product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Bad (C-7) Antibody
catalog :
sc-8044
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-7
reactivity :
kangaroo rats, human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, other
citations: 36
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 2
O Neill K, Huang K, Zhang J, Chen Y, Luo X. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane. Genes Dev. 2016;30:973-88 pubmed publisher
  • western blot; human; fig 4
De Toni E, Ziesch A, Rizzani A, Török H, Hocke S, Lü S, et al. Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis. Oncotarget. 2016;7:9477-90 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; rat; fig 5f
Jia Z, Wang J, Shi Q, Liu S, Wang W, Tian Y, et al. SOX6 and PDCD4 enhance cardiomyocyte apoptosis through LPS-induced miR-499 inhibition. Apoptosis. 2016;21:174-83 pubmed publisher
  • western blot; human; 1:1000
Webber P, Park C, Qui M, Ramalingam S, Khuri F, Fu H, et al. Combination of heat shock protein 90 and focal adhesion kinase inhibitors synergistically inhibits the growth of non-small cell lung cancer cells. Oncoscience. 2015;2:765-776 pubmed
  • western blot; mouse; fig 7
Lee S, Kim J, Hong S, Lee A, Park E, Seo H, et al. High Inorganic Phosphate Intake Promotes Tumorigenesis at Early Stages in a Mouse Model of Lung Cancer. PLoS ONE. 2015;10:e0135582 pubmed publisher
  • western blot; human; fig 6
Akahane K, Sanda T, Mansour M, Radimerski T, DeAngelo D, Weinstock D, et al. HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia. Leukemia. 2016;30:219-28 pubmed publisher
  • western blot; human; fig 4
Berard A, Coombs K, Severini A. Quantification of the host response proteome after herpes simplex virus type 1 infection. J Proteome Res. 2015;14:2121-42 pubmed publisher
  • western blot; kangaroo rats; 1:200; fig 3
Pilchova I, Klacanova K, Chomova M, Tatarkova Z, Dobrota D, Racay P. Possible contribution of proteins of Bcl-2 family in neuronal death following transient global brain ischemia. Cell Mol Neurobiol. 2015;35:23-31 pubmed publisher
  • western blot; human; 1:100
Chondrogiannis G, Kastamoulas M, Kanavaros P, Vartholomatos G, Bai M, Baltogiannis D, et al. Cytokine effects on cell viability and death of prostate carcinoma cells. Biomed Res Int. 2014;2014:536049 pubmed publisher
Huang K, O Neill K, Li J, Zhou W, Han N, Pang X, et al. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis. Cell Res. 2019;29:942-952 pubmed publisher
Mejías Peña Y, Estébanez B, Rodriguez Miguelez P, Fernandez Gonzalo R, Almar M, De Paz J, et al. Impact of resistance training on the autophagy-inflammation-apoptosis crosstalk in elderly subjects. Aging (Albany NY). 2017;9:408-418 pubmed publisher
Fang Q, Guo S, Zhou H, Han R, Wu P, Han C. Astaxanthin protects against early burn-wound progression in rats by attenuating oxidative stress-induced inflammation and mitochondria-related apoptosis. Sci Rep. 2017;7:41440 pubmed publisher
Klanova M, Andera L, Brazina J, Svadlenka J, Benesova S, Soukup J, et al. Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma. Clin Cancer Res. 2016;22:1138-49 pubmed publisher
Li W, Song Y, Xiong C, Lu P, Xue L, Yao C, et al. Insulin induces proliferation and cardiac differentiation of P19CL6 cells in a dose-dependent manner. Dev Growth Differ. 2013;55:676-86 pubmed publisher
Ding T, Zhou Y, Sun K, Jiang W, Li W, Liu X, et al. Knockdown a water channel protein, aquaporin-4, induced glioblastoma cell apoptosis. PLoS ONE. 2013;8:e66751 pubmed publisher
Dinh P, Das A, Franco R, Pattnaik A. Heterogeneous nuclear ribonucleoprotein K supports vesicular stomatitis virus replication by regulating cell survival and cellular gene expression. J Virol. 2013;87:10059-69 pubmed publisher
Berard A, Cortens J, Krokhin O, Wilkins J, Severini A, Coombs K. Quantification of the host response proteome after mammalian reovirus T1L infection. PLoS ONE. 2012;7:e51939 pubmed publisher
Alonso Castro A, Ortiz Sánchez E, García Regalado A, Ruiz G, Núñez Martínez J, González Sánchez I, et al. Kaempferitrin induces apoptosis via intrinsic pathway in HeLa cells and exerts antitumor effects. J Ethnopharmacol. 2013;145:476-89 pubmed publisher
Bai M, Doukas M, Papoudou Bai A, Barbouti A, Stefanaki K, Galani V, et al. Immunohistological analysis of cell cycle and apoptosis regulators in thymus. Ann Anat. 2013;195:159-65 pubmed publisher
Tsapakidis K, Vlachostergios P, Voutsadakis I, Befani C, Patrikidou A, Hatzidaki E, et al. Bortezomib reverses the proliferative and antiapoptotic effect of neuropeptides on prostate cancer cells. Int J Urol. 2012;19:565-74 pubmed publisher
Dinicola S, Cucina A, Pasqualato A, D Anselmi F, Proietti S, Lisi E, et al. Antiproliferative and apoptotic effects triggered by Grape Seed Extract (GSE) versus epigallocatechin and procyanidins on colon cancer cell lines. Int J Mol Sci. 2012;13:651-64 pubmed publisher
Bonofiglio D, Cione E, Vizza D, Perri M, Pingitore A, Qi H, et al. Bid as a potential target of apoptotic effects exerted by low doses of PPAR? and RXR ligands in breast cancer cells. Cell Cycle. 2011;10:2344-54 pubmed
Leonelli M, Martins D, Britto L. TRPV1 receptors modulate retinal development. Int J Dev Neurosci. 2011;29:405-13 pubmed publisher
Polzien L, Baljuls A, Albrecht M, Hekman M, Rapp U. BAD contributes to RAF-mediated proliferation and cooperates with B-RAF-V600E in cancer signaling. J Biol Chem. 2011;286:17934-44 pubmed publisher
Jeong J, Jin C, Park C, Hong S, Kim G, Jeong Y, et al. Induction of apoptosis by cordycepin via reactive oxygen species generation in human leukemia cells. Toxicol In Vitro. 2011;25:817-24 pubmed publisher
Leksa V, Loewe R, Binder B, Schiller H, Eckerstorfer P, Forster F, et al. Soluble M6P/IGF2R released by TACE controls angiogenesis via blocking plasminogen activation. Circ Res. 2011;108:676-85 pubmed publisher
Tong J, Furukawa Y, Sherwin A, Hornykiewicz O, Kish S. Heterogeneous intrastriatal pattern of proteins regulating axon growth in normal adult human brain. Neurobiol Dis. 2011;41:458-68 pubmed publisher
He Y, Jiang Y, Li Y, Liu X, Zhang L, Liu L, et al. 19-peptide, a fragment of tumstatin, inhibits the growth of poorly differentiated gastric carcinoma cells in vitro and in vivo. J Gastroenterol Hepatol. 2010;25:935-41 pubmed publisher
Dietrich C, Greenberg V, DeSimone C, Modesitt S, van Nagell J, Craven R, et al. Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines. Gynecol Oncol. 2010;116:126-30 pubmed publisher
Polzien L, Baljuls A, Rennefahrt U, Fischer A, Schmitz W, Zahedi R, et al. Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation. J Biol Chem. 2009;284:28004-20 pubmed publisher
Hung T, Chen S, Liou J, Hsu J, Li M, Yeh Y, et al. Bax, Bak and mitochondrial oxidants are involved in hypoxia-reoxygenation-induced apoptosis in human placenta. Placenta. 2008;29:565-83 pubmed publisher
Liou J, Matijevic Aleksic N, Lee S, Wu K. Prostacyclin inhibits endothelial cell XIAP ubiquitination and degradation. J Cell Physiol. 2007;212:840-8 pubmed
Bai M, Papoudou Bai A, Horianopoulos N, Grepi C, Agnantis N, Kanavaros P. Expression of bcl2 family proteins and active caspase 3 in classical Hodgkin's lymphomas. Hum Pathol. 2007;38:103-13 pubmed
Bacon A, Fox S, Turley H, Harris A. Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer. Oncogene. 2007;26:132-41 pubmed
Yao X, Liu J, Lee E, Ling G, McCabe J. Progesterone differentially regulates pro- and anti-apoptotic gene expression in cerebral cortex following traumatic brain injury in rats. J Neurotrauma. 2005;22:656-68 pubmed
product information
Product Name :
Bad (C-7) Antibody
Gene Name :
BAD
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-8044
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Bad
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA