product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Jun B (C-11) Antibody
catalog :
sc-8051
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-11
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 42
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human; fig 4
Kim J, Zarjou A, Traylor A, Bolisetty S, Jaimes E, Hull T, et al. In vivo regulation of the heme oxygenase-1 gene in humanized transgenic mice. Kidney Int. 2012;82:278-91 pubmed publisher
Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed publisher
Viita T, Kyheröinen S, Prajapati B, Virtanen J, Frilander M, Varjosalo M, et al. Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing. J Cell Sci. 2019;132: pubmed publisher
Yost K, Clatterbuck Soper S, Walker R, Pineda M, Zhu Y, Ester C, et al. Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells. Sci Rep. 2019;9:4544 pubmed publisher
Huang L, Zhao J, Chen H, Wan L, Inuzuka H, Guo J, et al. SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis. Nat Commun. 2018;9:3569 pubmed publisher
Hu P, Nebreda A, Hanenberg H, Kinnebrew G, Ivan M, Yoder M, et al. P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim. Nat Commun. 2018;9:3518 pubmed publisher
Wang A, Wangensteen K, WANG Y, Zahm A, Moss N, Erez N, et al. TRAP-seq identifies cystine/glutamate antiporter as a driver of recovery from liver injury. J Clin Invest. 2018;128:2297-2309 pubmed publisher
Sarikhani M, Mishra S, Maity S, Kotyada C, Wolfgeher D, Gupta M, et al. SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation. elife. 2018;7: pubmed publisher
Chen M, Wan L, Zhang J, Zhang J, Méndez L, Clohessy J, et al. Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism. Nat Commun. 2018;9:159 pubmed publisher
Sundqvist A, Morikawa M, Ren J, Vasilaki E, Kawasaki N, Kobayashi M, et al. JUNB governs a feed-forward network of TGF? signaling that aggravates breast cancer invasion. Nucleic Acids Res. 2017;: pubmed publisher
Moleirinho S, Hoxha S, Mandati V, Curtale G, Troutman S, Ehmer U, et al. Regulation of localization and function of the transcriptional co-activator YAP by angiomotin. elife. 2017;6: pubmed publisher
Wei Y, Chiang W, Sumpter R, Mishra P, Levine B. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. Cell. 2017;168:224-238.e10 pubmed publisher
Bedal K, Grassel S, Oefner P, Reinders J, Reichert T, Bauer R. Collagen XVI induces expression of MMP9 via modulation of AP-1 transcription factors and facilitates invasion of oral squamous cell carcinoma. PLoS ONE. 2014;9:e86777 pubmed publisher
Kharman Biz A, Gao H, Ghiasvand R, Zhao C, Zendehdel K, Dahlman Wright K. Expression of activator protein-1 (AP-1) family members in breast cancer. BMC Cancer. 2013;13:441 pubmed publisher
Kong H, Yoon S, Park J. The regulatory mechanism of the LY6K gene expression in human breast cancer cells. J Biol Chem. 2012;287:38889-900 pubmed publisher
Zhang Y, Fan K, Sun Q, Chen A, Shen W, Zhao Z, et al. Functional screening for miRNAs targeting Smad4 identified miR-199a as a negative regulator of TGF-? signalling pathway. Nucleic Acids Res. 2012;40:9286-97 pubmed publisher
Han B, Rorke E, Adhikary G, Chew Y, Xu W, Eckert R. Suppression of AP1 transcription factor function in keratinocyte suppresses differentiation. PLoS ONE. 2012;7:e36941 pubmed publisher
Shah M, Bhoumik A, Goel V, Dewing A, Breitwieser W, Kluger H, et al. A role for ATF2 in regulating MITF and melanoma development. PLoS Genet. 2010;6:e1001258 pubmed publisher
Deng J, Rodriguiz R, Hutchinson A, Kim I, Wetsel W, West A. MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants. Nat Neurosci. 2010;13:1128-36 pubmed publisher
Mallakin A, Sugiyama T, Kai F, Taneja P, Kendig R, Frazier D, et al. The Arf-inducing transcription factor Dmp1 encodes a transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1. Int J Cancer. 2010;126:1403-16 pubmed publisher
Pekarsky Y, Palamarchuk A, Maximov V, Efanov A, Nazaryan N, Santanam U, et al. Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL. Proc Natl Acad Sci U S A. 2008;105:19643-8 pubmed publisher
Yivgi Ohana N, Sher N, Melamed Book N, Eimerl S, Koler M, Manna P, et al. Transcription of steroidogenic acute regulatory protein in the rodent ovary and placenta: alternative modes of cyclic adenosine 3', 5'-monophosphate dependent and independent regulation. Endocrinology. 2009;150:977-89 pubmed publisher
da Costa Reis Monte Mór B, Plo I, da Cunha A, Costa G, de Albuquerque D, Jedidi A, et al. Constitutive JunB expression, associated with the JAK2 V617F mutation, stimulates proliferation of the erythroid lineage. Leukemia. 2009;23:144-52 pubmed publisher
Mao X, Orchard G, Mitchell T, Oyama N, Russell Jones R, Vermeer M, et al. A genomic and expression study of AP-1 in primary cutaneous T-cell lymphoma: evidence for dysregulated expression of JUNB and JUND in MF and SS. J Cutan Pathol. 2008;35:899-910 pubmed publisher
Mao X, Orchard G. Abnormal AP-1 protein expression in primary cutaneous B-cell lymphomas. Br J Dermatol. 2008;159:145-51 pubmed publisher
Ballaun C, Karner S, Mrass P, Mildner M, Buchberger M, Bach J, et al. Transcription of the caspase-14 gene in human epidermal keratinocytes requires AP-1 and NFkappaB. Biochem Biophys Res Commun. 2008;371:261-6 pubmed publisher
Schuler A, Schwieger M, Engelmann A, Weber K, Horn S, Muller U, et al. The MADS transcription factor Mef2c is a pivotal modulator of myeloid cell fate. Blood. 2008;111:4532-41 pubmed publisher
Yin Q, Wang X, McBride J, Fewell C, Flemington E. B-cell receptor activation induces BIC/miR-155 expression through a conserved AP-1 element. J Biol Chem. 2008;283:2654-62 pubmed
Mao X, Orchard G, Russell Jones R, Whittaker S. Abnormal activator protein 1 transcription factor expression in CD30-positive cutaneous large-cell lymphomas. Br J Dermatol. 2007;157:914-21 pubmed
Hock T, Liby K, Wright M, McConnell S, Schorpp Kistner M, Ryan T, et al. JunB and JunD regulate human heme oxygenase-1 gene expression in renal epithelial cells. J Biol Chem. 2007;282:6875-86 pubmed
Licht A, Pein O, Florin L, Hartenstein B, Reuter H, Arnold B, et al. JunB is required for endothelial cell morphogenesis by regulating core-binding factor beta. J Cell Biol. 2006;175:981-91 pubmed
Hameetman L, Rozeman L, Lombaerts M, Oosting J, Taminiau A, Cleton Jansen A, et al. Peripheral chondrosarcoma progression is accompanied by decreased Indian Hedgehog signalling. J Pathol. 2006;209:501-11 pubmed
Mayr D, Kanitz V, Anderegg B, Luthardt B, Engel J, Löhrs U, et al. Analysis of gene amplification and prognostic markers in ovarian cancer using comparative genomic hybridization for microarrays and immunohistochemical analysis for tissue microarrays. Am J Clin Pathol. 2006;126:101-9 pubmed
Bosisio D, Marazzi I, Agresti A, Shimizu N, Bianchi M, Natoli G. A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity. EMBO J. 2006;25:798-810 pubmed
Florin L, Knebel J, Zigrino P, Vonderstrass B, Mauch C, Schorpp Kistner M, et al. Delayed wound healing and epidermal hyperproliferation in mice lacking JunB in the skin. J Invest Dermatol. 2006;126:902-11 pubmed
Adam E, Hansen K, Astudillo Fernandez O, Astudillo O, Coulon L, Bex F, et al. The house dust mite allergen Der p 1, unlike Der p 3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism. J Biol Chem. 2006;281:6910-23 pubmed
Song X, Tao Y, Zeng L, Yang J, Tang F, Lee L, et al. Epstein-Barr virus-encoded latent membrane protein 1 modulates cyclin D1 by c-Jun/Jun B heterodimers. Sci China C Life Sci. 2005;48:385-93 pubmed
Rozeman L, Hameetman L, van Wezel T, Taminiau A, Cleton Jansen A, Hogendoorn P, et al. cDNA expression profiling of chondrosarcomas: Ollier disease resembles solitary tumours and alteration in genes coding for components of energy metabolism occurs with increasing grade. J Pathol. 2005;207:61-71 pubmed
Desmet C, Gosset P, Henry E, Garze V, Faisca P, Vos N, et al. Treatment of experimental asthma by decoy-mediated local inhibition of activator protein-1. Am J Respir Crit Care Med. 2005;172:671-8 pubmed
Song X, Tao Y, Zeng L, Deng X, Lee L, Gong J, et al. Latent membrane protein 1 encoded by Epstein-Barr virus modulates directly and synchronously cyclin D1 and p16 by newly forming a c-Jun/Jun B heterodimer in nasopharyngeal carcinoma cell line. Virus Res. 2005;113:89-99 pubmed
Ogawa D, Stone J, Takata Y, Blaschke F, Chu V, Towler D, et al. Liver x receptor agonists inhibit cytokine-induced osteopontin expression in macrophages through interference with activator protein-1 signaling pathways. Circ Res. 2005;96:e59-67 pubmed
Ghosh S, Wu Y, Li R, Hu Y. Jun proteins modulate the ovary-specific promoter of aromatase gene in ovarian granulosa cells via a cAMP-responsive element. Oncogene. 2005;24:2236-46 pubmed
product information
Product Name :
Jun B (C-11) Antibody
Gene Name :
JUNB
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-8051
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Jun B
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
C-terminal (m)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA