Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; 1:500; fig 4
| Jing W, Zhang X, Sun W, Hou X, Yao Z, Zhu Y. CRISPR/CAS9-Mediated Genome Editing of miRNA-155 Inhibits Proinflammatory Cytokine Production by RAW264.7 Cells. Biomed Res Int. 2015;2015:326042 pubmed publisher
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| Chen Z, Shojaee S, Buchner M, Geng H, Lee J, Klemm L, et al. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2015;521:357-61 pubmed publisher
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- western blot; human; fig 2
| Nakahata S, Ichikawa T, Maneesaay P, Saito Y, Nagai K, Tamura T, et al. Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers. Nat Commun. 2014;5:3393 pubmed publisher
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| Albrecht V, Hofer T, Foxwell B, Frankenberger M, Ziegler Heitbrock L. Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. BMC Immunol. 2008;9:69 pubmed publisher
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| Nunes de Miranda S, Wilhelm T, Huber M, Zorn C. Differential Lyn-dependence of the SHIP1-deficient mast cell phenotype. Cell Commun Signal. 2016;14:12 pubmed publisher
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| Freedman T, Tan Y, Skrzypczynska K, Manz B, Sjaastad F, Goodridge H, et al. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. elife. 2015;4: pubmed publisher
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| Ní Gabhann J, Hams E, Smith S, Wynne C, Byrne J, Brennan K, et al. Btk regulates macrophage polarization in response to lipopolysaccharide. PLoS ONE. 2014;9:e85834 pubmed publisher
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| Li Y, Zhang P, Wang C, Han C, Meng J, Liu X, et al. Immune responsive gene 1 (IRG1) promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species. J Biol Chem. 2013;288:16225-34 pubmed publisher
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| Brauer H, Strauss J, Wegner W, Muller Tidow C, Horstmann M, Jücker M. Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling. Cell Signal. 2012;24:2095-101 pubmed publisher
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| Vartanian K, Stevens S, Marsh B, Williams Karnesky R, Lessov N, Stenzel Poore M. LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury. J Neuroinflammation. 2011;8:140 pubmed publisher
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| Nalaskowski M, Metzner A, Brehm M, Labiadh S, Brauer H, Grabinski N, et al. The inositol 5-phosphatase SHIP1 is a nucleo-cytoplasmic shuttling protein and enzymatically active in cell nuclei. Cell Signal. 2012;24:621-8 pubmed publisher
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| Hou S, Pauls S, Liu P, Marshall A. The PH domain adaptor protein Bam32/DAPP1 functions in mast cells to restrain Fc?RI-induced calcium flux and granule release. Mol Immunol. 2010;48:89-97 pubmed publisher
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| Zhang J, Ravichandran K, Garrison J. A key role for the phosphorylation of Ser440 by the cyclic AMP-dependent protein kinase in regulating the activity of the Src homology 2 domain-containing Inositol 5'-phosphatase (SHIP1). J Biol Chem. 2010;285:34839-49 pubmed publisher
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| Levin V, Panchabhai S, Shen L, Kornblau S, Qiu Y, Baggerly K. Different changes in protein and phosphoprotein levels result from serum starvation of high-grade glioma and adenocarcinoma cell lines. J Proteome Res. 2010;9:179-91 pubmed publisher
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| Mihrshahi R, Barclay A, Brown M. Essential roles for Dok2 and RasGAP in CD200 receptor-mediated regulation of human myeloid cells. J Immunol. 2009;183:4879-86 pubmed publisher
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| Ara T, Kurata K, Hirai K, Uchihashi T, Uematsu T, Imamura Y, et al. Human gingival fibroblasts are critical in sustaining inflammation in periodontal disease. J Periodontal Res. 2009;44:21-7 pubmed publisher
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| Lo T, Barnhill L, Kim Y, Nakae E, Yu A, Diccianni M. Inactivation of SHIP1 in T-cell acute lymphoblastic leukemia due to mutation and extensive alternative splicing. Leuk Res. 2009;33:1562-6 pubmed publisher
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| Marois L, Vaillancourt M, Marois S, Proulx S, Pare G, Rollet Labelle E, et al. The ubiquitin ligase c-Cbl down-regulates FcgammaRIIa activation in human neutrophils. J Immunol. 2009;182:2374-84 pubmed publisher
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| Sly L, Hamilton M, Kuroda E, Ho V, Antignano F, Omeis S, et al. SHIP prevents lipopolysaccharide from triggering an antiviral response in mice. Blood. 2009;113:2945-54 pubmed publisher
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| Bishop J, Sly L, Krystal G, Finlay B. The inositol phosphatase SHIP controls Salmonella enterica serovar Typhimurium infection in vivo. Infect Immun. 2008;76:2913-22 pubmed publisher
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| Tessmer M, Fugere C, Stevenaert F, Naidenko O, Chong H, Leclercq G, et al. KLRG1 binds cadherins and preferentially associates with SHIP-1. Int Immunol. 2007;19:391-400 pubmed
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| Dong S, Corre B, Foulon E, Dufour E, Veillette A, Acuto O, et al. T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2. J Exp Med. 2006;203:2509-18 pubmed
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| Vaillancourt M, Levasseur S, Tremblay M, Marois L, Rollet Labelle E, Naccache P. The Src homology 2-containing inositol 5-phosphatase 1 (SHIP1) is involved in CD32a signaling in human neutrophils. Cell Signal. 2006;18:2022-32 pubmed
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| Yogo K, Mizutamari M, Mishima K, Takenouchi H, Ishida Kitagawa N, Sasaki T, et al. Src homology 2 (SH2)-containing 5'-inositol phosphatase localizes to podosomes, and the SH2 domain is implicated in the attenuation of bone resorption in osteoclasts. Endocrinology. 2006;147:3307-17 pubmed
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| Wain C, Westwick J, Ward S. Heterologous regulation of chemokine receptor signaling by the lipid phosphatase SHIP in lymphocytes. Cell Signal. 2005;17:1194-202 pubmed
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| Vanderwinden J, Wang D, Paternotte N, Mignon S, Isozaki K, Erneux C. Differences in signaling pathways and expression level of the phosphoinositide phosphatase SHIP1 between two oncogenic mutants of the receptor tyrosine kinase KIT. Cell Signal. 2006;18:661-9 pubmed
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| Nakamura K, Kouro T, Kincade P, Malykhin A, Maeda K, Coggeshall K. Src homology 2-containing 5-inositol phosphatase (SHIP) suppresses an early stage of lymphoid cell development through elevated interleukin-6 production by myeloid cells in bone marrow. J Exp Med. 2004;199:243-54 pubmed
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