| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; fig 1
| Wang W, Acehan D, Kao C, Jane W, Uryu K, Tsou M. De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly. elife. 2015;4: pubmed publisher |
- immunocytochemistry; mouse; 1:1000; fig 4s1c
| LoMastro G, Drown C, Maryniak A, Jewett C, Strong M, HOLLAND A. PLK4 drives centriole amplification and apical surface area expansion in multiciliated cells. elife. 2022;11: pubmed publisher |
- western blot; human; 1:1000; fig s6d
| Hatzopoulos G, Kükenshöner T, Banterle N, Favez T, Flückiger I, Hamel V, et al. Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly. Nat Commun. 2021;12:3805 pubmed publisher |
- immunocytochemistry; human; fig 3d
| Steib E, Laporte M, Gambarotto D, Olieric N, Zheng C, Borgers S, et al. WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity. elife. 2020;9: pubmed publisher |
- immunocytochemistry; human; 1:200; loading ...; fig 6e
| Moyer T, HOLLAND A. PLK4 promotes centriole duplication by phosphorylating STIL to link the procentriole cartwheel to the microtubule wall. elife. 2019;8: pubmed publisher |
- western blot; human; 1:500; loading ...; fig 6e
| Shumilov A, Tsai M, Schlosser Y, Kratz A, Bernhardt K, Fink S, et al. Epstein-Barr virus particles induce centrosome amplification and chromosomal instability. Nat Commun. 2017;8:14257 pubmed publisher |
- immunocytochemistry; human; 1:500; loading ...; fig 2e
| Fournier M, Orpinell M, Grauffel C, Scheer E, Garnier J, Ye T, et al. KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification. Nat Commun. 2016;7:13227 pubmed publisher |
- immunocytochemistry; human; 1:300; fig s2
| Guen V, Gamble C, Perez D, Bourassa S, Zappel H, Gartner J, et al. STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis. Cell Cycle. 2016;15:678-88 pubmed publisher |
- immunocytochemistry; human; 1:200; fig 2
| Van de Mark D, Kong D, Loncarek J, Stearns T. MDM1 is a microtubule-binding protein that negatively regulates centriole duplication. Mol Biol Cell. 2015;26:3788-802 pubmed publisher |
- immunocytochemistry; human; 1:500; fig 3
- western blot; human; 1:500; fig 6
| Shukla A, Kong D, Sharma M, Magidson V, Loncarek J. Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation. Nat Commun. 2015;6:8077 pubmed publisher |
- immunocytochemistry; human; 1:100; fig 2
| Kim S, Lee K, Choi J, Ringstad N, Dynlacht B. Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle. Nat Commun. 2015;6:8087 pubmed publisher |
- immunocytochemistry; human
| Vertii A, Zimmerman W, Ivshina M, Doxsey S. Centrosome-intrinsic mechanisms modulate centrosome integrity during fever. Mol Biol Cell. 2015;26:3451-63 pubmed publisher |
- western blot; human; 1:1000; fig 1g
| Moyer T, Clutario K, Lambrus B, Daggubati V, Holland A. Binding of STIL to Plk4 activates kinase activity to promote centriole assembly. J Cell Biol. 2015;209:863-78 pubmed publisher |
- immunocytochemistry; human; fig s1
| Panic M, Hata S, Neuner A, Schiebel E. The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes. PLoS Genet. 2015;11:e1005243 pubmed publisher |
- western blot; human; 1:1000
| Shiratsuchi G, Takaoka K, Ashikawa T, Hamada H, Kitagawa D. RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity. EMBO J. 2015;34:97-114 pubmed publisher |
- western blot; human; 1:1000
| Ohta M, Ashikawa T, Nozaki Y, Kozuka Hata H, Goto H, Inagaki M, et al. Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole. Nat Commun. 2014;5:5267 pubmed publisher |
- immunohistochemistry; mouse; 1:500; fig 1
| Kong D, Farmer V, Shukla A, James J, Gruskin R, Kiriyama S, et al. Centriole maturation requires regulated Plk1 activity during two consecutive cell cycles. J Cell Biol. 2014;206:855-65 pubmed publisher |
- immunocytochemistry; human; 1:100
| Douthwright S, Sluder G. Link between DNA damage and centriole disengagement/reduplication in untransformed human cells. J Cell Physiol. 2014;229:1427-36 pubmed publisher |
- western blot; human; fig 2
| Xu Q, Zhang Y, Xiong X, Huang Y, Salisbury J, Hu J, et al. PIPKI? targets to the centrosome and restrains centriole duplication. J Cell Sci. 2014;127:1293-305 pubmed publisher |
| Shin M, Lee J, Lee H, Kumar V, Kim J, Park S. Deup1 Expression Interferes with Multiciliated Differentiation. Mol Cells. 2023;46:746-756 pubmed publisher |
| Takao D, Watanabe K, Kuroki K, Kitagawa D. Feedback loops in the Plk4-STIL-HsSAS6 network coordinate site selection for procentriole formation. Biol Open. 2019;8: pubmed publisher |
| Kim D, Ahn J, Han H, Kim H, Hwang J, Lee K, et al. Cep131 overexpression promotes centrosome amplification and colon cancer progression by regulating Plk4 stability. Cell Death Dis. 2019;10:570 pubmed publisher |
| Fong C, Ozaki K, Tsou M. PPP1R35 ensures centriole homeostasis by promoting centriole-to-centrosome conversion. Mol Biol Cell. 2018;29:2801-2808 pubmed publisher |
| Kovacs L, Chao Chu J, Schneider S, Gottardo M, Tzolovsky G, Dzhindzhev N, et al. Gorab is a Golgi protein required for structure and duplication of Drosophila centrioles. Nat Genet. 2018;50:1021-1031 pubmed publisher |
| Mori M, Hazan R, Danielian P, Mahoney J, Li H, LU J, et al. Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis. Nat Commun. 2017;8:15857 pubmed publisher |
| Loukil A, Tormanen K, Sütterlin C. The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome. J Cell Biol. 2017;216:1287-1300 pubmed publisher |
| Tsuchiya Y, Yoshiba S, Gupta A, Watanabe K, Kitagawa D. Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole. Nat Commun. 2016;7:12567 pubmed publisher |
| Agircan F, Hata S, Nussbaum Krammer C, Atorino E, Schiebel E. Proximity mapping of human separase by the BioID approach. Biochem Biophys Res Commun. 2016;478:656-62 pubmed publisher |
| Chen C, Tian F, Lu L, Wang Y, Xiao Z, Yu C, et al. Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction. J Cell Sci. 2015;128:3290-303 pubmed publisher |
| Keller D, Orpinell M, Olivier N, Wachsmuth M, Mahen R, Wyss R, et al. Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells. J Cell Biol. 2014;204:697-712 pubmed publisher |
| Wang W, Tay H, Soni R, Perumal G, Goll M, Macaluso F, et al. CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base. Nat Cell Biol. 2013;15:591-601 pubmed publisher |
| Hatch E, Kulukian A, Holland A, Cleveland D, Stearns T. Cep152 interacts with Plk4 and is required for centriole duplication. J Cell Biol. 2010;191:721-9 pubmed publisher |
| Yang C, Kasbek C, Majumder S, Yusof A, Fisk H. Mps1 phosphorylation sites regulate the function of centrin 2 in centriole assembly. Mol Biol Cell. 2010;21:4361-72 pubmed publisher |
