| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:500; fig 3h
| Hu X, Villodre E, Larson R, Rahal O, Wang X, Gong Y, et al. Decorin-mediated suppression of tumorigenesis, invasion, and metastasis in inflammatory breast cancer. Commun Biol. 2021;4:72 pubmed publisher |
- western blot; human; loading ...; fig 3d
| Varela Eirin M, Carpintero Fernández P, Sánchez Temprano A, Varela Vazquez A, Paíno C, Casado Diaz A, et al. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. Aging (Albany NY). 2020;12:15882-15905 pubmed publisher |
- western blot; human; 1:200; loading ...; fig s2a
| Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2a
| Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Paul D, Islam S, Manne R, Dinesh U, Malonia S, Maity B, et al. F-box protein FBXO16 functions as a tumor suppressor by attenuating nuclear β-catenin function. J Pathol. 2019;248:266-279 pubmed publisher |
- western blot; mouse; 1:100; loading ...; fig 2b
| Taparra K, Wang H, Malek R, Lafargue A, Barbhuiya M, Wang X, et al. O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis. J Clin Invest. 2018;128:4924-4937 pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- western blot; human; 1:50; fig s6i
| Wang J, Ye Q, Cao Y, Guo Y, Huang X, Mi W, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017;8:2207 pubmed publisher |
- western blot; human; loading ...; fig 2b
| Roberts C, Shahin S, Loeza J, Dellinger T, Williams J, Glackin C. Disruption of TWIST1-RELA binding by mutation and competitive inhibition to validate the TWIST1 WR domain as a therapeutic target. BMC Cancer. 2017;17:184 pubmed publisher |
- western blot; human; 1:200; loading ...; fig 2d
| Kusumoto H, Shintani Y, Kanzaki R, Kawamura T, Funaki S, Minami M, et al. Podocalyxin influences malignant potential by controlling epithelial-mesenchymal transition in lung adenocarcinoma. Cancer Sci. 2017;108:528-535 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 1a
| Roberts C, Tran M, Pitruzzello M, Wen W, Loeza J, Dellinger T, et al. TWIST1 drives cisplatin resistance and cell survival in an ovarian cancer model, via upregulation of GAS6, L1CAM, and Akt signalling. Sci Rep. 2016;6:37652 pubmed publisher |
- western blot; human; fig 5b
| Koch K, Hartmann R, Schröter F, Suwala A, Maciaczyk D, Krüger A, et al. Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells. Oncotarget. 2016;7:73414-73431 pubmed publisher |
- immunocytochemistry; human; 1:500; loading ...; fig 6c
- western blot; human; 1:500; loading ...; fig 5a
| Chen B, Zeng X, He Y, Wang X, Liang Z, Liu J, et al. STC2 promotes the epithelial-mesenchymal transition of colorectal cancer cells through AKT-ERK signaling pathways. Oncotarget. 2016;7:71400-71416 pubmed publisher |
- chromatin immunoprecipitation; human; loading ...; fig 2b
| Orlandella F, Di Maro G, Ugolini C, Basolo F, Salvatore G. TWIST1/miR-584/TUSC2 pathway induces resistance to apoptosis in thyroid cancer cells. Oncotarget. 2016;7:70575-70588 pubmed publisher |
- western blot; human; fig 6a
| Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed publisher |
- western blot; human; 1:100; loading ...; fig 5c
| Liu S, Zhou F, Shen Y, Zhang Y, Yin H, Zeng Y, et al. Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells. Oncotarget. 2016;7:32876-92 pubmed publisher |
- western blot; human; 1:100; fig 1
| Sakamoto A, Akiyama Y, Shimada S, Zhu W, Yuasa Y, Tanaka S. DNA Methylation in the Exon 1 Region and Complex Regulation of Twist1 Expression in Gastric Cancer Cells. PLoS ONE. 2015;10:e0145630 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 1c
| Goodnough L, Dinuoscio G, ATIT R. Twist1 contributes to cranial bone initiation and dermal condensation by maintaining Wnt signaling responsiveness. Dev Dyn. 2016;245:144-56 pubmed publisher |
- western blot; human; loading ...; fig 1c
- western blot; mouse; loading ...; fig 1b
| Gajula R, Chettiar S, Williams R, Nugent K, Kato Y, Wang H, et al. Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cells. Neoplasia. 2015;17:16-31 pubmed publisher |
- western blot; human; loading ...; fig 3c
| Sun Z, Zhang C, Zou X, Jiang G, Xu Z, Li W, et al. Special AT-rich sequence-binding protein-1 participates in the maintenance of breast cancer stem cells through regulation of the Notch signaling pathway and expression of Snail1 and Twist1. Mol Med Rep. 2015;11:3235-542 pubmed publisher |
| Beedle A, Jaganathan A, Albajar Sigal xe9 s A, Yavitt F, Bera K, Andreu I, et al. Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton. bioRxiv. 2023;: pubmed publisher |
| Streitfeld W, Dalton A, Howley B, Howe P. PCBP1 regulates LIFR through FAM3C to maintain breast cancer stem cell self-renewal and invasiveness. Cancer Biol Ther. 2023;24:2271638 pubmed publisher |
| Andreu I, Granero Moya I, Chahare N, Clein K, Molina Jordàn M, Beedle A, et al. Mechanical force application to the nucleus regulates nucleocytoplasmic transport. Nat Cell Biol. 2022;24:896-905 pubmed publisher |
| Xing Y, Wei X, Liu Y, Wang M, Sui Z, Wang X, et al. Autophagy inhibition mediated by MCOLN1/TRPML1 suppresses cancer metastasis via regulating a ROS-driven TP53/p53 pathway. Autophagy. 2021;:1-23 pubmed publisher |
| Grisard E, Coan M, Cesaratto L, Rigo I, Zandonà L, Paulitti A, et al. Sleeping beauty genetic screen identifies miR-23b::BTBD7 gene interaction as crucial for colorectal cancer metastasis. EBioMedicine. 2019;46:79-93 pubmed publisher |
| Hu Q, Myers M, Fang W, Yao M, Brummer G, Hawj J, et al. Role of ALDH1A1 and HTRA2 expression to CCL2/CCR2 mediated breast cancer cell growth and invasion. Biol Open. 2019;: pubmed publisher |
| Sowamber R, Chehade R, Bitar M, Dodds L, Milea A, Slomovitz B, et al. CCAAT/enhancer binding protein delta (C/EBPδ) demonstrates a dichotomous role in tumour initiation and promotion of epithelial carcinoma. EBioMedicine. 2019;: pubmed publisher |
| Varela Eirin M, Varela Vazquez A, Guitián Caamaño A, Paíno C, Mato V, Largo R, et al. Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis. Cell Death Dis. 2018;9:1166 pubmed publisher |
| Sirka O, Shamir E, Ewald A. Myoepithelial cells are a dynamic barrier to epithelial dissemination. J Cell Biol. 2018;217:3368-3381 pubmed publisher |
| Guo D, Guo J, Li X, Guan F. Enhanced motility and proliferation by miR-10b/FUT8/p-AKT axis in breast cancer cells. Oncol Lett. 2018;16:2097-2104 pubmed publisher |
| Li X, Zhang Z, Zhang Y, Cao Y, Wei H, Wu Z. Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16INK4a inactivation. J Exp Clin Cancer Res. 2018;37:39 pubmed publisher |
| Govindarajalu G, Selvam M, Palchamy E, Baluchamy S. N-terminal truncations of human bHLH transcription factor Twist1 leads to the formation of aggresomes. Mol Cell Biochem. 2018;439:75-85 pubmed publisher |
| Recouvreux M, Wu J, Gao A, Zonis S, Chesnokova V, Bhowmick N, et al. Androgen Receptor Regulation of Local Growth Hormone in Prostate Cancer Cells. Endocrinology. 2017;158:2255-2268 pubmed publisher |
| Bergeman J, Caillier A, Houle F, Gagné L, Huot M. Localized translation regulates cell adhesion and transendothelial migration. J Cell Sci. 2016;129:4105-4117 pubmed |
| Valcourt U, Carthy J, Okita Y, Alcaraz L, Kato M, Thuault S, et al. Analysis of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor β. Methods Mol Biol. 2016;1344:147-81 pubmed publisher |
| Wei S, Fattet L, Tsai J, Guo Y, Pai V, Majeski H, et al. Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway. Nat Cell Biol. 2015;17:678-88 pubmed publisher |
| Finlay J, Roberts C, Lowe G, Loeza J, Rossi J, Glackin C. RNA-based TWIST1 inhibition via dendrimer complex to reduce breast cancer cell metastasis. Biomed Res Int. 2015;2015:382745 pubmed publisher |
| Shamir E, Pappalardo E, Jorgens D, Coutinho K, Tsai W, Aziz K, et al. Twist1-induced dissemination preserves epithelial identity and requires E-cadherin. J Cell Biol. 2014;204:839-56 pubmed publisher |
| Zhou Y, Huang Z, Wu S, Zang X, Liu M, Shi J. miR-33a is up-regulated in chemoresistant osteosarcoma and promotes osteosarcoma cell resistance to cisplatin by down-regulating TWIST. J Exp Clin Cancer Res. 2014;33:12 pubmed publisher |
| Dong P, Kaneuchi M, Watari H, Sudo S, Sakuragi N. MicroRNA-106b modulates epithelial-mesenchymal transition by targeting TWIST1 in invasive endometrial cancer cell lines. Mol Carcinog. 2014;53:349-59 pubmed publisher |
| Ding S, Yang Y, Li X, Michelli Rivera A, Han S, Wang L, et al. Epithelial-mesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanism in lung epithelial cells. Toxicol Appl Pharmacol. 2013;269:61-71 pubmed publisher |
| Zhou Y, Zang X, Huang Z, Zhang C. TWIST interacts with endothelin-1/endothelin A receptor signaling in osteosarcoma cell survival against cisplatin. Oncol Lett. 2013;5:857-861 pubmed |
| Wu J, Liao Q, He H, Zhong D, Yin K. TWIST interacts with ?-catenin signaling on osteosarcoma cell survival against cisplatin. Mol Carcinog. 2014;53:440-6 pubmed publisher |
| Shiota M, Zardan A, Takeuchi A, Kumano M, Beraldi E, Naito S, et al. Clusterin mediates TGF-?-induced epithelial-mesenchymal transition and metastasis via Twist1 in prostate cancer cells. Cancer Res. 2012;72:5261-72 pubmed publisher |
| Dong P, Karaayvaz M, Jia N, Kaneuchi M, Hamada J, Watari H, et al. Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis. Oncogene. 2013;32:3286-95 pubmed publisher |
| Shiota M, Takeuchi A, Yokomizo A, Kashiwagi E, Tatsugami K, Naito S. Methyltransferase inhibitor adenosine dialdehyde suppresses androgen receptor expression and prostate cancer growth. J Urol. 2012;188:300-6 pubmed publisher |
| Shiota M, Song Y, Takeuchi A, Yokomizo A, Kashiwagi E, Kuroiwa K, et al. Antioxidant therapy alleviates oxidative stress by androgen deprivation and prevents conversion from androgen dependent to castration resistant prostate cancer. J Urol. 2012;187:707-14 pubmed publisher |
| Salerno P, Garcia Rostan G, Piccinin S, Bencivenga T, Di Maro G, Doglioni C, et al. TWIST1 plays a pleiotropic role in determining the anaplastic thyroid cancer phenotype. J Clin Endocrinol Metab. 2011;96:E772-81 pubmed publisher |
| Wirrig E, Hinton R, Yutzey K. Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves. J Mol Cell Cardiol. 2011;50:561-9 pubmed publisher |
| Shiota M, Song Y, Yokomizo A, Kiyoshima K, Tada Y, Uchino H, et al. Foxo3a suppression of urothelial cancer invasiveness through Twist1, Y-box-binding protein 1, and E-cadherin regulation. Clin Cancer Res. 2010;16:5654-63 pubmed publisher |
| Shiota M, Yokomizo A, Itsumi M, Uchiumi T, Tada Y, Song Y, et al. Twist1 and Y-box-binding protein-1 promote malignant potential in bladder cancer cells. BJU Int. 2011;108:E142-9 pubmed publisher |
| Zhang Z, Sui P, Dong A, Hassell J, Cserjesi P, Chen Y, et al. Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb. Development. 2010;137:3417-26 pubmed publisher |
| Chakraborty S, Wirrig E, Hinton R, Merrill W, Spicer D, Yutzey K. Twist1 promotes heart valve cell proliferation and extracellular matrix gene expression during development in vivo and is expressed in human diseased aortic valves. Dev Biol. 2010;347:167-79 pubmed publisher |
| Shiota M, Yokomizo A, Tada Y, Uchiumi T, Inokuchi J, Tatsugami K, et al. P300/CBP-associated factor regulates Y-box binding protein-1 expression and promotes cancer cell growth, cancer invasion and drug resistance. Cancer Sci. 2010;101:1797-806 pubmed publisher |
| Yin G, Chen R, Alvero A, Fu H, Holmberg J, Glackin C, et al. TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214. Oncogene. 2010;29:3545-53 pubmed publisher |
| Pozharskaya V, Torres Gonzalez E, Rojas M, Gal A, Amin M, Dollard S, et al. Twist: a regulator of epithelial-mesenchymal transition in lung fibrosis. PLoS ONE. 2009;4:e7559 pubmed publisher |
| Shiota M, Yokomizo A, Tada Y, Inokuchi J, Kashiwagi E, Masubuchi D, et al. Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression. Oncogene. 2010;29:237-50 pubmed publisher |
| Isenmann S, Arthur A, Zannettino A, Turner J, Shi S, Glackin C, et al. TWIST family of basic helix-loop-helix transcription factors mediate human mesenchymal stem cell growth and commitment. Stem Cells. 2009;27:2457-68 pubmed publisher |
| Shiota M, Izumi H, Tanimoto A, Takahashi M, Miyamoto N, Kashiwagi E, et al. Programmed cell death protein 4 down-regulates Y-box binding protein-1 expression via a direct interaction with Twist1 to suppress cancer cell growth. Cancer Res. 2009;69:3148-56 pubmed publisher |
| Shiota M, Izumi H, Onitsuka T, Miyamoto N, Kashiwagi E, Kidani A, et al. Twist and p53 reciprocally regulate target genes via direct interaction. Oncogene. 2008;27:5543-53 pubmed publisher |
