product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
p-p70 S6 kinase alpha (A-6) Antibody
catalog :
sc-8416
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
A-6
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 4
Han Y, Lee J, Lee S. Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways. Mol Med Rep. 2015;12:3446-3452 pubmed publisher
  • western blot; rat; 1:500
Salvatierra C, Reis S, Pessoa A, De Souza L, Stoppiglia L, Veloso R, et al. Short-term low-protein diet during pregnancy alters islet area and protein content of phosphatidylinositol 3-kinase pathway in rats. An Acad Bras Cienc. 2015;87:1007-18 pubmed publisher
  • immunocytochemistry; human
Gargalionis A, Korkolopoulou P, Farmaki E, Piperi C, Dalagiorgou G, Adamopoulos C, et al. Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer. Int J Cancer. 2015;136:1515-27 pubmed publisher
Kim S, Lam T, Yook J, Ahn S. Antioxidant modifications induced by the new metformin derivative HL156A regulate metabolic reprogramming in SAMP1/kl (-/-) mice. Aging (Albany NY). 2018;10:2338-2355 pubmed publisher
Liu P, Zhang M, Niu Q, Zhang F, Yang Y, Jiang X. Knockdown of long non-coding RNA ANRIL inhibits tumorigenesis in human gastric cancer cells via microRNA-99a-mediated down-regulation of BMI1. Braz J Med Biol Res. 2018;51:e6839 pubmed publisher
Leal P, Garcia P, Sandoval A, Buchegger K, Weber H, Tapia O, et al. AKT/mTOR substrate P70S6K is frequently phosphorylated in gallbladder cancer tissue and cell lines. Onco Targets Ther. 2013;6:1373-84 pubmed publisher
Tang Q, Li G, Wei X, Zhang J, Chiu J, Hasenmayer D, et al. Resveratrol-induced apoptosis is enhanced by inhibition of autophagy in esophageal squamous cell carcinoma. Cancer Lett. 2013;336:325-37 pubmed publisher
Tan W, Jia W, Sun V, Mihm M, Nelson J. Topical rapamycin suppresses the angiogenesis pathways induced by pulsed dye laser: molecular mechanisms of inhibition of regeneration and revascularization of photocoagulated cutaneous blood vessels. Lasers Surg Med. 2012;44:796-804 pubmed publisher
Wehenkel M, Ban J, Ho Y, Carmony K, Hong J, Kim K. A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice. Br J Cancer. 2012;107:53-62 pubmed publisher
Greer A, Hearing P, Ketner G. The adenovirus E4 11 k protein binds and relocalizes the cytoplasmic P-body component Ddx6 to aggresomes. Virology. 2011;417:161-8 pubmed publisher
Ozgur S, Chekulaeva M, Stoecklin G. Human Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies. Mol Cell Biol. 2010;30:4308-23 pubmed publisher
Unterstab G, Gosert R, Leuenberger D, Lorentz P, Rinaldo C, Hirsch H. The polyomavirus BK agnoprotein co-localizes with lipid droplets. Virology. 2010;399:322-31 pubmed publisher
Abdeen A, Chou A, Healey J, Khanna C, Osborne T, Hewitt S, et al. Correlation between clinical outcome and growth factor pathway expression in osteogenic sarcoma. Cancer. 2009;115:5243-50 pubmed publisher
Wittmann S, Daniel C, Braun A, Vogelbacher R, Shimizu F, Kawachi H, et al. The mTOR inhibitor everolimus attenuates the time course of chronic anti-Thy1 nephritis in the rat. Nephron Exp Nephrol. 2008;108:e45-56 pubmed publisher
Keller K, Daniel C, Schocklmann H, Endlich K, Kerjaschki D, Johnson R, et al. Everolimus inhibits glomerular endothelial cell proliferation and VEGF, but not long-term recovery in experimental thrombotic microangiopathy. Nephrol Dial Transplant. 2006;21:2724-35 pubmed
product information
Product Name :
p-p70 S6 kinase alpha (A-6) Antibody
Gene Name :
RPS6KB1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-8416
Modification :
phosporylated
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
p-p70 S6 kinase alpha
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
Ser 411 (r)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA