed publisher
  • western blot; human
Peddigari S, Li P, Rabe J, Martin S. hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition. Nucleic Acids Res. 2013;41:575-85 pubmed publisher
Cai W, Su L, Liao L, Liu Z, Langbein L, Dulaimi E, et al. PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth. Nat Commun. 2019;10:5800 pubmed publisher
Chernyshova K, Inoue K, Yamashita S, Fukuchi T, Kanki T. Glaucoma-Associated Mutations in the Optineurin Gene Have Limited Impact on Parkin-Dependent Mitophagy. Invest Ophthalmol Vis Sci. 2019;60:3625-3635 pubmed publisher
Wu H, Sun T, Bi R. Inhibition of insulin-like growth factor 1 signaling synergistically enhances the tumor suppressive role of triptolide in triple-negative breast cancer cells. Oncol Lett. 2019;18:822-829 pubmed publisher
Jayavaradhan R, Pillis D, Goodman M, Zhang F, Zhang Y, Andreassen P, et al. CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites. Nat Commun. 2019;10:2866 pubmed publisher
Islam M, Takano R, Yokochi T, Akter J, Nakamura Y, Nakagawara A, et al. Programmed expression of pro-apoptotic BMCC1 during apoptosis, triggered by DNA damage in neuroblastoma cells. BMC Cancer. 2019;19:542 pubmed publisher
Al Atrache Z, Lopez D, Hingley S, Appelt D. Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease. BMC Neurosci. 2019;20:6 pubmed publisher
Fenizia C, Bottino C, Corbetta S, Fittipaldi R, Floris P, Gaudenzi G, et al. SMYD3 promotes the epithelial-mesenchymal transition in breast cancer. Nucleic Acids Res. 2019;47:1278-1293 pubmed publisher
Carvajal G, Brukman N, Weigel Muñoz M, Battistone M, Guazzone V, Ikawa M, et al. Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4. Sci Rep. 2018;8:17531 pubmed publisher
Maffucci P, Chavez J, Jurkiw T, O Brien P, Abbott J, Reynolds P, et al. Biallelic mutations in DNA ligase 1 underlie a spectrum of immune deficiencies. J Clin Invest. 2018;128:5489-5504 pubmed publisher
Liao L, Liu Z, Langbein L, Cai W, Cho E, Na J, et al. Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer. elife. 2018;7: pubmed publisher
Lichvárová L, Henzi T, Safiulina D, Kaasik A, Schwaller B. Parvalbumin alters mitochondrial dynamics and affects cell morphology. Cell Mol Life Sci. 2018;75:4643-4666 pubmed publisher
Yang X, Liu H, Jiang X, Jin C, Xu Z, Li T, et al. Cyclooxygenase‑2‑mediated upregulation of heme oxygenase 1 mitigates the toxicity of deuterium‑tritium fusion radiation. Int J Mol Med. 2018;42:1945-1954 pubmed publisher
Wang H, Yao H, Yi B, Kazama K, Liu Y, Deshpande D, et al. MicroRNA-638 inhibits human airway smooth muscle cell proliferation and migration through targeting cyclin D1 and NOR1. J Cell Physiol. 2018;234:369-381 pubmed publisher
Li Y, Wu J, Yu X, Na S, Li K, Yang Z, et al. The Protective Role of Brain CYP2J in Parkinson's Disease Models. Oxid Med Cell Longev. 2018;2018:2917981 pubmed publisher
Wen H, Kumar V, Lan X, Shoshtari S, Eng J, Zhou X, et al. APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress. Biosci Rep. 2018;38: pubmed publisher
Yang J, Park K, Cho S. Inhibition of the CD36 receptor reduces visceral fat accumulation and improves insulin resistance in obese mice carrying the BDNF-Val66Met variant. J Biol Chem. 2018;293:13338-13348 pubmed publisher
Ricca C, Aillon A, Bergandi L, Alotto D, Castagnoli C, Silvagno F. Vitamin D Receptor Is Necessary for Mitochondrial Function and Cell Health. Int J Mol Sci. 2018;19: pubmed publisher
Fischietti M, Arslan A, Sassano A, Saleiro D, Majchrzak Kita B, Ebine K, et al. Slfn2 Regulates Type I Interferon Responses by Modulating the NF-κB Pathway. Mol Cell Biol. 2018;38: pubmed publisher
Gabbasov R, Xiao F, Howe C, Bickel L, O Brien S, Benrubi D, et al. NEDD9 promotes oncogenic signaling, a stem/mesenchymal gene signature, and aggressive ovarian cancer growth in mice. Oncogene. 2018;37:4854-4870 pubmed publisher
Ito F, Yoshimoto C, Yamada Y, Sudo T, Kobayashi H. The HNF-1β-USP28-Claspin pathway upregulates DNA damage-induced Chk1 activation in ovarian clear cell carcinoma. Oncotarget. 2018;9:17512-17522 pubmed publisher
Gu H, Do D, Liu X, Xu L, Su Y, Nah J, et al. The STAT3 Target Mettl8 Regulates Mouse ESC Differentiation via Inhibiting the JNK Pathway. Stem Cell Reports. 2018;10:1807-1820 pubmed publisher
Kuo W, Ho T, Chiang S, Pai P, Lin J, Lin D, et al. Rab9-dependent autophagy is required for the IGF-IIR triggering mitophagy to eliminate damaged mitochondria. J Cell Physiol. 2018;233:7080-7091 pubmed publisher
Gechijian L, Buckley D, Lawlor M, Reyes J, Paulk J, Ott C, et al. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands. Nat Chem Biol. 2018;14:405-412 pubmed publisher
Wu H, Liu H, Zuo F, Zhang L. Adenoviruses-mediated RNA interference targeting cytosolic phospholipase A2? attenuates focal ischemic brain damage in mice. Mol Med Rep. 2018;17:5601-5610 pubmed publisher
Siniscalco D, Trotta M, Brigida A, Maisto R, Luongo M, Ferraraccio F, et al. Intraperitoneal Administration of Oxygen/Ozone to Rats Reduces the Pancreatic Damage Induced by Streptozotocin. Biology (Basel). 2018;7: pubmed publisher
Sato Y, Watanabe S, Fukuda Y, Hashiguchi T, Yanagi Y, Ohno S. Cell-to-Cell Measles Virus Spread between Human Neurons Is Dependent on Hemagglutinin and Hyperfusogenic Fusion Protein. J Virol. 2018;92: pubmed publisher
Chen J, Kuo C, Pai P, Ho T, Chen T, Tsai F, et al. Mitochondrial ROS-induced ERK1/2 activation and HSF2-mediated AT1 R upregulation are required for doxorubicin-induced cardiotoxicity. J Cell Physiol. 2018;233:463-475 pubmed publisher
Wu X, Shi T, He Y, Wang F, Sang R, Ding J, et al. Methylation of transcription factor YY2 regulates its transcriptional activity and cell proliferation. Cell Discov. 2017;3:17035 pubmed publisher
Zhong Y, Yang J, Xu W, Wang Y, Zheng C, Li B, et al. KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition. Oncogene. 2017;36:6177-6189 pubmed publisher
Li Y, Zhang Y, Wang L, Wang P, Xue Y, Li X, et al. Autophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia. Autophagy. 2017;13:1145-1160 pubmed publisher
Jiang H, Wang W, Jiang X, Zeng W, Shen Z, Song Y, et al. ORF7 of Varicella-Zoster Virus Is Required for Viral Cytoplasmic Envelopment in Differentiated Neuronal Cells. J Virol. 2017;91: pubmed publisher
Panda D, Fernandez D, Lal M, Buehler E, Moss B. Triad of human cellular proteins, IRF2, FAM111A, and RFC3, restrict replication of orthopoxvirus SPI-1 host-range mutants. Proc Natl Acad Sci U S A. 2017;114:3720-3725 pubmed publisher
Motiani K, Savolainen A, Eskelinen J, Toivanen J, Ishizu T, Yli Karjanmaa M, et al. Two weeks of moderate-intensity continuous training, but not high-intensity interval training, increases insulin-stimulated intestinal glucose uptake. J Appl Physiol (1985). 2017;122:1188-1197 pubmed publisher
Schober T, Magg T, Laschinger M, Rohlfs M, Linhares N, Puchalka J, et al. A human immunodeficiency syndrome caused by mutations in CARMIL2. Nat Commun. 2017;8:14209 pubmed publisher
Zhang T, Zhou Y, Li L, Wang Z, Shen W, Schatten H, et al. CenpH regulates meiotic G2/M transition by modulating the APC/CCdh1-cyclin B1 pathway in oocytes. Development. 2017;144:305-312 pubmed publisher
Zhang N, Lu C, Chen L. miR-217 regulates tumor growth and apoptosis by targeting the MAPK signaling pathway in colorectal cancer. Oncol Lett. 2016;12:4589-4597 pubmed publisher
Kuo W, Lo J, Ho T, Pai P, Chiang S, Chen P, et al. Doxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death. Cell Death Dis. 2016;7:e2455 pubmed publisher
Chen H, Yu H, Tarn W. DDX3 Modulates Neurite Development via Translationally Activating an RNA Regulon Involved in Rac1 Activation. J Neurosci. 2016;36:9792-804 pubmed publisher
Wang Y, Wang H, Pan T, Li L, Li J, Yang H. Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of non-small cell lung cancer cells. Oncotarget. 2016;7:64360-64370 pubmed publisher
Devkota S, Jeong H, Kim Y, Ali M, Roh J, Hwang D, et al. Functional characterization of EI24-induced autophagy in the degradation of RING-domain E3 ligases. Autophagy. 2016;12:2038-2053 pubmed
Zhang H, Alshareef A, Wu C, Jiao J, Sorensen P, Lai R, et al. miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma. Carcinogenesis. 2016;37:858-869 pubmed publisher
Shao L, Huang L, Yan S, Jin J, Ren S. Cordycepin induces apoptosis in human liver cancer HepG2 cells through extrinsic and intrinsic signaling pathways. Oncol Lett. 2016;12:995-1000 pubmed
Jin M, Chen Y, Zhou Y, Mei Y, Liu W, Pan C, et al. Transplantation of bone marrow-derived mesenchymal stem cells expressing elastin alleviates pelvic floor dysfunction. Stem Cell Res Ther. 2016;7:51 pubmed publisher
Jiang C, Zhou Z, Quan Y, Zhang S, Wang T, Zhao X, et al. CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection. Cell Rep. 2016;14:2389-401 pubmed publisher
Su B, Su J, Zeng Y, Liu F, Xia H, Ma Y, et al. Diallyl disulfide suppresses epithelial-mesenchymal transition, invasion and proliferation by downregulation of LIMK1 in gastric cancer. Oncotarget. 2016;7:10498-512 pubmed publisher
Lin C, Wang C, Hsu S, Liao L, Lin T, Hsueh C. Molecular Mechanisms Responsible for Neuron-Derived Conditioned Medium (NCM)-Mediated Protection of Ischemic Brain. PLoS ONE. 2016;11:e0146692 pubmed publisher
Zheng X, Dai W, Chen X, Wang K, Zhang W, Liu L, et al. Caffeine reduces hepatic lipid accumulation through regulation of lipogenesis and ER stress in zebrafish larvae. J Biomed Sci. 2015;22:105 pubmed publisher
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product information
Product Name :
Actin (C-2) Antibody
Gene Name :
ACTG1, ACTC1, ACTA1, ACTA2, ACTG2, ACTB
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-8432
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Actin
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM, ELISA
Epitope :
C-terminal (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA