product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Pax-6 (PAX6) Antibody
catalog :
sc-81649
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PAX6
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 63
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 1c
  • western blot; human; loading ...; fig 1f, 4g
Zhang Y, He L, Huang L, Yao S, Lin N, Li P, et al. Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2-Hippo signaling pathway. Clin Transl Med. 2021;11:e503 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig s2-1a
Yoshida S, Aoki K, Fujiwara K, Nakakura T, Kawamura A, Yamada K, et al. The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis. elife. 2020;9: pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 5
Fang J, Shaw P, Wang Y, Goldberg J. Krüppel-Like Factor 4 (KLF4) Is Not Required for Retinal Cell Differentiation. Eneuro. 2016;3: pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 4
  • western blot; human; fig 4
Grandy R, Whitfield T, Wu H, Fitzgerald M, VanOudenhove J, Zaidi S, et al. Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation. Mol Cell Biol. 2016;36:615-27 pubmed publisher
del Toro D, Ruff T, Cederfjäll E, Villalba A, Seyit Bremer G, Borrell V, et al. Regulation of Cerebral Cortex Folding by Controlling Neuronal Migration via FLRT Adhesion Molecules. Cell. 2017;169:621-635.e16 pubmed publisher
Zieba J, Miller A, Gordiienko O, Smith G, Krynska B. Clusters of amniotic fluid cells and their associated early neuroepithelial markers in experimental myelomeningocele: Correlation with astrogliosis. PLoS ONE. 2017;12:e0174625 pubmed publisher
Miyashita H, Niwano H, Yoshida S, Hatou S, Inagaki E, Tsubota K, et al. Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model. Sci Rep. 2017;7:43557 pubmed publisher
Sartore R, Cardoso S, Lages Y, Paraguassu J, Stelling M, Madeiro da Costa R, et al. Trace elements during primordial plexiform network formation in human cerebral organoids. Peerj. 2017;5:e2927 pubmed publisher
Subramanian L, Bershteyn M, Paredes M, Kriegstein A. Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun. 2017;8:14167 pubmed publisher
Middelkamp S, van Heesch S, Braat A, de Ligt J, van Iterson M, Simonis M, et al. Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells. Genome Med. 2017;9:9 pubmed publisher
Lin H, Li Q, Lei Y. An Integrated Miniature Bioprocessing for Personalized Human Induced Pluripotent Stem Cell Expansion and Differentiation into Neural Stem Cells. Sci Rep. 2017;7:40191 pubmed publisher
Zhao J, Afshari N. Generation of Human Corneal Endothelial Cells via In Vitro Ocular Lineage Restriction of Pluripotent Stem Cells. Invest Ophthalmol Vis Sci. 2016;57:6878-6884 pubmed publisher
Foerster P, Daclin M, Asm S, Faucourt M, Boletta A, Genovesio A, et al. mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis. Development. 2017;144:201-210 pubmed publisher
Yao K, Qiu S, Tian L, Snider W, Flannery J, Schaffer D, et al. Wnt Regulates Proliferation and Neurogenic Potential of Müller Glial Cells via a Lin28/let-7 miRNA-Dependent Pathway in Adult Mammalian Retinas. Cell Rep. 2016;17:165-178 pubmed publisher
Borgs L, Peyre E, Alix P, Hanon K, Grobarczyk B, Godin J, et al. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Sci Rep. 2016;6:33377 pubmed publisher
Fujiwara N, Cave J. Partial Conservation between Mice and Humans in Olfactory Bulb Interneuron Transcription Factor Codes. Front Neurosci. 2016;10:337 pubmed publisher
Takeo Y, Kurabayashi N, Nguyen M, Sanada K. The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway. Sci Rep. 2016;6:25180 pubmed publisher
Otani T, Marchetto M, Gage F, Simons B, Livesey F. 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size. Cell Stem Cell. 2016;18:467-80 pubmed publisher
Wang W, Jossin Y, Chai G, Lien W, Tissir F, Goffinet A. Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016;7:10936 pubmed publisher
Ahmad Z, Rafeeq M, Collombat P, Mansouri A. Pax6 Inactivation in the Adult Pancreas Reveals Ghrelin as Endocrine Cell Maturation Marker. PLoS ONE. 2015;10:e0144597 pubmed publisher
Thomsen E, Mich J, Yao Z, Hodge R, Doyle A, Jang S, et al. Fixed single-cell transcriptomic characterization of human radial glial diversity. Nat Methods. 2016;13:87-93 pubmed publisher
Fernández Santiago R, Carballo Carbajal I, Castellano G, Torrent R, Richaud Y, Sánchez Danés A, et al. Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients. EMBO Mol Med. 2015;7:1529-46 pubmed publisher
Straccia M, Garcia Díaz Barriga G, Sanders P, Bombau G, Carrere J, Mairal P, et al. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Mol Ther Methods Clin Dev. 2015;2:15030 pubmed publisher
Zindy F, Lee Y, Kawauchi D, Ayrault O, Merzoug L, Li Y, et al. Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation. PLoS ONE. 2015;10:e0129642 pubmed publisher
Roybon L, Mastracci T, Li J, Stott S, Leiter A, Sussel L, et al. The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1. PLoS ONE. 2015;10:e0128035 pubmed publisher
Mils V, Bosch S, Roy J, Bel Vialar S, Belenguer P, Pituello F, et al. Mitochondrial reshaping accompanies neural differentiation in the developing spinal cord. PLoS ONE. 2015;10:e0128130 pubmed publisher
Chen Q, Arai D, Kawakami K, Sawada T, Jing X, Miyajima M, et al. EphA4 Regulates the Balance between Self-Renewal and Differentiation of Radial Glial Cells and Intermediate Neuronal Precursors in Cooperation with FGF Signaling. PLoS ONE. 2015;10:e0126942 pubmed publisher
Jin K, Jiang H, Xiao D, Zou M, Zhu J, Xiang M. Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis. Mol Brain. 2015;8:28 pubmed publisher
Karbalaie K, Tanhaei S, Rabiei F, Kiani Esfahani A, Masoudi N, Nasr Esfahani M, et al. Stem cells from human exfoliated deciduous tooth exhibit stromal-derived inducing activity and lead to generation of neural crest cells from human embryonic stem cells. Cell J. 2015;17:37-48 pubmed
Greenman R, Gorelik A, Sapir T, Baumgart J, Zamor V, Segal Salto M, et al. Non-cell autonomous and non-catalytic activities of ATX in the developing brain. Front Neurosci. 2015;9:53 pubmed publisher
Wilson P, Payne T. Genetic reprogramming of human amniotic cells with episomal vectors: neural rosettes as sentinels in candidate selection for validation assays. Peerj. 2014;2:e668 pubmed publisher
Goggolidou P, Stevens J, Agueci F, Keynton J, Wheway G, Grimes D, et al. ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis. Development. 2014;141:3966-77 pubmed publisher
Yan X, Sabrautzki S, Horsch M, Fuchs H, Gailus Durner V, Beckers J, et al. Peroxidasin is essential for eye development in the mouse. Hum Mol Genet. 2014;23:5597-614 pubmed publisher
Raviv S, Bharti K, Rencus Lazar S, Cohen Tayar Y, Schyr R, Evantal N, et al. PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF. PLoS Genet. 2014;10:e1004360 pubmed publisher
Shahi M, Holt R, Rebhun R. Blocking signaling at the level of GLI regulates downstream gene expression and inhibits proliferation of canine osteosarcoma cells. PLoS ONE. 2014;9:e96593 pubmed publisher
Nemati S, Jabbari R, Hajinasrollah M, Zare Mehrjerdi N, Azizi H, Hemmesi K, et al. Transplantation of adult monkey neural stem cells into a contusion spinal cord injury model in rhesus macaque monkeys. Cell J. 2014;16:117-130 pubmed
Hui S, Sengupta D, Lee S, Sen T, Kundu S, Mathavan S, et al. Genome wide expression profiling during spinal cord regeneration identifies comprehensive cellular responses in zebrafish. PLoS ONE. 2014;9:e84212 pubmed publisher
Li Y, Hao H, Tzatzalos E, Lin R, Doh S, Liu L, et al. Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells. Biol Open. 2014;3:172-84 pubmed publisher
Saghizadeh M, Winkler M, Kramerov A, Hemmati D, Ghiam C, Dimitrijevich S, et al. A simple alkaline method for decellularizing human amniotic membrane for cell culture. PLoS ONE. 2013;8:e79632 pubmed publisher
Li P, Chen Y, Mak K, Wong C, Wang C, Yuan P. Functional role of Mst1/Mst2 in embryonic stem cell differentiation. PLoS ONE. 2013;8:e79867 pubmed publisher
Paschaki M, Cammas L, Muta Y, Matsuoka Y, Mak S, Rataj Baniowska M, et al. Retinoic acid regulates olfactory progenitor cell fate and differentiation. Neural Dev. 2013;8:13 pubmed publisher
Shaham O, Gueta K, Mor E, Oren Giladi P, Grinberg D, Xie Q, et al. Pax6 regulates gene expression in the vertebrate lens through miR-204. PLoS Genet. 2013;9:e1003357 pubmed publisher
Wang Y, Liu J, Liu C, Naji A, Stoffers D. MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic ?-cells. Diabetes. 2013;62:887-95 pubmed publisher
Hunter C, Dixit S, Cohen T, Ediger B, Wilcox C, Ferreira M, et al. Islet ?-, ?-, and ?-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor. Diabetes. 2013;62:875-86 pubmed publisher
Law K, Makino S, Mo R, Zhang X, Puviindran V, Hui C. Antagonistic and cooperative actions of Kif7 and Sufu define graded intracellular Gli activities in Hedgehog signaling. PLoS ONE. 2012;7:e50193 pubmed publisher
Konno D, Iwashita M, Satoh Y, Momiyama A, Abe T, Kiyonari H, et al. The mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortex. PLoS ONE. 2012;7:e46577 pubmed publisher
Shubham K, Mishra R. Pax6 interacts with SPARC and TGF-? in murine eyes. Mol Vis. 2012;18:951-6 pubmed
Kiselev Y, Eriksen T, Forsdahl S, Nguyen L, Mikkola I. 3T3 cell lines stably expressing Pax6 or Pax6(5a)--a new tool used for identification of common and isoform specific target genes. PLoS ONE. 2012;7:e31915 pubmed publisher
Sebastián Serrano A, Sandonìs A, Cardozo M, Rodríguez Tornos F, Bovolenta P, Nieto M. P?x6 expression in postmitotic neurons mediates the growth of axons in response to SFRP1. PLoS ONE. 2012;7:e31590 pubmed publisher
Yoshida S, Yasuda M, Miyashita H, Ogawa Y, Yoshida T, Matsuzaki Y, et al. Generation of stratified squamous epithelial progenitor cells from mouse induced pluripotent stem cells. PLoS ONE. 2011;6:e28856 pubmed publisher
Chang H, Lin D, Chen Y, Liu H, Lin W, Tsao Z, et al. Intravitreal homocysteine-thiolactone injection leads to the degeneration of multiple retinal cells, including photoreceptors. Mol Vis. 2011;17:1946-56 pubmed
Gao J, Wang J, Wang Y, Dai W, Lu L. Regulation of Pax6 by CTCF during induction of mouse ES cell differentiation. PLoS ONE. 2011;6:e20954 pubmed publisher
Wang X, Tsai J, Lamonica B, Kriegstein A. A new subtype of progenitor cell in the mouse embryonic neocortex. Nat Neurosci. 2011;14:555-61 pubmed publisher
Ishizuka K, Kamiya A, Oh E, Kanki H, Seshadri S, Robinson J, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature. 2011;473:92-6 pubmed publisher
Matsuoka R, Nguyen Ba Charvet K, Parray A, Badea T, Chedotal A, Kolodkin A. Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina. Nature. 2011;470:259-63 pubmed publisher
London A, Itskovich E, Benhar I, Kalchenko V, Mack M, Jung S, et al. Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages. J Exp Med. 2011;208:23-39 pubmed publisher
Meier Stiegen F, Schwanbeck R, Bernoth K, Martini S, Hieronymus T, Ruau D, et al. Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitors. PLoS ONE. 2010;5:e11481 pubmed publisher
Silver D, Watkins Chow D, Schreck K, Pierfelice T, Larson D, Burnetti A, et al. The exon junction complex component Magoh controls brain size by regulating neural stem cell division. Nat Neurosci. 2010;13:551-8 pubmed publisher
Sakurai K, Shimoji M, Tahimic C, Aiba K, Kawase E, Hasegawa K, et al. Efficient integration of transgenes into a defined locus in human embryonic stem cells. Nucleic Acids Res. 2010;38:e96 pubmed publisher
Vogel T, Ahrens S, Büttner N, Krieglstein K. Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component. Cereb Cortex. 2010;20:661-71 pubmed publisher
Das G, Choi Y, Sicinski P, Levine E. Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells. Neural Dev. 2009;4:15 pubmed publisher
Shechter R, Ronen A, Rolls A, London A, Bakalash S, Young M, et al. Toll-like receptor 4 restricts retinal progenitor cell proliferation. J Cell Biol. 2008;183:393-400 pubmed publisher
Campbell C, Piper M, Plachez C, Yeh Y, Baizer J, Osinski J, et al. The transcription factor Nfix is essential for normal brain development. BMC Dev Biol. 2008;8:52 pubmed publisher
product information
Catalog Number :
sc-81649
Product Name :
Pax-6 (PAX6) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
PAX6
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Pax-6
Specificity :
mouse, rat, human, avian
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA