product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
p-Elk-1 (B-4) Antibody
catalog :
sc-8406
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
B-4
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 5b
Lu J, Liu L, Zheng M, Li X, Wu A, Wu Q, et al. MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function. Oncogene. 2018;37:3864-3878 pubmed publisher
  • western blot; human; loading ...; fig 10a
Wu J, Xiang S, Zhang M, Fang B, Huang H, Kwon O, et al. Histone deacetylase 6 (HDAC6) deacetylates extracellular signal-regulated kinase 1 (ERK1) and thereby stimulates ERK1 activity. J Biol Chem. 2018;293:1976-1993 pubmed publisher
Donnio L, Bidon B, Hashimoto S, May M, Epanchintsev A, Ryan C, et al. MED12-related XLID disorders are dose-dependent of immediate early genes (IEGs) expression. Hum Mol Genet. 2017;26:2062-2075 pubmed publisher
Kim S, Kang H, Han J, Park S. The transcription factor Sp1 is responsible for aging-dependent altered nucleocytoplasmic trafficking. Aging Cell. 2012;11:1102-9 pubmed publisher
Parikh N, Shuck R, Nguyen T, Herron A, Donehower L. Mouse tissues that undergo neoplastic progression after K-Ras activation are distinguished by nuclear translocation of phospho-Erk1/2 and robust tumor suppressor responses. Mol Cancer Res. 2012;10:845-55 pubmed publisher
Schneider A, Mehmood T, Pannetier S, Hanauer A. Altered ERK/MAPK signaling in the hippocampus of the mrsk2_KO mouse model of Coffin-Lowry syndrome. J Neurochem. 2011;119:447-59 pubmed publisher
Li L, Boddul S, Patil S, Zheng J, An G, Hoger H, et al. Proteins linked to extinction in contextual fear conditioning in the C57BL/6J mouse. Proteomics. 2011;11:3706-24 pubmed publisher
Kim S, Kang H, Choi H, Park S. Reduction of Nup107 attenuates the growth factor signaling in the senescent cells. Biochem Biophys Res Commun. 2010;401:131-6 pubmed publisher
Shukla A, Jain M, Chauhan S. Ets-1/Elk-1 is a critical mediator of dipeptidyl-peptidase III transcription in human glioblastoma cells. FEBS J. 2010;277:1861-75 pubmed publisher
Mahmoodzadeh S, Dworatzek E, Fritschka S, Pham T, Regitz Zagrosek V. 17beta-Estradiol inhibits matrix metalloproteinase-2 transcription via MAP kinase in fibroblasts. Cardiovasc Res. 2010;85:719-28 pubmed publisher
Hong S, Jeon Y, Lee H, Kim J, Baek J, Lee J. Activation of RhoA and FAK induces ERK-mediated osteopontin expression in mechanical force-subjected periodontal ligament fibroblasts. Mol Cell Biochem. 2010;335:263-72 pubmed publisher
Rössler O, Thiel G. Thrombin induces Egr-1 expression in fibroblasts involving elevation of the intracellular Ca2+ concentration, phosphorylation of ERK and activation of ternary complex factor. BMC Mol Biol. 2009;10:40 pubmed publisher
Mayer S, Willars G, Nishida E, Thiel G. Elk-1, CREB, and MKP-1 regulate Egr-1 expression in gonadotropin-releasing hormone stimulated gonadotrophs. J Cell Biochem. 2008;105:1267-78 pubmed publisher
Adiseshaiah P, Li J, Vaz M, Kalvakolanu D, Reddy S. ERK signaling regulates tumor promoter induced c-Jun recruitment at the Fra-1 promoter. Biochem Biophys Res Commun. 2008;371:304-8 pubmed publisher
Sermeus A, Cosse J, Crespin M, Mainfroid V, de Longueville F, Ninane N, et al. Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity. Mol Cancer. 2008;7:27 pubmed publisher
Hsieh H, Wu C, Yang C. Bradykinin induces matrix metalloproteinase-9 expression and cell migration through a PKC-delta-dependent ERK/Elk-1 pathway in astrocytes. Glia. 2008;56:619-32 pubmed publisher
Rössler O, Henss I, Thiel G. Transcriptional response to muscarinic acetylcholine receptor stimulation: regulation of Egr-1 biosynthesis by ERK, Elk-1, MKP-1, and calcineurin in carbachol-stimulated human neuroblastoma cells. Arch Biochem Biophys. 2008;470:93-102 pubmed
Lefloch R, Pouyssegur J, Lenormand P. Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels. Mol Cell Biol. 2008;28:511-27 pubmed
Stefano L, Rössler O, Griesemer D, Hoth M, Thiel G. P2X(7) receptor stimulation upregulates Egr-1 biosynthesis involving a cytosolic Ca(2+) rise, transactivation of the EGF receptor and phosphorylation of ERK and Elk-1. J Cell Physiol. 2007;213:36-44 pubmed
Adiseshaiah P, Kalvakolanu D, Reddy S. A JNK-independent signaling pathway regulates TNF alpha-stimulated, c-Jun-driven FRA-1 protooncogene transcription in pulmonary epithelial cells. J Immunol. 2006;177:7193-202 pubmed
Nandiwada S, Li W, Zhang R, Mueller D. p300/Cyclic AMP-responsive element binding-binding protein mediates transcriptional coactivation by the CD28 T cell costimulatory receptor. J Immunol. 2006;177:401-13 pubmed
Zhang Q, Adiseshaiah P, Kalvakolanu D, Reddy S. A Phosphatidylinositol 3-kinase-regulated Akt-independent signaling promotes cigarette smoke-induced FRA-1 expression. J Biol Chem. 2006;281:10174-81 pubmed
product information
Product Name :
p-Elk-1 (B-4) Antibody
Gene Name :
ELK1
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-8406
Modification :
phosporylated
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
p-Elk-1
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
Ser 383 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA