Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; loading ...; fig 4f
| Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, et al. VPS34 stimulation of p62 phosphorylation for cancer progression. Oncogene. 2017;36:6850-6862 pubmed publisher
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- western blot; mouse; loading ...; fig s4
| Jha K, Tripurani S, Johnson G. TSSK6 is required for γH2AX formation and the histone-to-protamine transition during spermiogenesis. J Cell Sci. 2017;130:1835-1844 pubmed publisher
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- western blot; human; loading ...; fig 6f
| Dattilo V, D Antona L, Talarico C, Capula M, Catalogna G, Iuliano R, et al. SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation. Sci Rep. 2017;7:45361 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 4a
- immunocytochemistry; human; 1:50; fig 3
| Jiang P, Gan M, Yen S, McLean P, Dickson D. Histones facilitate α-synuclein aggregation during neuronal apoptosis. Acta Neuropathol. 2017;133:547-558 pubmed publisher
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- western blot; human; 1:1000; fig 3
| Liu C, Lin S, Hsu H, Yang S, Lin C, Yang M, et al. Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nat Commun. 2016;7:11798 pubmed publisher
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- western blot; mouse; loading ...; fig 9d
| Shen Z, Liu Y, Dewidar B, Hu J, Park O, Feng T, et al. Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression. Am J Pathol. 2016;186:1874-1889 pubmed publisher
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- western blot; mouse; 1:500; fig 3
| Nishikido T, Oyama J, Shiraki A, Komoda H, Node K. Deletion of Apoptosis Inhibitor of Macrophage (AIM)/CD5L Attenuates the Inflammatory Response and Infarct Size in Acute Myocardial Infarction. J Am Heart Assoc. 2016;5:e002863 pubmed publisher
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- western blot; mouse; fig 2
- western blot; human; fig s1
| Thornton T, Delgado P, Chen L, Salas B, Krementsov D, Fernández M, et al. Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response. Nat Commun. 2016;7:10553 pubmed publisher
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- other; human; loading ...; fig st1
| Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
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- western blot; human; 1:250; fig 3
| Riesenberg S, Groetchen A, Siddaway R, Bald T, Reinhardt J, Smorra D, et al. MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment. Nat Commun. 2015;6:8755 pubmed publisher
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- western blot; human; 1:500; fig 1
| Kontro H, Cannino G, Rustin P, Dufour E, Kainulainen H. DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells. PLoS ONE. 2015;10:e0131990 pubmed publisher
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- western blot; human; 1:250
| Mues M, Cheshenko N, Wilson D, Gunther Cummins L, Herold B. Dynasore disrupts trafficking of herpes simplex virus proteins. J Virol. 2015;89:6673-84 pubmed publisher
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- immunocytochemistry; mouse; fig s1
| Lindenboim L, Sasson T, Worman H, Borner C, Stein R. Cellular stress induces Bax-regulated nuclear bubble budding and rupture followed by nuclear protein release. Nucleus. 2014;5:527-41 pubmed publisher
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- western blot; human; 1:1000
| Kim T, Kim H, Kang Y, Yoon S, Lee J, Choi W, et al. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochim Biophys Acta. 2015;1850:401-10 pubmed publisher
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- western blot; human; 1:250
| Cheshenko N, Trepanier J, González P, Eugenin E, Jacobs W, Herold B. Herpes simplex virus type 2 glycoprotein H interacts with integrin ?v?3 to facilitate viral entry and calcium signaling in human genital tract epithelial cells. J Virol. 2014;88:10026-38 pubmed publisher
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- western blot; human; 1:500; loading ...; fig 8c
| Clauzure M, Valdivieso A, Massip Copiz M, Schulman G, Teiber M, Santa Coloma T. Disruption of interleukin-1? autocrine signaling rescues complex I activity and improves ROS levels in immortalized epithelial cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function. PLoS ONE. 2014;9:e99257 pubmed publisher
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- immunohistochemistry; human
| Lodhi N, Kossenkov A, Tulin A. Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark. Nucleic Acids Res. 2014;42:7028-38 pubmed publisher
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| Mundia M, Desai V, Magwood A, Baker M. Nascent DNA synthesis during homologous recombination is synergistically promoted by the rad51 recombinase and DNA homology. Genetics. 2014;197:107-19 pubmed publisher
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- western blot; mouse; fig 6
| Vellaichamy E, Das S, Subramanian U, Maeda N, Pandey K. Genetically altered mutant mouse models of guanylyl cyclase/natriuretic peptide receptor-A exhibit the cardiac expression of proinflammatory mediators in a gene-dose-dependent manner. Endocrinology. 2014;155:1045-56 pubmed publisher
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- immunoprecipitation; human
- western blot; human
| Ahmed S, Prigent S. A nuclear export signal and oxidative stress regulate ShcD subcellular localisation: a potential role for ShcD in the nucleus. Cell Signal. 2014;26:32-40 pubmed publisher
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- western blot; human; 1:500
| Wang R, Dashwood W, Nian H, LOHR C, Fischer K, Tsuchiya N, et al. NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Int J Cancer. 2011;128:2581-90 pubmed publisher
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- immunocytochemistry; human
| Kotova E, Jarnik M, Tulin A. Poly (ADP-ribose) polymerase 1 is required for protein localization to Cajal body. PLoS Genet. 2009;5:e1000387 pubmed publisher
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| Patterson V, Damrau C, Paudyal A, Reeve B, Grimes D, Stewart M, et al. Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway. Hum Mol Genet. 2009;18:1719-39 pubmed publisher
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| Viiri K, Jänis J, Siggers T, Heinonen T, Valjakka J, Bulyk M, et al. DNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositides. Mol Cell Biol. 2009;29:342-56 pubmed publisher
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| Wu R, Young I, Chen Y, Chuang S, Toubaji A, Wu M. Identification of the PTEN-ARID4B-PI3K pathway reveals the dependency on ARID4B by PTEN-deficient prostate cancer. Nat Commun. 2019;10:4332 pubmed publisher
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| Hey F, Andreadi C, Noble C, Patel B, Jin H, Kamata T, et al. Over-expressed, N-terminally truncated BRAF is detected in the nucleus of cells with nuclear phosphorylated MEK and ERK. Heliyon. 2018;4:e01065 pubmed publisher
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| Choi J, Yeo I, Kim K, Choi W, Jung J, Han S, et al. K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression. J Neuroinflammation. 2018;15:224 pubmed publisher
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| Manzo S, Hartono S, Sanz L, Marinello J, De Biasi S, Cossarizza A, et al. DNA Topoisomerase I differentially modulates R-loops across the human genome. Genome Biol. 2018;19:100 pubmed publisher
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| Ishimoto Y, Inagi R, Yoshihara D, Kugita M, Nagao S, Shimizu A, et al. Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease. Mol Cell Biol. 2017;37: pubmed publisher
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| Liu Z, Guo J, Wang Y, Weng Z, Huang B, Yu M, et al. CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development. Cell Death Differ. 2017;24:98-110 pubmed publisher
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| Dong T, Li C, Wang X, Dian L, Zhang X, Li L, et al. Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. Nat Commun. 2015;6:6522 pubmed publisher
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| Czeisler C, Mikawa T. Microtubules coordinate VEGFR2 signaling and sorting. PLoS ONE. 2013;8:e75833 pubmed publisher
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| Zhang S, Pruitt M, Tran D, Du Bois W, Zhang K, Patel R, et al. B cell-specific deficiencies in mTOR limit humoral immune responses. J Immunol. 2013;191:1692-703 pubmed publisher
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| Cheshenko N, Trepanier J, Stefanidou M, Buckley N, Gonzalez P, Jacobs W, et al. HSV activates Akt to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression. FASEB J. 2013;27:2584-99 pubmed publisher
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| Kouzine F, Gupta A, Baranello L, Wójtowicz D, Ben Aissa K, Liu J, et al. Transcription-dependent dynamic supercoiling is a short-range genomic force. Nat Struct Mol Biol. 2013;20:396-403 pubmed publisher
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| Venkatesan N, Krishnakumar S, Deepa P, Deepa M, Khetan V, Reddy M. Molecular deregulation induced by silencing of the high mobility group protein A2 gene in retinoblastoma cells. Mol Vis. 2012;18:2420-37 pubmed
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| Anderson E, Taylor M, Xue X, Martin A, Moons D, Omary M, et al. The hypoxia-inducible factor-C/EBPα axis controls ethanol-mediated hepcidin repression. Mol Cell Biol. 2012;32:4068-77 pubmed publisher
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| Acuña Sanhueza G, Faller L, George B, Koffler J, Misetic V, Flechtenmacher C, et al. Opposing function of MYBBP1A in proliferation and migration of head and neck squamous cell carcinoma cells. BMC Cancer. 2012;12:72 pubmed publisher
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| Hanada N, Takahata T, Zhou Q, Ye X, Sun R, Itoh J, et al. Methylation of the KEAP1 gene promoter region in human colorectal cancer. BMC Cancer. 2012;12:66 pubmed publisher
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| Zhao F, Siu M, Jiang L, Tam K, Ngan H, Le X, et al. Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival. Histopathology. 2011;59:1163-72 pubmed publisher
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| Hou Y, Chiu W, Yeh C, Yeh S. Glutamine modulates lipopolysaccharide-induced activation of NF-?B via the Akt/mTOR pathway in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2012;302:L174-83 pubmed publisher
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| Ceballos M, Parody J, Alvarez M, Ingaramo P, Carnovale C, Carrillo M. Interferon-?2b and transforming growth factor-?1 treatments on HCC cell lines: Are Wnt/?-catenin pathway and Smads signaling connected in hepatocellular carcinoma?. Biochem Pharmacol. 2011;82:1682-91 pubmed publisher
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| Cui H, Shao C, Liu Q, Yu W, Fang J, Yu W, et al. Heparanase enhances nerve-growth-factor-induced PC12 cell neuritogenesis via the p38 MAPK pathway. Biochem J. 2011;440:273-82 pubmed publisher
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| Borkham Kamphorst E, Drews F, Weiskirchen R. Induction of lipocalin-2 expression in acute and chronic experimental liver injury moderated by pro-inflammatory cytokines interleukin-1? through nuclear factor-?B activation. Liver Int. 2011;31:656-65 pubmed publisher
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| Yang J, Ikezoe T, Nishioka C, Furihata M, Yokoyama A. AZ960, a novel Jak2 inhibitor, induces growth arrest and apoptosis in adult T-cell leukemia cells. Mol Cancer Ther. 2010;9:3386-95 pubmed publisher
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| Lv L, Lv L, Zhang Y, Kong Q. Luteolin prevents LPS-induced TNF-? expression in cardiac myocytes through inhibiting NF-?B signaling pathway. Inflammation. 2011;34:620-9 pubmed publisher
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| Cheshenko N, Trepanier J, Segarra T, Fuller A, Herold B. HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target. PLoS ONE. 2010;5:e11829 pubmed publisher
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| Li C, Cheng Y, Liao P, Kang J. Translocation of p53 to mitochondria is regulated by its lipid binding property to anionic phospholipids and it participates in cell death control. Neoplasia. 2010;12:150-60 pubmed
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| Oh S, Chen C, Abraham C. Cell-type dependent modulation of Notch signaling by the amyloid precursor protein. J Neurochem. 2010;113:262-74 pubmed publisher
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| Kim K, Jung D, Jang D, Kim Y, Kim J, Kim H, et al. Puerarin suppresses AGEs-induced inflammation in mouse mesangial cells: a possible pathway through the induction of heme oxygenase-1 expression. Toxicol Appl Pharmacol. 2010;244:106-13 pubmed publisher
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| Senf S, Dodd S, Judge A. FOXO signaling is required for disuse muscle atrophy and is directly regulated by Hsp70. Am J Physiol Cell Physiol. 2010;298:C38-45 pubmed publisher
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| Chen F, Ellis E, Strom S, Shneider B. ATPase Class I Type 8B Member 1 and protein kinase C zeta induce the expression of the canalicular bile salt export pump in human hepatocytes. Pediatr Res. 2010;67:183-7 pubmed publisher
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| Sugatani J, Osabe M, Kurosawa M, Kitamura N, Ikari A, Miwa M. Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 2 activity: cell cycle-dependent expression. Drug Metab Dispos. 2010;38:177-86 pubmed publisher
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| Yellaturu C, Deng X, Park E, Raghow R, Elam M. Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein (SREBP)-1c by posttranscriptional down-regulation of Insig-2A and its dissociation from SREBP cleavage-activating protein (SCAP).SREBP-1c complex. J Biol Chem. 2009;284:31726-34 pubmed publisher
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| Shibata N, Kakita A, Takahashi H, Ihara Y, Nobukuni K, Fujimura H, et al. Persistent cleavage and nuclear translocation of apoptosis-inducing factor in motor neurons in the spinal cord of sporadic amyotrophic lateral sclerosis patients. Acta Neuropathol. 2009;118:755-62 pubmed publisher
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| Kassi E, Sourlingas T, Spiliotaki M, Papoutsi Z, Pratsinis H, Aligiannis N, et al. Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells. Cancer Invest. 2009;27:723-33 pubmed publisher
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| Spiga F, Lightman S. Dose-dependent effects of corticosterone on nuclear glucocorticoid receptors and their binding to DNA in the brain and pituitary of the rat. Brain Res. 2009;1293:101-7 pubmed publisher
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| Kim J, Kim D, Choi J, Park J, Jeong K, Leeuwenburgh C, et al. Changes in lipid distribution during aging and its modulation by calorie restriction. Age (Dordr). 2009;31:127-42 pubmed publisher
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| Ikegami T, Narayanan K, Won S, Kamitani W, Peters C, Makino S. Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylation. PLoS Pathog. 2009;5:e1000287 pubmed publisher
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| Yellaturu C, Deng X, Cagen L, Wilcox H, Mansbach C, Siddiqi S, et al. Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles. J Biol Chem. 2009;284:7518-32 pubmed publisher
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| Sharma A, Sharma R, Chaudhary P, Vatsyayan R, Pearce V, Jeyabal P, et al. 4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells. Arch Biochem Biophys. 2008;480:85-94 pubmed publisher
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| Gressner O, Lahme B, Rehbein K, Siluschek M, Weiskirchen R, Gressner A. Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways. J Hepatol. 2008;49:758-67 pubmed publisher
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| Malmlöf M, Pääjärvi G, Hogberg J, Stenius U. Mdm2 as a sensitive and mechanistically informative marker for genotoxicity induced by benzo[a]pyrene and dibenzo[a,l]pyrene. Toxicol Sci. 2008;102:232-40 pubmed
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| Osabe M, Sugatani J, Fukuyama T, Ikushiro S, Ikari A, Miwa M. Expression of hepatic UDP-glucuronosyltransferase 1A1 and 1A6 correlated with increased expression of the nuclear constitutive androstane receptor and peroxisome proliferator-activated receptor alpha in male rats fed a high-fat and high-sucrose diet. Drug Metab Dispos. 2008;36:294-302 pubmed
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| Pinnola A, Naumova N, Shah M, Tulin A. Nucleosomal core histones mediate dynamic regulation of poly(ADP-ribose) polymerase 1 protein binding to chromatin and induction of its enzymatic activity. J Biol Chem. 2007;282:32511-9 pubmed
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| Holaska J, Wilson K. An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture. Biochemistry. 2007;46:8897-908 pubmed
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| Cheshenko N, Liu W, Satlin L, Herold B. Multiple receptor interactions trigger release of membrane and intracellular calcium stores critical for herpes simplex virus entry. Mol Biol Cell. 2007;18:3119-30 pubmed
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| Qu J, Liu G, Huang B, Chen C. Nitric oxide controls nuclear export of APE1/Ref-1 through S-nitrosation of cysteines 93 and 310. Nucleic Acids Res. 2007;35:2522-32 pubmed
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| Kajiyama Y, Tian J, Locker J. Characterization of distant enhancers and promoters in the albumin-alpha-fetoprotein locus during active and silenced expression. J Biol Chem. 2006;281:30122-31 pubmed
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| Wang Y, Fan P, Kahaleh B. Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. Arthritis Rheum. 2006;54:2271-9 pubmed
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| Shen F, Hu Z, Goswami J, Gaffen S. Identification of common transcriptional regulatory elements in interleukin-17 target genes. J Biol Chem. 2006;281:24138-48 pubmed
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| Servert P, Garcia Castro J, Díaz V, Lucas D, Gonzalez M, Martinez A C, et al. Inducible model for beta-six-mediated site-specific recombination in mammalian cells. Nucleic Acids Res. 2006;34:e1 pubmed
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