product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
ErbB-4 (C-7) Antibody
catalog :
sc-8050
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-7
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 17
Reference
Sun X, Gemzell-Danielsson K, Li H, Ståbi B, Stavreus-Evers A. Expression of heparin-binding epidermal growth factor-like growth factor and its receptors in the human fallopian tube and endometrium after treatment with mifepristone. Fertil Steril. 2006;85:171-8 pubmed
Woo R, Lee J, Yu H, Song D, Baik T. Expression of ErbB4 in the apoptotic neurons of Alzheimer's disease brain. Anat Cell Biol. 2010;43:332-9 pubmed
Mukhopadhyay P, Lakshmanan I, Ponnusamy M, Chakraborty S, Jain M, Pai P, et al. MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells. PLoS ONE. 2013;8:e54455 pubmed publisher
Jackson-Fisher A, Bellinger G, Shum E, Duong J, Perkins A, Gassmann M, et al. Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4. Oncogene. 2006;25:5664-72 pubmed
Mimura S, Yamaguchi T, Ishii S, Noro E, Katsura T, Obuse C, et al. Cul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing. J Biol Chem. 2010;285:9858-67 pubmed publisher
Woo R, Lee J, Yu H, Song D, Baik T. Expression of ErbB4 in the neurons of Alzheimer's disease brain and APP/PS1 mice, a model of Alzheimer's disease. Anat Cell Biol. 2011;44:116-27 pubmed
Intoh A, Kurisaki A, Yamanaka Y, Hirano H, Fukuda H, Sugino H, et al. Proteomic analysis of membrane proteins expressed specifically in pluripotent murine embryonic stem cells. Proteomics. 2009;9:126-37 pubmed publisher
Hahn C, Wang H, Cho D, Talbot K, Gur R, Berrettini W, et al. Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nat Med. 2006;12:824-8 pubmed
Di Cara G, Marengo G, Albanese N, Marabeti M, Musso R, Cancemi P, et al. Proteomic profiling of Trastuzumab (Herceptin(R))-sensitive and -resistant SKBR-3 breast cancer cells. Anticancer Res. 2013;33:489-503 pubmed
Woo R, Lee J, Kim H, Baek C, Song D, Suh Y, et al. Neuregulin-1 protects against neurotoxicities induced by Swedish amyloid precursor protein via the ErbB4 receptor. Neuroscience. 2012;202:413-23 pubmed publisher
Rösler T, Depboylu C, Arias-Carrión O, Wozny W, Carlsson T, Höllerhage M, et al. Biodistribution and brain permeability of the extracellular domain of neuregulin-1-β1. Neuropharmacology. 2011;61:1413-8 pubmed publisher
Asadurian Y, Kurilin H, Lichtig H, Jackman A, Gonen P, Tommasino M, et al. Activities of human papillomavirus 16 E6 natural variants in human keratinocytes. J Med Virol. 2007;79:1751-60 pubmed
Wilson K, Mill C, Gallo R, Cameron E, VanBrocklin H, Settleman J, et al. The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist. Biochem J. 2012;443:133-44 pubmed publisher
Gilmore-Hebert M, Ramabhadran R, Stern D. Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways. Mol Cancer Res. 2010;8:1388-98 pubmed publisher
Mill C, Gettinger K, Riese D. Ligand stimulation of ErbB4 and a constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines. Exp Cell Res. 2011;317:392-404 pubmed publisher
Ryu J, Yu H, Cho H, Kim H, Baik T, Lee S, et al. Neuregulin-1 exerts protective effects against neurotoxicities induced by C-terminal fragments of APP via ErbB4 receptor. J Pharmacol Sci. 2012;119:73-81 pubmed
Sanui A, Yotsumoto F, Tsujioka H, Fukami T, Horiuchi S, Shirota K, et al. HB-EGF inhibition in combination with various anticancer agents enhances its antitumor effects in gastric cancer. Anticancer Res. 2010;30:3143-9 pubmed
product information
Product Name :
ErbB-4 (C-7) Antibody
Gene Name :
ERBB4
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-8050
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
ErbB-4
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM, ELISA
Epitope :
C-terminal (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
headquarters: USA