product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
IRS-1 (E-12) Antibody
catalog :
sc-8038
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
E-12
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 3e
Li D, Sun S, Fu J, Ouyang S, Zhao Q, Su L, et al. NAD+-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin. Theranostics. 2021;11:4381-4402 pubmed publisher
  • western blot; mouse; fig 4
Roychowdhury S, McCullough R, Sanz Garcia C, Saikia P, Alkhouri N, Matloob A, et al. Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury. Hepatology. 2016;64:1518-1533 pubmed publisher
  • western blot; rat; 1:200
Passos E, Pereira C, Gonçalves I, Rocha Rodrigues S, Silva N, Guimarães J, et al. Role of physical exercise on hepatic insulin, glucocorticoid and inflammatory signaling pathways in an animal model of non-alcoholic steatohepatitis. Life Sci. 2015;123:51-60 pubmed publisher
Mukohda M, Fang S, Wu J, Agbor L, Nair A, Ibeawuchi S, et al. RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity. J Clin Invest. 2019;129:2318-2332 pubmed publisher
Lassak A, Dean M, Wyczechowska D, Wilk A, Marrero L, Trillo Tinoco J, et al. Molecular and Structural Traits of Insulin Receptor Substrate 1/LC3 Nuclear Structures and Their Role in Autophagy Control and Tumor Cell Survival. Mol Cell Biol. 2018;38: pubmed publisher
Noguchi A, Kikuchi K, Ohtsu T, Yoshiwara M, Nakamura Y, Miyagi Y, et al. Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model. Oncol Rep. 2013;30:2603-8 pubmed publisher
Suzuki K, Momota H, Tonooka A, Noguchi H, Yamamoto K, Wanibuchi M, et al. Glioblastoma simultaneously present with adjacent meningioma: case report and review of the literature. J Neurooncol. 2010;99:147-53 pubmed publisher
Lee J, Xu Y, Lu L, Bergman B, Leitner J, Greyson C, et al. Multiple abnormalities of myocardial insulin signaling in a porcine model of diet-induced obesity. Am J Physiol Heart Circ Physiol. 2010;298:H310-9 pubmed publisher
product information
Product Name :
IRS-1 (E-12) Antibody
Gene Name :
IRS1
Size :
200 µg/ml
Catalog Number :
sc-8038
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
IRS-1
reactive species  :
m, r, h
Application :
WB, IP, IF, FCM, ELISA
Epitope :
905-1070 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA