product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
HDAC1 (10E2) Antibody
catalog :
sc-81598
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10E2
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 26
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 4a
Kim C, Park S, Lee S, Kim Y, Jang S, Woo S, et al. NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development. Nucleic Acids Res. 2021;49:5760-5778 pubmed publisher
  • western blot; human; loading ...; fig 3s2a
Shi K, Yin X, Cai M, Yan Y, Jia C, Ma P, et al. PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors. elife. 2019;8: pubmed publisher
  • western blot; human; 1:660; loading ...; fig 3a
ElHady A, Abdel Halim M, Abadi A, Engel M. Development of Selective Clk1 and -4 Inhibitors for Cellular Depletion of Cancer-Relevant Proteins. J Med Chem. 2017;60:5377-5391 pubmed publisher
  • western blot; rat; 1:500; loading ...; fig 4c
Honjoh C, Chihara K, Yoshiki H, Yamauchi S, Takeuchi K, Kato Y, et al. Association of C-Type Lectin Mincle with FcεRIβγ Subunits Leads to Functional Activation of RBL-2H3 Cells through Syk. Sci Rep. 2017;7:46064 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 1b
Jostes S, Nettersheim D, Fellermeyer M, Schneider S, Hafezi F, Honecker F, et al. The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo. J Cell Mol Med. 2017;21:1300-1314 pubmed publisher
  • western blot; human; fig 3
Agudelo M, Figueroa G, Parira T, Yndart A, Muñoz K, Atluri V, et al. Profile of Class I Histone Deacetylases (HDAC) by Human Dendritic Cells after Alcohol Consumption and In Vitro Alcohol Treatment and Their Implication in Oxidative Stress: Role of HDAC Inhibitors Trichostatin A and Mocetinostat. PLoS ONE. 2016;11:e0156421 pubmed publisher
  • western blot; rat; fig 8d
Smith C, D Mello S. Cell and Context-Dependent Effects of the Heat Shock Protein DNAJB6 on Neuronal Survival. Mol Neurobiol. 2016;53:5628-39 pubmed publisher
  • western blot; human; 1:1000; fig 3
  • western blot; mouse; 1:1000; fig 6
Szerlong H, Herman J, Krause C, DeLuca J, Skoultchi A, Winger Q, et al. Proteomic characterization of the nucleolar linker histone H1 interaction network. J Mol Biol. 2015;427:2056-71 pubmed publisher
  • western blot; human; fig 1b
Van Beek M, Oravecz Wilson K, Delekta P, Gu S, Li X, Jin X, et al. Bcl10 links saturated fat overnutrition with hepatocellular NF-kB activation and insulin resistance. Cell Rep. 2012;1:444-52 pubmed
Lee J, Kang H. Nucleolin Regulates Pulmonary Artery Smooth Muscle Cell Proliferation under Hypoxia by Modulating miRNA Expression. Cells. 2023;12: pubmed publisher
Kang H, Seo Y, Yun J, Song S, Han D, Cho E, et al. Metformin and Niclosamide Synergistically Suppress Wnt and YAP in APC-Mutated Colorectal Cancer. Cancers (Basel). 2021;13: pubmed publisher
Pedro K, Agosto L, Sewell J, Eberenz K, He X, Fuxman Bass J, et al. A functional screen identifies transcriptional networks that regulate HIV-1 and HIV-2. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Zhang L, Yang J, Luo Y, Liu F, Yuan Y, Zhuang S. A p53/lnc-Ip53 Negative Feedback Loop Regulates Tumor Growth and Chemoresistance. Adv Sci (Weinh). 2020;7:2001364 pubmed publisher
Haque M, Li J, Huang Y, Almowaled M, Barger C, Karpf A, et al. NPM-ALK Is a Key Regulator of the Oncoprotein FOXM1 in ALK-Positive Anaplastic Large Cell Lymphoma. Cancers (Basel). 2019;11: pubmed publisher
Lu Y, Stuart J, Talbot Cooper C, Agrawal Singh S, Huntly B, Smid A, et al. Histone deacetylase 4 promotes type I interferon signaling, restricts DNA viruses, and is degraded via vaccinia virus protein C6. Proc Natl Acad Sci U S A. 2019;116:11997-12006 pubmed publisher
Soday L, Lu Y, Albarnaz J, Davies C, Antrobus R, Smith G, et al. Quantitative Temporal Proteomic Analysis of Vaccinia Virus Infection Reveals Regulation of Histone Deacetylases by an Interferon Antagonist. Cell Rep. 2019;27:1920-1933.e7 pubmed publisher
Streubel G, Fitzpatrick D, Oliviero G, Scelfo A, Moran B, Das S, et al. Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal. EMBO J. 2017;36:2216-2232 pubmed publisher
Desai M, Han G, Ross M. Programmed hyperphagia in offspring of obese dams: Altered expression of hypothalamic nutrient sensors, neurogenic factors and epigenetic modulators. Appetite. 2016;99:193-199 pubmed publisher
Carey T, Cao Z, Choi I, Ganguly A, Wilson C, Paul S, et al. BRG1 Governs Nanog Transcription in Early Mouse Embryos and Embryonic Stem Cells via Antagonism of Histone H3 Lysine 9/14 Acetylation. Mol Cell Biol. 2015;35:4158-69 pubmed publisher
Hagelkruys A, Lagger S, Krahmer J, Leopoldi A, Artaker M, Pusch O, et al. A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. Development. 2014;141:604-616 pubmed publisher
Kaufmann A, Keim A, Thiel G. Regulation of immediate-early gene transcription following activation of G?(q)-coupled designer receptors. J Cell Biochem. 2013;114:681-96 pubmed publisher
Thiel G, Lesch A, Keim A. Transcriptional response to calcium-sensing receptor stimulation. Endocrinology. 2012;153:4716-28 pubmed
Liu Y, Peng L, Seto E, Huang S, Qiu Y. Modulation of histone deacetylase 6 (HDAC6) nuclear import and tubulin deacetylase activity through acetylation. J Biol Chem. 2012;287:29168-74 pubmed publisher
Thiel G, Rössler O. Immediate-early transcriptional response to angiotensin II in human adrenocortical cells. Endocrinology. 2011;152:4211-23 pubmed publisher
Delekta P, Apel I, Gu S, Siu K, Hattori Y, McAllister Lucas L, et al. Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3·Bcl10·MALT1 signalosome. J Biol Chem. 2010;285:41432-42 pubmed publisher
Muller I, Endo T, Thiel G. Regulation of AP-1 activity in glucose-stimulated insulinoma cells. J Cell Biochem. 2010;110:1481-94 pubmed publisher
product information
Catalog Number :
sc-81598
Product Name :
HDAC1 (10E2) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
10E2
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
HDAC1
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA