product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
HDAC2 (3F3) Antibody
catalog :
sc-81599
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3F3
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 14
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human; loading ...; fig 4a
Li J, Jin C, Sun L, Wang B, Hua P, Zhang Y. HDAC2 enhances esophageal squamous cell carcinoma development through down-regulating microRNA-503-5p and promoting CXCL10. Clin Epigenetics. 2021;13:96 pubmed publisher
  • western blot; human; fig 7c
Patel N, Wang J, Shiozawa K, Jones K, Zhang Y, Prokop J, et al. HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression. iScience. 2019;13:43-54 pubmed publisher
  • western blot; mouse; 1:500
Tyler C, Hafez A, Solomon E, Allan A. Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. Toxicol Appl Pharmacol. 2015;288:40-51 pubmed publisher
  • western blot; human; 1:1000; fig 2
Ecker J, Oehme I, Mazitschek R, Korshunov A, Kool M, Hielscher T, et al. Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma. Acta Neuropathol Commun. 2015;3:22 pubmed publisher
Lee J, Kang H. Nucleolin Regulates Pulmonary Artery Smooth Muscle Cell Proliferation under Hypoxia by Modulating miRNA Expression. Cells. 2023;12: pubmed publisher
Snijders Blok L, Hiatt S, Bowling K, Prokop J, Engel K, Cochran J, et al. De novo mutations in MED13, a component of the Mediator complex, are associated with a novel neurodevelopmental disorder. Hum Genet. 2018;137:375-388 pubmed publisher
Mao Q, Zhang W, Zhao K, Cao B, Yuan H, Wei L, et al. MicroRNA-455 suppresses the oncogenic function of HDAC2 in human colorectal cancer. Braz J Med Biol Res. 2017;50:e6103 pubmed publisher
Hagelkruys A, Mattes K, Moos V, Rennmayr M, Ringbauer M, Sawicka A, et al. Essential Nonredundant Function of the Catalytic Activity of Histone Deacetylase 2 in Mouse Development. Mol Cell Biol. 2016;36:462-74 pubmed publisher
Hagelkruys A, Lagger S, Krahmer J, Leopoldi A, Artaker M, Pusch O, et al. A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. Development. 2014;141:604-616 pubmed publisher
Holownia A, Mroz R, Wielgat P, Jakubow P, Jablonski J, Sulek J, et al. Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1. Naunyn Schmiedebergs Arch Pharmacol. 2014;387:271-80 pubmed publisher
Kinnaird J, Weir W, Durrani Z, Pillai S, Baird M, Shiels B. A Bovine Lymphosarcoma Cell Line Infected with Theileria annulata Exhibits an Irreversible Reconfiguration of Host Cell Gene Expression. PLoS ONE. 2013;8:e66833 pubmed publisher
Lodrini M, Oehme I, Schroeder C, Milde T, Schier M, Kopp Schneider A, et al. MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma. Nucleic Acids Res. 2013;41:6018-33 pubmed publisher
Regel I, Merkl L, Friedrich T, Burgermeister E, Zimmermann W, Einwächter H, et al. Pan-histone deacetylase inhibitor panobinostat sensitizes gastric cancer cells to anthracyclines via induction of CITED2. Gastroenterology. 2012;143:99-109.e10 pubmed publisher
Bhandari D, Seo K, Jung J, Kim H, Yang S, Kang K. The regulatory role of c-MYC on HDAC2 and PcG expression in human multipotent stem cells. J Cell Mol Med. 2011;15:1603-14 pubmed publisher
product information
Catalog Number :
sc-81599
Product Name :
HDAC2 (3F3) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
3F3
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
HDAC2
Specificity :
mouse, rat, human, bovine
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA