Published Application/Species/Sample/Dilution | Reference |
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- immunoprecipitation; human; 4 ug/ml; loading ...; fig 5b
| Xu H, Xu S, Xie S, Zhang Y, Yang J, Zhang W, et al. MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway. elife. 2019;8: pubmed publisher
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- western blot; human; 1:1000; tbl s1
| Yasui T, Uezono N, Nakashima H, Noguchi H, Matsuda T, Noda Andoh T, et al. Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. Stem Cell Reports. 2017;8:1743-1756 pubmed publisher
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- western blot; mouse; loading ...; fig 1d
| Gopinath S. Inhibition of Stat3 signaling ameliorates atrophy of the soleus muscles in mice lacking the vitamin D receptor. Skelet Muscle. 2017;7:2 pubmed publisher
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- western blot; mouse; 1:400; fig 4
| Suman S, Kumar S, Fornace A, Datta K. Space radiation exposure persistently increased leptin and IGF1 in serum and activated leptin-IGF1 signaling axis in mouse intestine. Sci Rep. 2016;6:31853 pubmed publisher
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- immunocytochemistry; human; fig 6a
- western blot; human; fig 4
| Luna Vital D, Liang K, González de MejÃa E, Loarca Piña G. Dietary peptides from the non-digestible fraction of Phaseolus vulgaris L. decrease angiotensin II-dependent proliferation in HCT116 human colorectal cancer cells through the blockade of the renin-angiotensin system. Food Funct. 2016;7:2409-19 pubmed publisher
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- western blot; mouse; fig 6
| Illich D, Zhang M, Ursu A, Osorno R, Kim K, Yoon J, et al. Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs. Cell Rep. 2016;15:787-800 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:200
- immunocytochemistry; human; 1:50; fig 4
- western blot; human; 1:1000; fig 3
| Guo H, Liu J, Ben Q, Qu Y, Li M, Wang Y, et al. The aspirin-induced long non-coding RNA OLA1P2 blocks phosphorylated STAT3 homodimer formation. Genome Biol. 2016;17:24 pubmed publisher
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- immunocytochemistry; human
| van de Vyver M, Engelbrecht L, Smith C, Myburgh K. Neutrophil and monocyte responses to downhill running: Intracellular contents of MPO, IL-6, IL-10, pstat3, and SOCS3. Scand J Med Sci Sports. 2016;26:638-47 pubmed publisher
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- immunocytochemistry; human; 1:100; fig 3
| Jin G, Zhao J, Yang Y, Liu K, Jiang Y, Zhang X, et al. JAK/STAT3 signaling pathway mediates endothelial-like differentiation of immature dendritic cells. Oncol Lett. 2015;10:3471-3477 pubmed
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- western blot; mouse; 1:100; fig 1
- western blot; human; 1:100; fig 1
| Chen H, Aksoy I, Gonnot F, Osteil P, Aubry M, Hamela C, et al. Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency. Nat Commun. 2015;6:7095 pubmed publisher
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- western blot; rat; 1:1000; fig 8
| Zou Z, Cai Y, Chen Y, Chen S, Liu L, Shen Z, et al. Bone marrow-derived mesenchymal stem cells attenuate acute liver injury and regulate the expression of fibrinogen-like-protein 1 and signal transducer and activator of transcription 3. Mol Med Rep. 2015;12:2089-97 pubmed publisher
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| Kim H, Li A, Ahn S, Song H, Zhang W. Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity. Sci Rep. 2014;4:7330 pubmed publisher
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| Mou W, Xu Y, Ye Y, Chen S, Li X, Gong K, et al. Expression of Sox2 in breast cancer cells promotes the recruitment of M2 macrophages to tumor microenvironment. Cancer Lett. 2015;358:115-23 pubmed publisher
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| Vogelsang P, Karlsen M, Brun J, Jonsson R, Appel S. Altered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren's syndrome. Arthritis Res Ther. 2014;16:R166 pubmed publisher
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- western blot; mouse; 1:500
| Tan G, Cheng L, Chen T, Yu L, Tan Y. Foxm1 mediates LIF/Stat3-dependent self-renewal in mouse embryonic stem cells and is essential for the generation of induced pluripotent stem cells. PLoS ONE. 2014;9:e92304 pubmed publisher
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| Zhu H, Guariglia S, Li W, Brancho D, Wang Z, Scherer P, et al. Role of extracellular signal-regulated kinase 5 in adipocyte signaling. J Biol Chem. 2014;289:6311-22 pubmed publisher
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| Granato M, Gilardini Montani M, Zompetta C, Santarelli R, Gonnella R, Romeo M, et al. Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization. Biomolecules. 2019;9: pubmed publisher
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| Martínez García D, Pérez Hernández M, Korrodi Gregório L, Quesada R, Ramos R, Baixeras N, et al. The Natural-Based Antitumor Compound T21 Decreases Survivin Levels through Potent STAT3 Inhibition in Lung Cancer Models. Biomolecules. 2019;9: pubmed publisher
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| Muramatsu M, Akakura S, Gao L, Peresie J, Balderman B, Gelman I. SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk. Oncotarget. 2018;9:33515-33527 pubmed publisher
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| Oh R, Haak A, Smith K, Ligresti G, Choi K, Xie T, et al. RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation. J Cell Sci. 2018;131: pubmed publisher
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| Tusi B, Wolock S, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, et al. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature. 2018;555:54-60 pubmed publisher
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| Muramatsu M, Gao L, Peresie J, Balderman B, Akakura S, Gelman I. SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts. Oncotarget. 2017;8:70281-70298 pubmed publisher
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| He F, Soriano P. Dysregulated PDGFRα signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification. Development. 2017;144:4026-4036 pubmed publisher
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| Wu P, Wu D, Zhao L, Huang L, Shen G, Huang J, et al. Prognostic role of STAT3 in solid tumors: a systematic review and meta-analysis. Oncotarget. 2016;7:19863-83 pubmed publisher
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| Zaza G, Rascio F, Pontrelli P, Granata S, Stifanelli P, Accetturo M, et al. Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients. BMC Med Genomics. 2014;7:14 pubmed publisher
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| Zhang P, Zhang P, Zhou M, Jiang H, Zhang H, Shi B, et al. Exon 4 deletion variant of epidermal growth factor receptor enhances invasiveness and cisplatin resistance in epithelial ovarian cancer. Carcinogenesis. 2013;34:2639-46 pubmed publisher
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| Wang J, Chen S, Xu S, Yu X, Ma D, Hu X, et al. In vivo induction of apoptosis by fucoxanthin, a marine carotenoid, associated with down-regulating STAT3/EGFR signaling in sarcoma 180 (S180) xenografts-bearing mice. Mar Drugs. 2012;10:2055-68 pubmed publisher
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| Schilling J, Machkovech H, Kim A, Schwendener R, Schwedwener R, Schaffer J. Macrophages modulate cardiac function in lipotoxic cardiomyopathy. Am J Physiol Heart Circ Physiol. 2012;303:H1366-73 pubmed publisher
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| Gong J, Zhang J, Li B, Zeng C, You K, Chen M, et al. MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R. Oncogene. 2013;32:3071-9 pubmed publisher
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| Iglesias P, Fraga M, Costoya J. Defining hypoxic microenvironments by non-invasive functional optical imaging. Eur J Cancer. 2013;49:264-71 pubmed publisher
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| Bordone M, Lanzani M, López Costa J, Chianelli M, Franco P, Sáenz D, et al. Bacterial lipopolysaccharide protects the retina from light-induced damage. J Neurochem. 2012;122:392-403 pubmed publisher
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| Volpato A, Schultz A, Magalhães da Costa E, Correia M, Aguila M, Mandarim de Lacerda C. Maternal high-fat diet programs for metabolic disturbances in offspring despite leptin sensitivity. Neuroendocrinology. 2012;96:272-84 pubmed publisher
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| Nicolas C, Peineau S, Amici M, Csaba Z, Fafouri A, Javalet C, et al. The Jak/STAT pathway is involved in synaptic plasticity. Neuron. 2012;73:374-90 pubmed publisher
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| Iguchi Hashimoto M, Usui T, Yoshifuji H, Shimizu M, Kobayashi S, Ito Y, et al. Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-?B and increased STAT5 signals. PLoS ONE. 2011;6:e27020 pubmed publisher
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| Canino C, Mori F, Cambria A, Diamantini A, Germoni S, Alessandrini G, et al. SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells. Oncogene. 2012;31:3148-63 pubmed publisher
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| Rummel C, Matsumura K, Luheshi G. Circulating IL-6 contributes to peripheral LPS-induced mPGES-1 expression in the rat brain. Brain Res Bull. 2011;86:319-25 pubmed publisher
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| Zhou L, Too H. Mitochondrial localized STAT3 is involved in NGF induced neurite outgrowth. PLoS ONE. 2011;6:e21680 pubmed publisher
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| Osinalde N, Moss H, Arrizabalaga O, Omaetxebarria M, Blagoev B, Zubiaga A, et al. Interleukin-2 signaling pathway analysis by quantitative phosphoproteomics. J Proteomics. 2011;75:177-91 pubmed publisher
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| Cimica V, Chen H, Iyer J, Reich N. Dynamics of the STAT3 transcription factor: nuclear import dependent on Ran and importin-?1. PLoS ONE. 2011;6:e20188 pubmed publisher
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| Kirabo A, Oh S, Kasahara H, Wagner K, Sayeski P. Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice. J Mol Cell Cardiol. 2011;50:1026-34 pubmed publisher
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| Metlakunta A, Sahu M, Yasukawa H, Dhillon S, Belsham D, Yoshimura A, et al. Neuronal suppressor of cytokine signaling-3 deficiency enhances hypothalamic leptin-dependent phosphatidylinositol 3-kinase signaling. Am J Physiol Regul Integr Comp Physiol. 2011;300:R1185-93 pubmed publisher
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| Yu R, Hu X, Xu S, Jiang Z, Yang W. Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway. Eur J Pharmacol. 2011;657:10-9 pubmed publisher
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| Glienke W, Hausmann E, Bergmann L. Downregulation of STAT3 signaling induces apoptosis but also promotes anti-apoptotic gene expression in human pancreatic cancer cell lines. Tumour Biol. 2011;32:493-500 pubmed publisher
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| Humphreys E, Williams K, Adams D, Afford S. Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent apoptosis, but are insensitive to direct activation with exogenous Fas ligand. PLoS ONE. 2010;5:e14037 pubmed publisher
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| Bertucci P, Quaglino A, Pozzi A, Kordon E, Pecci A. Glucocorticoid-induced impairment of mammary gland involution is associated with STAT5 and STAT3 signaling modulation. Endocrinology. 2010;151:5730-40 pubmed publisher
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| Yue Z, Zhuang F, Liu Y, Ho C. Interrogating cell signalling network sensitively monitors cell fate transition during early differentiation of mouse embryonic stem cells. Sci China Life Sci. 2010;53:78-86 pubmed publisher
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| Chusid L, Pereira Argenziano L, Miskolci V, Vancurova I, Davidson D. Transcriptional control of cytokine release from monocytes of the newborn: effects of endogenous and exogenous interleukin-10 versus dexamethasone. Neonatology. 2010;97:108-16 pubmed publisher
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| Quaglino A, Salierno M, Pellegrotti J, Rubinstein N, Kordon E. Mechanical strain induces involution-associated events in mammary epithelial cells. BMC Cell Biol. 2009;10:55 pubmed publisher
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| Wang L, Quan J, Johnston W, Maass D, Horton J, Thomas J, et al. Age-dependent differences of interleukin-6 activity in cardiac function after burn complicated by sepsis. Burns. 2010;36:232-8 pubmed publisher
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| Zorde Khvalevsky E, Abramovitch R, Barash H, Spivak Pohis I, Rivkin L, Rachmilewitz J, et al. Toll-like receptor 3 signaling attenuates liver regeneration. Hepatology. 2009;50:198-206 pubmed publisher
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| Haller F, Löbke C, Ruschhaupt M, Schulten H, Schwager S, Gunawan B, et al. Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletions. J Pathol. 2008;216:225-35 pubmed publisher
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| Zhu P, Hata R, Cao F, Gu F, Hanakawa Y, Hashimoto K, et al. Ramified microglial cells promote astrogliogenesis and maintenance of neural stem cells through activation of Stat3 function. FASEB J. 2008;22:3866-77 pubmed publisher
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| Kim C, Sano Y, Todorova K, Carlson B, Arpa L, Celada A, et al. The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression. Nat Immunol. 2008;9:1019-27 pubmed publisher
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| Itabashi H, Maesawa C, Oikawa H, Kotani K, Sakurai E, Kato K, et al. Angiotensin II and epidermal growth factor receptor cross-talk mediated by a disintegrin and metalloprotease accelerates tumor cell proliferation of hepatocellular carcinoma cell lines. Hepatol Res. 2008;38:601-13 pubmed publisher
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| Nechemia Arbely Y, Barkan D, Pizov G, Shriki A, Rose John S, Galun E, et al. IL-6/IL-6R axis plays a critical role in acute kidney injury. J Am Soc Nephrol. 2008;19:1106-15 pubmed publisher
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| Wunderlich F, Luedde T, Singer S, Schmidt Supprian M, Baumgartl J, Schirmacher P, et al. Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis. Proc Natl Acad Sci U S A. 2008;105:1297-302 pubmed publisher
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| Metlakunta A, Sahu M, Sahu A. Hypothalamic phosphatidylinositol 3-kinase pathway of leptin signaling is impaired during the development of diet-induced obesity in FVB/N mice. Endocrinology. 2008;149:1121-8 pubmed
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| Chung B, Matak P, McKie A, Sharp P. Leptin increases the expression of the iron regulatory hormone hepcidin in HuH7 human hepatoma cells. J Nutr. 2007;137:2366-70 pubmed
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| Quaglino A, Schere Levy C, Romorini L, Meiss R, Kordon E. Mouse mammary tumors display Stat3 activation dependent on leukemia inhibitory factor signaling. Breast Cancer Res. 2007;9:R69 pubmed
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| Zhuang L, Lee C, Scolyer R, McCarthy S, Zhang X, Thompson J, et al. Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma. Mod Pathol. 2007;20:416-26 pubmed
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| Granillo A, Boffi J, Barañao L, Kordon E, Pecci A, Guberman A. STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line. Biochem Biophys Res Commun. 2007;356:727-32 pubmed
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| Rigby R, Simmons J, Greenhalgh C, Alexander W, Lund P. Suppressor of cytokine signaling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colon. Oncogene. 2007;26:4833-41 pubmed
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| Williams K, Young S, Negus A, Young L, Adams D, Afford S. C4b binding protein binds to CD154 preventing CD40 mediated cholangiocyte apoptosis: a novel link between complement and epithelial cell survival. PLoS ONE. 2007;2:e159 pubmed
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| Eidenschenk C, Jouanguy E, Alcais A, Mention J, Pasquier B, Fleckenstein I, et al. Familial NK cell deficiency associated with impaired IL-2- and IL-15-dependent survival of lymphocytes. J Immunol. 2006;177:8835-43 pubmed
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| Cao F, Hata R, Zhu P, Ma Y, Tanaka J, Hanakawa Y, et al. Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells. J Neurochem. 2006;98:459-70 pubmed
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| Qiu L, Lai R, Lin Q, Lau E, Thomazy D, Calame D, et al. Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells. Blood. 2006;108:2407-15 pubmed
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| Soto Cid A, Hernández Kelly L, Hernandez M, Manzo J, Gonzalez Mejia M, Zepeda R, et al. Signal transducers and activators of transcription 1 and 3 in prostate: effect of sexual activity. Life Sci. 2006;79:919-24 pubmed
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| Sahu A, Metlakunta A. Hypothalamic phosphatidylinositol 3-kinase-phosphodiesterase 3B-cyclic AMP pathway of leptin signalling is impaired following chronic central leptin infusion. J Neuroendocrinol. 2005;17:720-6 pubmed
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| Yadav A, Kalita A, Dhillon S, Banerjee K. JAK/STAT3 pathway is involved in survival of neurons in response to insulin-like growth factor and negatively regulated by suppressor of cytokine signaling-3. J Biol Chem. 2005;280:31830-40 pubmed
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| Gu F, Hata R, Ma Y, Tanaka J, Mitsuda N, Kumon Y, et al. Suppression of Stat3 promotes neurogenesis in cultured neural stem cells. J Neurosci Res. 2005;81:163-71 pubmed
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